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Telomere
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about the Nobel-Prize Winning Science of Telomere Biology
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[Advances of Research on Ataxia Telangiectasia Mutated Gene and Risk Factors of Cardiovascular Disease].
[Age-related Changes of Left Ventricular Diastolic Function, NT-proBNP Level and Their Association With Leukocyte Telomere Length].
[Ageing: a matter of heart?].
[Aging and cancer: coincidence or etiologic relationship?].
[Aplastic anemia].
[Association study of telomere length with idiopathic male infertility].
[Cell senescence and pathophysiology of chronic lung diseases: role in chronic obstructive pulmonary disease].
[Cellular senescence and pulmonary disease: COPD as an example].
[Chromothripsis, an unexpected novel form of complexity for chromosomal rearrangements].
[Comparative chromosomal analysis of populations of phytophilous chironomidae Glyptotendipes glaucus (Mg.) from Chernobyl-affected territory].
[DEVELOPMENT PROGRESS OF MESENCHYMAL STEM CELLS SENESCENCE].
[Diagnosis of MECP2 duplication syndrome with molecular genetic techniques].
[Direct human DNA damage by unfavorable environmental and climatic factors].
[DNA methylation and telomere damage in occupational people exposed to coal tar pitch].
[DNA methylation level and telomere length as a basis for the biological aging clock model construction].
[Effects of DNA quality on the measurement of telomere length].
[Factors modulating ageing and longevity: Linear or more complex relationships?].
[First case of complete genomic sequencing in prostate cancer].
[Genetic characteristics of human acute lymphoblastic leukemia cell line Molt-4].
[Genotype analysis and telomere length measure in patients with dyskeratosis congenita].
[HDAC5 inhibition: a tool to stop cancer cell immortality].
[High level of expression and nuclear localization of RNA, transcribed from genome region, containing repetitive elements].
[Identification of the 1RS-7DS.7DL wheat-rye small segment translocation lines].
[JSNP Excellent Presentation Award for CINP2014].
[Length and structure of telomeric DNA in three species of Baikal gastropods (Caenogastropoda: Hydrobioidea: Benedictiidae)].
[Markers of cellular senescence].
[Multiplex ligation-dependent probe amplification for detecting submicroscopic chromosomal abnormalities in Chinese children with global developmental delay or intellectual disability].
[Natural compounds--modulators of senescence and cell death].
[Possibilities of molecular genetic determination of age of an individual from biological traces].
[Preparation and identification of monoclonal antibody against repression and activation protein 1].
[Related factors of sperm DNA damage: Advances in studies].
[Research of anti-aging mechanism of ginsenoside Rg1 on brain].
[Senescence of mesothelial cells].
[Should a systematic fertility preservation be proposed to healthy women carrying a BRCA1/2 mutation?].
[Stem cells of umbilical blood cord - therapeutic use].
[Telomerase and telomere: their structure and dynamics in health and disease].
[Telomere length and Mediterranean diet - a clear association].
[Telomere length and telomerase mutations in peripheral blood leukocytes of children with chronic aplastic anemia].
[Telomere length and transrenal DNA isolated from transplanted kidney recipients' urine].
[Telomere length of peripheral lymphocytes in patients with immuno-related pancytopenia].
[Telomere maintenance by DNA damage sensor kinases, ATM and ATR].
[Telomeres and chronic heart failure].
[The study of telomere length in patients with Parkinson's disease].
[The telomere position effect: silence in the back row!].
1p34.2 rs621559 and 14q21 rs398652 leukocyte telomere length-related genetic variants contribute to glioma susceptibility.
2,6-diaminopurine nucleoside derivative of 9-ethyloxy-2-oxo-1,3-diazaphenoxazine (2-amino-Adap) for recognition of 8-oxo-dG in DNA.
21st Century Genetics: Mass Spectrometry of Yeast Telomerase.
25-Hydroxyvitamin D Concentration and Leukocyte Telomere Length in Young Adults: Findings From the Northern Finland Birth Cohort 1966.
2C.01: FIXED RANKING OF LEUKOCYTE TELOMERE LENGTH IN ELDERLY PEOPLE: RESULTS FROM 8 YEAR FOLLOW-UP OF THE ADELAHYDE COHORT.
5-aza-2'-deoxycytidine-mediated c-myc Down-regulation triggers telomere-dependent senescence by regulating human telomerase reverse transcriptase in chronic myeloid leukemia.
53BP1 and the LINC Complex Promote Microtubule-Dependent DSB Mobility and DNA Repair.
53BP1 mediates the fusion of mammalian telomeres rendered dysfunctional by DNA-PKcs loss or inhibition.
53BP1: pro choice in DNA repair.
A 'telomere-associated secretory phenotype' cooperates with BCR-ABL to drive malignant proliferation of leukemic cells.
A basal level of DNA damage and telomere deprotection increases the sensitivity of cancer cells to G-quadruplex interactive compounds.
A beginning of the end: new insights into the functional organization of telomeres.
A biobehavioral perspective on telomere length and the exposome.
A cascade leading to premature aging phenotypes including abnormal tumor profiles in Werner syndrome (review).
A case report on a rare disease: dyskeratosis congenita.
A cell-based model system links chromothripsis with hyperploidy.
A chemically defined medium-based strategy to efficiently generate clinically relevant cord blood mesenchymal stromal colonies.
A Common Cancer Risk-Associated Allele in the hTERT Locus Encodes a Dominant Negative Inhibitor of Telomerase.
A comparison of oncogene-induced senescence and replicative senescence: implications for tumor suppression and aging.
A comparison of replicative senescence and doxorubicin-induced premature senescence of vascular smooth muscle cells isolated from human aorta.
A correlation study of telomere length in peripheral blood leukocytes and kidney function with age.
A cross-sectional analysis of the association between perceived network social control and telomere length.
A crucial role for DOK1 in PDGF-BB-stimulated glioma cell invasion through p130Cas and Rap1 signalling.
A distinct type of heterochromatin at the telomeric region of the Drosophila melanogaster Y chromosome.
A DNA-hairpin model for repeat-addition processivity in telomere synthesis.
A dynamic meiotic SUN belt includes the zygotene-stage telomere bouquet and is disrupted in chromosome segregation mutants of maize (Zea mays L.).
A feasibility study of the association of exposure to biomass smoke with vascular function, inflammation, and cellular aging.
A gain-of-function senescence bypass screen identifies the homeobox transcription factor DLX2 as a regulator of ATM-p53 signaling.
A genome-wide association study identifies a locus on TERT for mean telomere length in Han Chinese.
A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.
A genomics approach identifies senescence-specific gene expression regulation.
A GWAS Meta-analysis and Replication Study Identifies a Novel Locus within CLPTM1L/TERT Associated with Nasopharyngeal Carcinoma in Individuals of Chinese Ancestry.
A high-resolution gene expression map of the Arabidopsis shoot meristem stem cell niche.
A higher-order entity formed by the flexible assembly of RAP1 with TRF2.
A human artificial chromosome recapitulates the metabolism of native telomeres in mammalian cells.
A human telomeric G-quadruplex-based electronic nanoswitch for the detection of anticancer drugs.
A loopy view of telomere evolution.
A meta-analytic review of the effects of mindfulness meditation on telomerase activity.
A model of a patient-derived IDH1 mutant anaplastic astrocytoma with alternative lengthening of telomeres.
A modified recombineering protocol for the genetic manipulation of gene clusters in Aspergillus fumigatus.
A mutation in the H/ACA box of telomerase RNA component gene (TERC) in a young patient with myelodysplastic syndrome.
A mutation in the POT1 gene is responsible for cardiac angiosarcoma in TP53-negative Li-Fraumeni-like families.
A Natural Product Telomerase Activator as Part of a Health Maintenance Program
A nested case-controlled comparison of telomere length and psychological functioning in breast cancer survivors with and without insomnia symptoms.
A new case of an inherited reciprocal translocation in cattle: rcp(13;26) (q24;q11).
A new der(1;7)(q10;p10) leading to a singular 1p loss in a case of glioblastoma with oligodendroglioma component.
A new mutant at the end: TPP1, telomeres, and BMF.
A new phosphorylated form of Ku70 identified in resistant leukemic cells confers fast but unfaithful DNA repair in cancer cell lines.
A new Riff: Rif1 eats its cake and has it too.
A newly identified berberine derivative induces cancer cell senescence by stabilizing endogenous G-quadruplexes and sparking a DNA damage response at the telomere region.
A non-canonical function of telomerase RNA in the regulation of developmental myelopoiesis in zebrafish.
A non-genetic, epigenetic-like mechanism of telomere length inheritance?
A Nonrandomized Trial of Progressive Resistance Training Intervention in Women With Polycystic Ovary Syndrome and Its Implications in Telomere Content.
A novel dyskerin (DKC1) mutation is associated with familial interstitial pneumonia.
A Novel Inositol Pyrophosphate Phosphatase in Saccharomyces cerevisiae: Siw14 PROTEIN SELECTIVELY CLEAVES THE β-PHOSPHATE FROM 5-DIPHOSPHOINOSITOL PENTAKISPHOSPHATE (5PP-IP5).
A novel somatic mutation in ACD induces telomere lengthening and apoptosis resistance in leukemia cells.
A novel telomerase substrate precursor rapidly induces telomere dysfunction in telomerase positive cancer cells but not telomerase silent normal cells.
A novel transchromosomic system: stable maintenance of an engineered Mb-sized human genomic fragment translocated to a mouse chromosome terminal region.
A Novel Type Pathway-Specific Regulator and Dynamic Genome Environments of a Solanapyrone Biosynthesis Gene Cluster in the Fungus Ascochyta rabiei.
A novel Werner Syndrome mutation: pharmacological treatment by read-through of nonsense mutations and epigenetic therapies.
A parallel quadruplex DNA is bound tightly but unfolded slowly by pif1 helicase.
A pathway approach to evaluating the association between the CHIEF pathway and risk of colorectal cancer.
A PCR-free fluorescence strategy for detecting telomerase activity via double amplification strategy.
A pilgrim's guide to G-quadruplex nucleic acid folding.
A Pilot Study of the Telomerase Inhibitor Imetelstat for Myelofibrosis.
A platform for rapid exploration of aging and diseases in a naturally short-lived vertebrate.
A Polyadenylation-Dependent 3' End Maturation Pathway Is Required for the Synthesis of the Human Telomerase RNA.
A possible new mechanism in the pathophysiology of polycystic ovary syndrome (PCOS): the discovery that leukocyte telomere length is strongly associated with PCOS.
A preclinical mouse model of glioma with an alternative mechanism of telomere maintenance (ALT).
A primary melanoma and its asynchronous metastasis highlight the role of BRAF, CDKN2A, and TERT.
A Prospective Study Investigating Prediagnostic Leukocyte Telomere Length and Risk of Developing Rheumatoid Arthritis in Women.
A prospective study of leukocyte telomere length and risk of phobic anxiety among women.
A proteomic perspective of Sirtuin 6 (SIRT6) phosphorylation and interactions and their dependence on its catalytic activity.
A randomized phase II study of the telomerase inhibitor imetelstat as maintenance therapy for advanced non-small-cell lung cancer.
A rare subtelomeric deletion syndrome: Wolf Hirschhorn syndrome.
A retrospective examination of mean relative telomere length in the Tasmanian Familial Hematological Malignancies Study.
A role for human mitochondrial complex II in the production of reactive oxygen species in human skin.
A role for Separase in telomere protection.
A second essential function of the Est1-binding arm of yeast telomerase RNA.
A selfish DNA element engages a meiosis-specific motor and telomeres for germ-line propagation.
A sequence-specific DNA binding small molecule triggers the release of immunogenic signals and phagocytosis in a model of B-cell lymphoma.
A SERS/fluorescence dual-mode nanosensor based on the human telomeric G-quadruplex DNA: Application to mercury (II) detection.
A shorter telomere is the key factor in preventing cultured human mesenchymal stem cells from senescence escape.
A simple "add and measure" FRET-based telomeric tandem repeat sequence detection and telomerase assay method.
A simple cytogenetic method to detect chromosomally integrated human herpesvirus-6.
A single-cell assay for telomere DNA content shows increasing telomere length heterogeneity, as well as increasing mean telomere length in human spermatozoa with advancing age.
A single-molecule force-spectroscopic study on stabilization of G-quadruplex DNA by a telomerase inhibitor.
A statistical approach to distinguish telomere elongation from error in longitudinal datasets.
A switch-like dynamic mechanism for the initiation of replicative senescence.
A test of biological and behavioral explanations for gender differences in telomere length: the multi-ethnic study of atherosclerosis.
A tight control of Rif1 by Oct4 and Smad3 is critical for mouse embryonic stem cell stability.
A TIN2 dyskeratosis congenita mutation causes telomerase-independent telomere shortening in mice.
A truncated hnRNP A1 isoform, lacking the RGG-box RNA binding domain, can efficiently regulate HIV-1 splicing and replication.
A two-step model for senescence triggered by a single critically short telomere
A unique inhibitor binding site in ERK1/2 is associated with slow binding kinetics.
A very rare case of trisomy 4q32.3-4q35.2 and trisomy 21q11.2-21q22.11 in a patient with recombinant chromosomes 4 and 21.
Aberrant reduction of telomere repetitive sequences in plasma cell-free DNA for early breast cancer detection.
Abrogation of Age-Induced MicroRNA-195 Rejuvenates the Senescent Mesenchymal Stem Cells by Reactivating Telomerase.
Absence of telomerase reverse transcriptase promoter mutations in neuroblastoma.
Absolute leukocyte telomere length in HIV-infected and uninfected individuals: evidence of accelerated cell senescence in HIV-associated chronic obstructive pulmonary disease.
Absolute qPCR for measuring telomere length in bone marrow samples of plasma cell disorders.
Accelerated methotrexate, vinblastine, doxorubicin, and cisplatin is safe, effective, and efficient neoadjuvant treatment for muscle-invasive bladder cancer: results of a multicenter phase II study with molecular correlates of response and toxicity.
Accelerated senescence of cord blood endothelial progenitor cells in premature neonates is driven by SIRT1 decreased expression.
Accelerated Telomere Erosion Is Associated with a Declining Immune Function of Caregivers of Alzheimer's Disease Patients
Accelerated telomere reduction and hepatocyte senescence in tolerated human liver allografts.
Accelerated Telomere Shortening in Acromegaly; IGF-I Induces Telomere Shortening and Cellular Senescence.
Accelerated telomere shortening in response to life stress
Accelerated telomere shortening in β-thalassemia/HbE patients.
Acquired TERT promoter mutations stimulate TERT transcription in mantle cell lymphoma.
Acrolein-exposed normal human lung fibroblasts in vitro: cellular senescence, enhanced telomere erosion, and degradation of werner's syndrome protein.
Acrylamide induces accelerated endothelial aging in a human cell model.
Activation of Telomerase by TA-65 Enhances Immunity and Reduces Inflammation Post Myocardial Infarction
Activation of tumor suppressor p53 gene expression by magnetic thymine-imprinted chitosan nanoparticles.
Activity of telomerase and telomeric length in Apis mellifera.
Acute dyskerin depletion triggers cellular senescence and renders osteosarcoma cells resistant to genotoxic stress-induced apoptosis.
Acute exercise leads to regulation of telomere-associated genes and microRNA expression in immune cells.
Acute myeloid leukemia arising from a donor derived premalignant hematopoietic clone: A possible mechanism for the origin of leukemia in donor cells.
Addition of bases to the 5'-end of human telomeric DNA: influences on thermal stability and energetics of unfolding.
Adipocyte telomere length associates negatively with adipocyte size, whereas adipose tissue telomere length associates negatively with the extent of fibrosis in severely obese women.
Adult stem cell and mesenchymal progenitor theories of aging.
Advances in the molecular design of potential anticancer agents via targeting of human telomeric DNA.
Adverse childhood experiences and leukocyte telomere maintenance in depressed and healthy adults.
Age intrinsic loss of telomere protection via TRF1 reduction in endothelial cells.
Age-associated change of C/EBP family proteins causes severe liver injury and acceleration of liver proliferation after CCl4 treatments.
Age-associated telomere attrition of lymphocytes in vivo is co-ordinated with changes in telomerase activity, composition of lymphocyte subsets and health conditions.
Age-related arterial telomere uncapping and senescence is greater in women compared with men.
Age-related declines and disease-associated variation in immune cell telomere length in a wild mammal.
Age-related declines in immune response in a wild mammal are unrelated to immune cell telomere length.
Age-Related Left Ventricular Changes and Their Association with Leukocyte Telomere Length in Healthy People.
Ageing and reproduction: antioxidant supplementation alleviates telomere loss in wild birds.
Ageing and the telomere connection: An intimate relationship with inflammation.
Ageing does not result in a decline in cell synthetic activity in an injury prone tendon.
Ageing induced vascular smooth muscle cell senescence in atherosclerosis.
Ageing mechanisms and associated lipid changes.
Ageing: Live faster, die younger.
aging
aging
Aging and HIV/AIDS: pathogenetic role of therapeutic side effects.
Aging and magnetism: Presenting a possible new holistic paradigm for ameliorating the aging process and the effects thereof, through externally applied physiologic PicoTesla magnetic fields.
Aging and potential for self-renewal: hydra living in the age of aging - a mini-review.
Aging and radiation: bad companions.
Aging and Systemic Lupus Erythematosus - Immunosenescence and Beyond.
Aging and uremia: Is there cellular and molecular crossover?
Aging as an optimization between cellular maintenance requirements and evolutionary constraints.
Aging as an Optimization between Cellular Maintenance Requirements and Evolutionary Constraints.
Aging Effects on Cardiac Progenitor Cell Physiology.
Aging in the Canine Kidney.
Aging of blood can be tracked by DNA methylation changes at just three CpG sites.
Aging of intrauterine tissues in spontaneous preterm birth and preterm premature rupture of the membranes: A systematic review of the literature.
Aging with ING: a comparative study of different forms of stress induced premature senescence.
Aging-Induced Stem Cell Mutations as Drivers for Disease and Cancer.
Aging-related systemic manifestations in COPD patients and cigarette smokers.
AKT activation and telomerase reverse transcriptase expression are concurrently associated with prognosis of gastric cancer.
AKT plays a crucial role in gastric cancer.
AKTIP/Ft1, a New Shelterin-Interacting Factor Required for Telomere Maintenance.
All-atomic simulations on human telomeric G-quadruplex DNA binding with thioflavin T.
Alleles of newly identified barley gene HvPARP3 exhibit changes in efficiency of DNA repair.
Allium telomeres unmasked: the unusual telomeric sequence (CTCGGTTATGGG)n is synthesized by telomerase.
Allogeneic hematopoietic stem cell transplantation for inherited bone marrow failure syndromes.
ALT telomeres get together with nuclear receptors.
Alteration of histone acetylation pattern during long-term serum-free culture conditions of human fetal placental mesenchymal stem cells.
Alterations in leukocyte telomere length in workers occupationally exposed to benzene.
Alterations of Mitochondrial DNA Copy Number and Telomere Length With Early Adversity and Psychopathology.
Alterations of telomere length and DNA methylation in hairdressers: A cross-sectional study.
Altered expression of genes associated with telomere maintenance and cell function of human vascular endothelial cell at elevated temperature.
Altered metabolic and stemness capacity of adipose tissue-derived stem cells from obese mouse and human.
Altered telomere homeostasis and resistance to skin carcinogenesis in Suv39h1 transgenic mice.
Alternative arrangements of telomeric recognition sites regulate the binding mode of the DNA-binding domain of yeast Rap1.
Alternative end-joining pathway(s): bricolage at DNA breaks.
Alternative lengthening of telomeres and loss of ATRX are frequent events in pleomorphic and dedifferentiated liposarcomas.
Alternative lengthening of telomeres in cancer stem cells in vivo.
Alternative lengthening of telomeres in neuroblastoma cell lines is associated with a lack of MYCN genomic amplification and with p53 pathway aberrations.
Alternative Lengthening of Telomeres is characterized by reduced compaction of telomeric chromatin.
Alternative lengthening of telomeres is enriched in, and impacts survival of TP53 mutant pediatric malignant brain tumors.
Alternative lengthening of telomeres phenotype in malignant vascular tumors is highly associated with loss of ATRX expression and is frequently observed in hepatic angiosarcomas.
Alternative lengthening of telomeres predicts site of origin in neuroendocrine tumor liver metastases.
Alternative lengthening of telomeres renders cancer cells hypersensitive to ATR inhibitors.
Alternative splicing regulation of telomerase: a new paradigm?
ALTernative Telomere Maintenance and Cancer.
Alzheimer's
Ambient air pollution, blood mitochondrial DNA copy number and telomere length in a panel of diabetes patients.
Ambient air pollution, blood mitochondrial DNA copy number and telomere length in a panel of diabetes patients.
An "enigmatic" L-carnosine (β-alanyl-L-histidine)? Cell proliferative activity as a fundamental property of a natural dipeptide inherent to traditional antioxidant, anti-aging biological activities: balancing and a hormonally correct agent, novel patente
An antiapoptotic role for telomerase RNA in human immune cells independent of telomere integrity or telomerase enzymatic activity.
An experimental demonstration that early-life competitive disadvantage accelerates telomere loss.
An in vitro expansion score for tissue-engineering applications with human bone marrow-derived mesenchymal stem cells.
An increase of oxidised nucleotides activates DNA damage checkpoint pathway that regulates post-embryonic development in Caenorhabditis elegans.
An intact putative mouse telomerase essential N-terminal domain is necessary for proper telomere maintenance.
An integrative review of factors associated with telomere length and implications for biobehavioral research.
An investigation of G-quadruplex structural polymorphism in the human telomere using a combined approach of hydrodynamic bead modeling and molecular dynamics simulation.
An Investigation on Mitochondrial DNA Deletions and Telomere Shortening during Multiple Passages of Adult Stem Cells.
Analysis of association among clinical features and shorter leukocyte telomere length in mitochondrial diabetes with m.3243A>G mitochondrial DNA mutation.
Analysis of invdupdel(8p) rearrangement: Clinical, cytogenetic and molecular characterization.
Analysis of meiosis in SUN1 deficient mice reveals a distinct role of SUN2 in mammalian meiotic LINC complex formation and function.
Analysis of poly(ADP-Ribose) polymerases in Arabidopsis telomere biology.
Analysis of telomerase activity based on a spired DNA tetrahedron TS primer.
Analysis of telomerase by the telomeric hemin/G-quadruplex-controlled aggregation of au nanoparticles in the presence of cysteine.
Analysis of telomere attrition in bipolar disorder.
Analysis of telomere length as predictive marker in psoriasis for comorbidities.
Analysis of the age of Panax ginseng based on telomere length and telomerase activity.
Anemia
Aneuploidy as a mechanism of adaptation to telomerase insufficiency.
Another facet to the anticancer response to lamellarin D: induction of cellular senescence through inhibition of topoisomerase I and intracellular Ros production.
Antagonistic roles for the ubiquitin ligase Asr1 and the ubiquitin-specific protease Ubp3 in subtelomeric gene silencing.
Anti-aging effect of estrogen on telomerase activity in ovariectomised rats--animal model for menopause.
Anti-Aging Implications of Astragalus Membranaceus (Huangqi): A Well-Known Chinese Tonic
Anti-leukemic effect of sodium metaarsenite (KML001) in acute myeloid leukemia with breaking-down the resistance of cytosine arabinoside.
Anti-tumoral effect of arsenic compound, sodium metaarsenite (KML001), in non-Hodgkin's lymphoma: an in vitro and in vivo study.
Anticancer activity for targeting telomeric G-quadruplex and antiangiogenesis of a novel Ru(II)-Se complex.
Antigenic variation in African trypanosomes.
Antioxidants safeguard telomeres in bold chicks.
Antiproliferative effect of the isoquinoline alkaloid papaverine in hepatocarcinoma HepG-2 cells--inhibition of telomerase and induction of senescence.
Antiretroviral therapy-induced toxicity is associated with increased mRNA expression of telomerase.
Antisense oligonucleotides targeting human telomerase mRNA increases the radiosensitivity of nasopharyngeal carcinoma cells.
Anxiety disorders and accelerated cellular ageing.
APE1 incision activity at abasic sites in tandem repeat sequences.
Application of flow-FISH for dynamic measurement of telomere length in cell division.
Applying molecular epidemiology in pediatric leukemia.
Architectural Clones in Aplastic Anaemia- Lessons Learned from High Throughput Sequencing.
Are Anxiety Disorders Associated with Accelerated Aging? A Focus on Neuroprogression.
Are short telomeres hallmarks of cancer recurrence?
Are the leukocyte telomere length attrition and telomerase activity alteration potential predictor biomarkers for sporadic TAA in aged individuals?
Arm-specific telomere dynamics of each individual chromosome in induced pluripotent stem cells revealed by quantitative fluorescence in situ hybridization.
Arsenic exposure through drinking water leads to senescence and alteration of telomere length in humans: A case-control study in West Bengal, India.
Arsenic exposure, telomere length, and expression of telomere-related genes among Bangladeshi individuals.
Arsenic trioxide inhibits glioma cell growth through induction of telomerase displacement and telomere dysfunction.
Arsenic trioxide suppresses transcription of hTERT through down-regulation of multiple transcription factors in HL-60 leukemia cells.
Artemisinin mimics calorie restriction to trigger mitochondrial biogenesis and compromise telomere shortening in mice.
Assembly of telomeric chromatin to create ALTernative endings.
Assessing telomere length using surface enhanced Raman scattering.
Assessment of gene promoter G‑quadruplex binding and modulation by a naphthalene diimide derivative in tumor cells.
Assessment of the clinical relevance of 17q25.3 copy number and three-dimensional telomere organization in non-small lung cancer patients.
Assessment of tumourigenic potential in long-term cryopreserved human adipose-derived stem cells.
Association between CLPTM1L-TERT rs401681 polymorphism and risk of pancreatic cancer: a meta-analysis.
Association between dietary patterns in the remote past and telomere length.
Association Between Donor Leukocyte Telomere Length and Survival After Unrelated Allogeneic Hematopoietic Cell Transplantation for Severe Aplastic Anemia
Association between donor leukocyte telomere length and survival after unrelated allogeneic hematopoietic cell transplantation for severe aplastic anemia.
Association between higher plasma lutein, zeaxanthin, and vitamin C concentrations and longer telomere length: results of the Austrian Stroke Prevention Study.
Association between informal caregiving and cellular aging in the survey of the health of wisconsin: the role of caregiving characteristics, stress, and strain.
Association between Kidney Function and Telomere Length: The Heart and Soul Study.
Association between leukocyte telomere length and bone mineral density in women 25-93 years of age.
Association between leukocyte telomere length and glioma risk: a case-control study.
Association Between Leukocyte Telomere Length and Plasma Homocysteine in a Singapore Chinese Population.
Association between leukocyte telomere length and serum carotenoid in US adults.
Association between leukocyte telomere length and vascular dementia and cancer mortality in an elderly population.
Association between Long Interspersed Nuclear Element-1 Methylation and Relative Telomere Length in Wilms Tumor.
Association Between Long Telomere Length and Insulin Sensitization in Adolescent Girls With Hyperinsulinemic Androgen Excess.
Association between maternal symptoms of sleep disordered breathing and fetal telomere length.
Association between previously identified loci affecting telomere length and coronary heart disease (CHD) in Han Chinese population.
Association between regulator of telomere elongation helicase 1 polymorphism and susceptibility to glioma.
Association between short leukocyte telomere length and HIV infection in a cohort study: No evidence of a relationship with antiretroviral therapy.
Association between short leukocyte telomere length, endotoxemia, and severe periodontitis in people with diabetes: a cross-sectional survey.
Association between shortened leukocyte telomere length and cardio-metabolic outcomes.
Association between shortened leukocyte telomere length and cardiometabolic outcomes: systematic review and meta-analysis.
Association Between Snoring and Leukocyte Telomere Length.
Association between telomere length and chromosome 21 nondisjunction in the oocyte.
Association between telomere length and survival in patients with idiopathic pulmonary fibrosis.
Association between telomere length in blood and mortality in people aged 60 years or older
Association Between Telomere Length, Specific Causes of Death, and Years of Healthy Life in Health, Aging, and Body Composition, a Population-Based Cohort Study
Association Between Telomere Length, Specific Causes of Death, and Years of Healthy Life in Health, Aging, and Body Composition, a Population-Based Cohort Study
Association between TERT rs2736100 polymorphism and lung cancer susceptibility: evidence from 22 case-control studies.
Association of adiponectin and leptin with relative telomere length in seven independent cohorts including 11,448 participants.
Association of BLM and BRCA1 during Telomere Maintenance in ALT Cells.
Association of dimensional psychological health measures with telomere length in male war veterans.
Association of genetic polymorphisms in the telomerase reverse transcriptase gene with prostate cancer aggressiveness.
Association of human papillomavirus with Fanconi anemia promotes carcinogenesis in Fanconi anemia patients.
Association of human telomerase reverse transcriptase gene polymorphisms, serum levels, and telomere length with renal cell carcinoma risk and pathology.
Association of Insulin Resistance, Arterial Stiffness and Telomere Length in Adults Free of Cardiovascular Diseases.
Association of leukocyte telomere length in peripheral blood leukocytes with endometrial cancer risk in Caucasian Americans.
Association of leukocyte telomere length with fatigue in nondisabled older adults.
Association of leukocyte telomere length with oxidative stress in yoga practitioners.
Association of relative telomere length with cardiovascular disease in a large chronic kidney disease cohort: the GCKD study.
Association of relative telomere length with progression of chronic kidney disease in two cohorts: effect modification by smoking and diabetes.
Association of telomere length and mitochondrial DNA copy number in a community sample of healthy adults.
Association of telomere length and mitochondrial DNA copy number with risperidone treatment response in first-episode antipsychotic-naïve schizophrenia.
Associations between early life stress, self-reported traumatic experiences across the lifespan and leukocyte telomere length in elderly adults.
Associations between socioeconomic status, aging and functionality among older women.
Associations between the five-factor model of personality and leukocyte telomere length in elderly men and women: The Helsinki Birth Cohort Study (HBCS).
Associations between the rs6010620 polymorphism in RTEL1 and risk of glioma: a meta-analysis of 20,711 participants.
Associations of Buccal Cell Telomere Length with Daily Intake of β-Carotene or α-Tocopherol Are Dependent on Carotenoid Metabolism-related Gene Polymorphisms in Healthy Japanese Adults.
Associations of cadmium and lead exposure with leukocyte telomere length: findings from National Health and Nutrition Examination Survey, 1999-2002.
Associations of ghrelin with eating behaviors, stress, metabolic factors, and telomere length among overweight and obese women: preliminary evidence of attenuated ghrelin effects in obesity?
Associations of TERC Single Nucleotide Polymorphisms with Human Leukocyte Telomere Length and the Risk of Type 2 Diabetes Mellitus.
At short telomeres Tel1 directs early replication and phosphorylates Rif1.
ATG-induced accelerated immune senescence: clinical implications in renal transplant recipients.
atherosclerosis
ATM and ATR Signaling Regulate the Recruitment of Human Telomerase to Telomeres.
ATM Inhibition Potentiates Death of Androgen Receptor-inactivated Prostate Cancer Cells with Telomere Dysfunction.
ATM Kinase Is Required for Telomere Elongation in Mouse and Human Cells.
ATM regulates insulin-like growth factor 1-secretory clusterin (IGF-1-sCLU) expression that protects cells against senescence.
Atorvastatin induces T cell proliferation by a telomerase reverse transcriptase (TERT) mediated mechanism.
ATRX dysfunction induces replication defects in primary mouse cells.
ATRX Plays a Key Role in Maintaining Silencing at Interstitial Heterochromatic Loci and Imprinted Genes.
ATRX represses alternative lengthening of telomeres.
Augmented telomerase activity, reduced telomere length and the presence of alternative lengthening of telomere in renal cell carcinoma: plausible predictive and diagnostic markers.
Aurora B prevents chromosome arm separation defects by promoting telomere dispersion and disjunction.
Aurora Kinase B Regulates Telomerase Activity via a Centromeric RNA in Stem Cells.
Automated Assay of Telomere Length Measurement and Informatics for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort.
Autophagy-independent senescence and genome instability driven by targeted telomere dysfunction.
Autosomal ring chromosomes in human genetic disorders.
Balancing self-renewal against genome preservation in stem cells: How do they manage to have the cake and eat it too?
Baseline biopsychosocial determinants of telomere length and 6-year attrition rate.
Behavior of replication origins in Eukaryota - spatio-temporal dynamics of licensing and firing.
Beneficial Effects of Telomerase Activator (TA-65) Against Cancer
Beneficial Effects of Telomerase Activator (TA-65) Against Cardiovascular Disease
Beneficial Effects of Telomerase Activator (TA-65) Against Metabolic Syndrome
Beneficial Effects of Telomerase Activator (TA-65) Against Neurobiology
Beneficial Effects of Telomerase Activator (TA-65) Against Telomere Length
Beneficial Effects of Telomerase Activator (TA-65) Against Vision
Benzo(a)pyrene disrupts mouse preimplantation embryo development.
Bimolecular Fluorescence Complementation (BiFC) Analysis: Advances and Recent Applications for Genome-Wide Interaction Studies.
Binding of Multiple Rap1 Proteins Stimulates Chromosome Breakage Induction during DNA Replication.
Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation.
Binding of TPP1 protein to TIN2 protein is required for POT1a,b protein-mediated telomere protection.
Binding polarity of RPA to telomeric sequences and influence of G-quadruplex stability.
Biologic function and clinical potential of telomerase and associated proteins in cardiovascular tissue repair and regeneration
Biological ageing and frailty markers in breast cancer patients.
Biological differential diagnosis of follicular thyroid tumor and Hürthle cell tumor on the basis of telomere length and hTERT expression.
Biological effects of in vitro THz radiation exposure in human foetal fibroblasts.
Biology of cancer and aging: a complex association with cellular senescence.
Biology of telomeres: lessons from budding yeast.
Biology. Malaria may accelerate aging in birds.
Biomarkers of oxidative stress and cataract. Novel drug delivery therapeutic strategies targeting telomere reduction and the expression of telomerase activity in the lens epithelial cells with N-acetylcarnosine lubricant eye drops: anti-cataract which hel
Biomarkers of progression of chronic obstructive pulmonary disease (COPD).
Biomolecular bases of the senescence process and cancer. A new approach to oncological treatment linked to ageing.
Biomolecular Markers Within the Core Axis of Aging and Particulate Air Pollution Exposure in the Elderly: A Cross-Sectional Study.
Biosafety evidence for human dedifferentiated adipocytes.
Blockade of senescence-associated microRNA-195 in aged skeletal muscle cells facilitates reprogramming to produce induced pluripotent stem cells.
Blood cell telomere lengths and shortening rates of chimpanzee and human females.
Blood Telomere Length Attrition and Cancer Development in the Normative Aging Study Cohort.
BnaC9.SMG7b Functions as a Positive Regulator of the Number of Seeds per Silique in Brassica napus by Regulating the Formation of Functional Female Gametophytes.
Body mass index and leukocyte telomere length dynamics among older adults: Results from the ESTHER cohort.
Body mass index and leukocyte telomere length in adults: a systematic review and meta-analysis.
Body weight status and telomere length in U.S. middle-aged and older adults.
Boldine, a natural aporphine alkaloid, inhibits telomerase at non-toxic concentrations.
Bone cell senescence: mechanisms and perspectives.
Bone marrow failure and the telomeropathies.
Bone marrow skeletal stem/progenitor cell defects in dyskeratosis congenita and telomere biology disorders.
Bone Marrow Stromal Cell (BMSC) and skeletal aging: role of telomerase enzyme.
Bortezomib-mediated down-regulation of telomerase and disruption of telomere homeostasis contributes to apoptosis of malignant cells.
BRAF mutation and CDKN2A deletion define a clinically distinct subgroup of childhood secondary high-grade glioma.
brain
Brain derived neurotrophic factor in the retina of the teleost N. furzeri.
BRCA1 and CtIP promote alternative non-homologous end-joining at uncapped telomeres.
BRCA1/2 mutations perturb telomere biology: characterization of structural and functional abnormalities in vitro and in vivo.
Break-induced replication requires DNA damage-induced phosphorylation of Pif1 and leads to telomere lengthening.
Breaking an epigenetic chromatin switch: curious features of hysteresis in Saccharomyces cerevisiae telomeric silencing.
Breaking new ground: digging into TERRA function.
Breast primary epithelial cells that escape p16-dependent stasis enter a telomere-driven crisis state.
BXSB-type genome causes murine autoimmune glomerulonephritis: pathological correlation between telomeric region of chromosome 1 and Yaa.
c-Kit-positive cardiac stem cells nested in hypoxic niches are activated by stem cell factor reversing the aging myopathy.
c-Myc quadruplex-forming sequence Pu-27 induces extensive damage in both telomeric and nontelomeric regions of DNA.
C. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency.
Ca²⁺-regulated secretory granule exocytosis in pancreatic and parotid acinar cells.
Calorie restriction and NAD⁺/sirtuin counteract the hallmarks of aging.
Calorie restriction increases telomerase activity, enhances autophagy, and improves diastolic dysfunction in diabetic rat hearts.
Can the TLR-4-mediated signaling pathway be "a key inflammatory promoter for sporadic TAA"?
cancer
Cancer-associated TERT promoter mutations abrogate telomerase silencing.
Cancer. TERT promoter mutations and telomerase reactivation in urothelial cancer.
Canine Mesenchymal Stem Cell Potential and the Importance of Dog Breed: Implication for Cell-Based Therapies.
Cardiac autonomic modulation, C-reactive protein or telomere length: which of these variables has greater importance to aging?
Cardiorespiratory Capacity and Leukocyte Telomere Length Among Adults in the United States.
cardiovascular
Carefully thinking about telomeres.
Carotid ultrasound examination as an aging and disability marker.
Cascades of genetic instability resulting from compromised break-induced replication.
CASE RECORDS of the MASSACHUSETTS GENERAL HOSPITAL. Case 41-2015. A 14-Year-Old Boy with Immune and Liver Abnormalities.
CASFISH: CRISPR/Cas9-mediated in situ labeling of genomic loci in fixed cells.
Catalytically active telomerase holoenzyme is assembled in the dense fibrillar component of the nucleolus during S phase.
Causes of genome instability: the effect of low dose chemical exposures in modern society.
Ccq1-Tpz1TPP1 interaction facilitates telomerase and SHREC association with telomeres in fission yeast.
CDC28 phosphorylates Cac1p and regulates the association of chromatin assembly factor I with chromatin.
Cdk1 regulates the temporal recruitment of telomerase and Cdc13-Stn1-Ten1 complex for telomere replication.
CDK2 regulates nuclear envelope protein dynamics and telomere attachment in mouse meiotic prophase.
cDNA Library Screening Identifies Protein Interactors Potentially Involved in Non-Telomeric Roles of Arabidopsis Telomerase.
Cell aging in relation to stress arousal and cardiovascular disease risk factors
Cell biology of disease: Telomeropathies: an emerging spectrum disorder.
Cell cycle control (and more) by programmed -1 ribosomal frameshifting: implications for disease and therapeutics.
Cell death during crisis is mediated by mitotic telomere deprotection.
Cell populations can use aneuploidy to survive telomerase insufficiency.
Cell senescence: role in aging and age-related diseases.
Cell therapy from bench to bedside: Hepatocytes from fibroblasts - the truth and myth of transdifferentiation.
Cell-based therapies of liver diseases: age-related challenges.
Cell-free DNA and telomere length among women undergoing in vitro fertilization treatment.
Cell-Free Fetal DNA, Telomeres, and the Spontaneous Onset of Parturition.
Cellular aging and restorative processes: subjective sleep quality and duration moderate the association between age and telomere length in a sample of middle-aged and older adults.
Cellular aging in depression: Permanent imprint or reversible process?: An overview of the current evidence, mechanistic pathways, and targets for interventions.
Cellular aging of skeletal muscle: telomeric and free radical evidence that physical inactivity is responsible and not age.
Cellular and molecular biology of aging endothelial cells.
Cellular and molecular mechanisms of statins: an update on pleiotropic effects.
Cellular functions of the dual-targeted catalytic subunit of telomerase, telomerase reverse transcriptase--potential role in senescence and aging.
Cellular senescence and aging: the role of B-MYB.
Cellular Senescence and Inflammatory Burden as Determinants of Mortality in Elderly People Until the Extreme old age.
Cellular Senescence as the Causal Nexus of Aging.
Cellular senescence in ageing, age-related disease and longevity.
Cellular senescence: a hitchhiker's guide.
Cellular senescence: when bad things happen to good cells
Centromere and telomere sequence alterations reflect the rapid genome evolution within the carnivorous plant genus Genlisea.
Centrosome aberrations in human mammary epithelial cells driven by cooperative interactions between p16INK4a deficiency and telomere-dependent genotoxic stress.
CEP63 deficiency promotes p53-dependent microcephaly and reveals a role for the centrosome in meiotic recombination.
Cerebro-retinal microangiopathy with calcifications and cysts due to recessive mutations in the CTC1 gene.
CGGBP1 phosphorylation constitutes a telomere-protection signal.
Change in peripheral blood leukocyte telomere length and mortality in breast cancer survivors.
Change in the telomere length distribution with age in the Japanese population
Change in the telomere length distribution with age in the Japanese population
Changes in DNA methylation patterns and repetitive sequences in blood lymphocytes of aged horses.
Changes in markers of oxidative stress and DNA damage in human visceral adipose tissue from subjects with obesity and type 2 diabetes.
Changes in telomere length distribution in low-dose X-ray-irradiated human umbilical vein endothelial cells.
Characterisation of an unusual telomere motif (TTTTTTAGGG)n in the plant Cestrum elegans (Solanaceae), a species with a large genome.
Characterization of a plant (rice) translin and its comparative analysis with human translin.
Characterization of fetal keratinocytes, showing enhanced stem cell-like properties: a potential source of cells for skin reconstruction.
Characterization of population-based variation and putative functional elements for the multiple-cancer susceptibility loci at 5p15.33.
Characterization of potassium binding with human telomeres.
Characterization of recombinants of the Aegilops peregrina-derived Lr59 translocation of common wheat.
Characterization of Skin Aging-Associated Secreted Proteins (SAASP) Produced by Dermal Fibroblasts Isolated from Intrinsically Aged Human Skin.
Characterization of the antioxidant systems in different complementation groups of Dyskeratosis Congenita.
Charting the "Splice" Routes to MDS.
Childhood Conscientiousness and Leukocyte Telomere Length 40 Years Later in Adult Women--Preliminary Findings of a Prospective Association.
Childhood Physical and Sexual Abuse History and Leukocyte Telomere Length among Women in Middle Adulthood.
Chimeric bifunctional oligonucleotides as a novel tool to invade telomerase assembly.
CHK1-driven histone H3.3 serine 31 phosphorylation is important for chromatin maintenance and cell survival in human ALT cancer cells.
Chk2 and p53 regulate the transmission of healed chromosomes in the Drosophila male germline.
Chondrogenic potential and anti-senescence effect of hypoxia on canine adipose mesenchymal stem cells.
Chromatin and beyond: the multitasking roles for SIRT6.
Chromatin interaction analysis reveals changes in small chromosome and telomere clustering between epithelial and breast cancer cells.
Chromatin organization and remodeling of interstitial telomeric sites during meiosis in the Mongolian gerbil (Meriones unguiculatus).
Chromatin regulation of DNA damage repair and genome integrity in the central nervous system.
Chromosomal instability and telomere shortening in long-term culture of hematopoietic stem cells: insights from a cell culture model of RPS14 haploinsufficiency.
Chromosomal instability--mechanisms and consequences.
Chromosomal mapping of repetitive DNAs in Triportheus trifurcatus (Characidae, Characiformes): insights into the differentiation of the Z and W chromosomes.
Chromosomal polymorphism in Rineloricaria lanceolata Günther, 1868 (Loricariidae: Loricariinae) of the Paraguay basin (Mato Grosso do Sul, Brazil): evidence of fusions and their consequences in the population.
Chromosomal structures and repetitive sequences divergence in Cucumis species revealed by comparative cytogenetic mapping.
Chromosomally integrated HHV-6: impact on virus, cell and organismal biology.
Chromosome banding in Amphibia. XXXI. The neotropical anuran families Centrolenidae and Allophrynidae.
Chromosome biology: Short telomeres can't reach.
Chromosome length and perinuclear attachment constrain resolution of DNA intertwines.
Chromosomes rein back the spindle pole body during horsetail movement in fission yeast meiosis.
Chromothripsis and Kataegis Induced by Telomere Crisis.
Chromothripsis-like patterns are recurring but heterogeneously distributed features in a survey of 22,347 cancer genome screens.
Chromothripsis: how does such a catastrophic event impact human reproduction?
Chromothripsis: potential origin in gametogenesis and preimplantation cell divisions. A review.
Chronic alcohol binging injures the liver and other organs by reducing NAD(+) levels required for sirtuin's deacetylase activity.
Chronic alcohol increases CD8+ T-cell immunosenescence in simian immunodeficiency virus-infected rhesus macaques.
Chronic and acute effects of endurance training on telomere length.
Chronic Hepatitis B Virus Infection: The Relation between Hepatitis B Antigen Expression, Telomere Length, Senescence, Inflammation and Fibrosis.
Chronic infection. Hidden costs of infection: chronic malaria accelerates telomere degradation and senescence in wild birds.
Chronic inflammation and angiogenic signaling axis impairs differentiation of dental-pulp stem cells.
Chronic inflammation induces telomere dysfunction and accelerates ageing in mice.
Chronic inflammation reduces cardiac relative telomere length without altering left ventricular chamber function.
Chronic kidney disease and premature ageing of the adaptive immune response.
Chronic replicative stress induced by CCl4 in TRF1 knockout mice recapitulates the origin of large liver cell changes.
Chronographic Theory of Development, Aging, and Origin of Cancer: Role of Chronomeres and Printomeres.
Chronographic theory of development, aging, and origin of cancer: role of chronomeres and printomeres.
Circadian desynchronization triggers premature cellular aging in a diurnal rodent.
Circular permutation of a synthetic eukaryotic chromosome with the telomerator.
Circulating leukocyte telomere length and risk of overall and aggressive prostate cancer.
Clinical features of ATRX or DAXX mutated neuroblastoma.
Clinical outcomes of lung transplant recipients with telomerase mutations.
Clinical Relevance of Telomere Status and Telomerase Activity in Colorectal Cancer.
Clinical utility gene card for: Dyskeratosis congenita - update 2015.
Clinical-scale in vitro expansion preserves biological characteristics of cardiac atrial appendage stem cells.
Clinico-Pathological Correlation of β-Catenin and Telomere Dysfunction in Head and Neck Squamous Cell Carcinoma Patients.
Clipping of Telomere from Human Chromosomes Using a Chemistry-Based Artificial Restriction DNA Cutter.
Cloning and molecular characterization of telomerase reverse transcriptase (TERT) and telomere length analysis of Peromyscus leucopus.
CNIO scientists successfully test the first gene therapy against aging-associated decline
Cognitive impairment, genomic instability and trace elements.
Cohort Profile: The Mexican American Mano a Mano Cohort.
Cold-inducible RNA-binding protein CIRP/hnRNP A18 regulates telomerase activity in a temperature-dependent manner.
Colorimetry and SERS dual-mode detection of telomerase activity: combining rapid screening with high sensitivity.
Combinatorial recognition of a complex telomere repeat sequence by the Candida parapsilosis Cdc13AB heterodimer.
Combined effects of leukocyte telomere length, p53 polymorphism and human papillomavirus infection on esophageal squamous cell carcinoma in a Han Chinese population.
Combined MYC Activation and Pten Loss Are Sufficient to Create Genomic Instability and Lethal Metastatic Prostate Cancer.
Combining FISH and model-based predictions to understand chromosome evolution in Typhonium (Araceae).
Commentary: Does mortality from smoking have implications for future Mendelian randomization studies?
Commentary: The reliability of telomere length measurements.
Common and low-frequency variants associated with genome-wide recombination rate.
Common telomerase reverse transcriptase promoter mutations in hepatocellular carcinomas from different geographical locations.
Comparative analysis of enzymatically produced novel linear DNA constructs with plasmids for use as DNA vaccines.
Comparative analysis of genome maintenance genes in naked mole rat, mouse, and human.
Comparative cytogenetics of six Indo-Pacific moray eels (Anguilliformes: Muraenidae) by chromosomal banding and fluorescence in situ hybridization.
Comparative cytogenomics of poultry: mapping of single gene and repeat loci in the Japanese quail (Coturnix japonica).
Comparative genomic analysis reveals occurrence of genetic recombination in virulent Cryptosporidium hominis subtypes and telomeric gene duplications in Cryptosporidium parvum.
Comparing genotoxic signatures in cord blood cells from neonates exposed in utero to zidovudine or tenofovir.
Comparison between southern blots and qPCR analysis of leukocyte telomere length in the health ABC study.
Comparison of Signaling Pathways Gene Expression in CD34(-) Umbilical Cord Blood and Bone Marrow Stem Cells.
Comparison of telomere length between population-specific mitochondrial haplogroups among different age groups in a Latvian population.
Comparison of telomere length in black and white teachers from South Africa: the sympathetic activity and ambulatory blood pressure in Africans study.
Comparison of the relative telomere length measured in leukocytes and eleven different human tissues.
Competing endogenous RNA and interactome bioinformatic analyses on human telomerase.
Complete genome sequence of Borrelia afzelii K78 and comparative genome analysis.
Complete sequence analysis of mitochondrial DNA and telomere length in aplastic anemia.
Compound heterozygous CORO1A mutations in siblings with a mucocutaneous-immunodeficiency syndrome of epidermodysplasia verruciformis-HPV, molluscum contagiosum and granulomatous tuberculoid leprosy.
Comprehensive evaluation of the immune risk phenotype in successfully treated HIV-infected individuals.
Compromised telomere maintenance in hypomethylated Arabidopsis thaliana plants.
Computel: computation of mean telomere length from whole-genome next-generation sequencing data.
Concentration-dependent exchange of replication protein A on single-stranded DNA revealed by single-molecule imaging.
Concise review: Genomic instability in human stem cells: current status and future challenges.
Conserved Telomere Length in Human Ectopic Thyroids: An Argument Against Premature Differentiation Causing Arrested Migration.
Construction and characterization of a Borrelia burgdorferi strain with conditional expression of the essential telomere resolvase, ResT.
Contrasting behavior of heterochromatic and euchromatic chromosome portions and pericentric genome separation in pre-bouquet spermatocytes of hybrid mice.
Contributions of the TEL-patch amino acid cluster on TPP1 to telomeric DNA synthesis by human telomerase.
Control of cell replication during aging.
Control of telomerase action at human telomeres.
Controversy in myocardial regeneration.
Conventional anticancer therapeutics and telomere maintenance mechanisms.
Coordinated DNA dynamics during the human telomerase catalytic cycle.
Coordination of transposon expression with DNA replication in the targeting of telomeric retrotransposons in Drosophila.
Cord blood telomere length in Latino infants: relation with maternal education and infant sex.
Cornelia de Lange syndrome: further delineation of phenotype, cohesin biology and educational focus, 5th Biennial Scientific and Educational Symposium abstracts.
Correction: Chronic Hepatitis B Virus Infection: The Relation between Hepatitis B Antigen Expression, Telomere Length, Senescence, Inflammation and Fibrosis.
Correction: Inhibition of Telomere Recombination by Inactivation of KEOPS Subunit Cgi121 Promotes Cell Longevity.
Correlation between terminal restriction fragments and flow-FISH measures in samples over wide range telomere lengths.
Correlations of telomere length, P53 mutation, and chromosomal translocation in soft tissue sarcomas.
Cortisol is not associated with telomere shortening or chromosomal instability in human lymphocytes cultured under low and high folate conditions.
Coupling Aging Immunity with a Sedentary Lifestyle: Has the Damage Already Been Done?
CRISPR/Cas9 mediated multiplex genome editing and heritable mutagenesis of BmKu70 in Bombyx mori.
Cross talk between EBV and telomerase: the role of TERT and NOTCH2 in the switch of latent/lytic cycle of the virus.
Cross-Sectional Associations between Exposure to Persistent Organic Pollutants and Leukocyte Telomere Length among U.S. Adults in NHANES, 2001-2002.
Crosstalk between telomere maintenance and radiation effects: A key player in the process of radiation-induced carcinogenesis.
Cryopreservation effects on Wharton's Jelly Stem Cells proteome.
Crystal structures of the Gon7/Pcc1 and Bud32/Cgi121 complexes provide a model for the complete yeast KEOPS complex.
CTC1 increases the radioresistance of human melanoma cells by inhibiting telomere shortening and apoptosis.
CUDR promotes liver cancer stem cell growth through upregulating TERT and C-Myc.
Cumulative PM(2.5) exposure and telomere length in workers exposed to welding fumes.
Cumulative stress in research animals: Telomere attrition as a biomarker in a welfare context?
Current insights into inherited bone marrow failure syndromes.
Cycling with BRCA2 from DNA repair to mitosis.
Cycloastragenol Is A Potent Telomerase Activator In Neuronal Cells: Implications For Depression Management
Cytogenetic analysis and chromosomal characteristics of the polymorphic 18S rDNA of Haliotis discus hannai from Fujian, China.
Cytogenetic heterogeneity and their serial dynamic changes during acquisition of cytogenetic aberrations in cultured mesenchymal stem cells.
Cytogenetic studies on Gonatodes (Reptilia, Squamata, Sphaerodactylidae).
Cytokinesis breaks dicentric chromosomes preferentially at pericentromeric regions and telomere fusions.
DCAF4, a novel gene associated with leucocyte telomere length.
De novo case of a partial trisomy 4p and a partial monosomy 8p.
Deactivation of Telomerase Enzyme and Telomere Destabilization by Natural Products: a Potential Target for Cancer Green Therapy.
Decreased cell proliferation and higher oxidative stress in fibroblasts from Down Syndrome fetuses. Preliminary study.
Decreased telomere length in metaphase and interphase cells from newborns with trisomy 21.
Decreasing initial telomere length in humans intergenerationally understates age-associated telomere shortening.
Defective proliferative potential of MSCs from pediatric myelodysplastic syndrome patients is associated with cell senescence.
Defective repair of uracil causes telomere defects in mouse hematopoietic cells.
Defects in subventricular zone pigmented epithelium-derived factor niche signaling in the senescence-accelerated mouse prone-8.
Deficiency of the Arabidopsis helicase RTEL1 triggers a SOG1-dependent replication checkpoint in response to DNA cross-links.
Definition of the cattle killer cell Ig-like receptor gene family: comparison with aurochs and human counterparts.
Delay discounting, genetic sensitivity, and leukocyte telomere length.
dementia
Dendrimer-like polymeric DNAs as chemiluminescence probes for amplified detection of telomere DNA on a solid-phase membrane.
Deoxyribonucleotide metabolism, mutagenesis and cancer.
Deoxyribonucleotides as genetic and metabolic regulators.
Depletion of SIRT6 causes cellular senescence, DNA damage, and telomere dysfunction in human chondrocytes.
Depletion of sirtuin 1 (SIRT1) leads to epigenetic modifications of telomerase (TERT) gene in hepatocellular carcinoma cells.
Depression and telomere length: A meta-analysis.
Depression Gets Old Fast: Do Stress and Depression Accelerate Cell Aging?
Depression, anxiety and telomere length in young adults: evidence from the National Health and Nutrition Examination Survey.
Depressive symptoms and short telomere length are associated with increased mortality in bladder cancer patients.
Design and synthesis of a new dimeric xanthone derivative: enhancement of G-quadruplex selectivity and telomere damage.
Detecting ATM-dependent chromatin modification in DNA damage response.
Detection and automated scoring of dicentric chromosomes in nonstimulated lymphocyte prematurely condensed chromosomes after telomere and centromere staining.
Detection of telomerase activity using microchip electrophoresis.
Determinants of telomere attrition over 1 year in healthy older women: stress and health behaviors matter.
Determination of Arabidopsis thaliana telomere length by PCR.
Development and validation of risk index for cognitive decline using blood-derived markers.
Development of a robust DNA damage model including persistent telomere-associated damage with application to secondary cancer risk assessment.
Developmental and familial predictors of adult cognitive traits in the European starling.
Developmental ORIgins of Healthy and Unhealthy AgeiNg: the role of maternal obesity--introduction to DORIAN.
Developmental telomere attrition predicts impulsive decision-making in adult starlings.
Dgcr8 and Dicer are essential for sex chromosome integrity during meiosis in males.
Diagnosis and treatment of pediatric acquired aplastic anemia (AAA): an initial survey of the North American Pediatric Aplastic Anemia Consortium (NAPAAC).
Diet and Inflammation: Possible Effects on Immunity, Chronic Diseases, and Life Span.
Diet, age, and prior injury status differentially alter behavioral outcomes following concussion in rats.
Dietary inflammatory index and telomere length in subjects with a high cardiovascular disease risk from the PREDIMED-NAVARRA study: cross-sectional and longitudinal analyses over 5 y.
Dietary intake alters behavioral recovery and gene expression profiles in the brain of juvenile rats that have experienced a concussion.
Dietary restriction ameliorates haematopoietic ageing independent of telomerase, whilst lack of telomerase and short telomeres exacerbates the ageing phenotype.
Dietary restriction mitigates age-related accumulation of DNA damage, but not all changes in mouse corneal epithelium.
Dietary total antioxidant capacity is associated with leukocyte telomere length in a children and adolescent population.
Different TP53 mutations are associated with specific chromosomal rearrangements, telomere length changes, and remodeling of the nuclear architecture of telomeres.
Differential amplification of satellite PaB6 in chromosomally hypervariable Prospero autumnale complex (Hyacinthaceae).
Differential effects of the extracellular microenvironment on human embryonic stem cell differentiation into keratinocytes and their subsequent replicative life span.
Differential Expression of Non-Shelterin Genes Associated with High Telomerase Levels and Telomere Shortening in Plasma Cell Disorders.
Differential localisation of PARP-1 N-terminal fragment in PARP-1(+/+) and PARP-1(-/-) murine cells.
Differential nuclear ATRX expression in sarcomas.
Differential Regulation of Telomerase Reverse Transcriptase Promoter Activation and Protein Degradation by Histone Deacetylase Inhibition.
Differential senescence capacities in meibomian gland carcinoma and basal cell carcinoma.
Differential sensitivity of telomerase from human hematopoietic stem cells and leukemic cell lines to mild hyperthermia.
Differential Telomere Shortening in Blood versus Arteries in an Animal Model of Type 2 Diabetes.
Differential timing of oxidative DNA damage and telomere shortening in hepatitis C and B virus-related liver carcinogenesis.
Diminazene or berenil, a classic duplex minor groove binder, binds to G-quadruplexes with low nanomolar dissociation constants and the amidine groups are also critical for G-quadruplex binding.
Direct comparison of flow-FISH and qPCR as diagnostic tests for telomere length measurement in humans.
Direct evaluation of myocardial viability and stem cell engraftment demonstrates salvage of the injured myocardium.
Direct fluorescence in situ hybridization on human metaphase chromosomes using quantum dot-platinum labeled DNA probes.
Direct observation of the dual-switching behaviors corresponding to the state transition in a DNA nanoframe.
Discovery of a structural-element specific G-quadruplex "light-up" probe.
Discovery of selective ligands for telomeric RNA G-quadruplexes (TERRA) through 19F-NMR based fragment screening.
Discovery-based protein expression profiling identifies distinct subgroups and pathways in leiomyosarcomas.
Discrimination between 8-oxo-2'-deoxyguanosine and 2'-deoxyguanosine in DNA by the single nucleotide primer extension reaction with adap triphosphate.
Discrimination, mental health, and leukocyte telomere length among African American men.
Discrimination, racial bias, and telomere length in African-American men.
Discussion.
Disease mutant analysis identifies a new function of DAXX in telomerase regulation and telomere maintenance.
Disposable Soma Theory and the Evolution of Maternal Effects on Ageing.
Disrupted lymphocyte homeostasis in hepatitis-associated acquired aplastic anemia is associated with short telomeres.
Disruption of Wnt/β-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells.
Dissecting Fission Yeast Shelterin Interactions via MICro-MS Links Disruption of Shelterin Bridge to Tumorigenesis.
Dissection of the cord blood stromal component reveals predictive parameters for culture outcome.
Distance-based assessment of the localization of functional annotations in 3D genome reconstructions.
Distribution of 18S rDNA sites and absence of the canonical TTAGG insect telomeric repeat in parasitoid Hymenoptera.
Distribution of telomeres in the tobacco meiotic nuclei during cytomixis.
Distribution of TTAGG-specific telomerase activity in insects.
Diversity and evolution of transposable elements in Arabidopsis.
DNA 'Telomere' Length Tied to Aging, Death Risk
DNA and RNA quadruplex-binding proteins.
DNA damage and lamins.
DNA damage in non-communicable diseases: A clinical and epidemiological perspective.
DNA damage markers in dermal fibroblasts in vitro reflect chronological donor age.
DNA damage response at telomeres contributes to lung aging and chronic obstructive pulmonary disease.
DNA double strand break responses and chromatin alterations within the aging cell.
DNA double-strand breaks and telomeres play important roles in trypanosoma brucei antigenic variation.
DNA methylation and healthy human aging.
DNA methylation in PRDM8 is indicative for dyskeratosis congenita.
DNA methylation of human telomerase reverse transcriptase associated with leukocyte telomere length shortening in hyperhomocysteinemia-type hypertension in humans and in a rat model.
DNA recombination. Recombination initiation maps of individual human genomes.
DNA repair defects and genome instability in Hutchinson-Gilford Progeria Syndrome.
DNA repair pathway selection caused by defects in TEL1, SAE2, and de novo telomere addition generates specific chromosomal rearrangement signatures.
DNA repair: Familiar ends with alternative endings.
DNA sequences proximal to human mitochondrial DNA deletion breakpoints prevalent in human disease form G-quadruplexes, a class of DNA structures inefficiently unwound by the mitochondrial replicative Twinkle helicase.
DNA-damage-induced type I interferon promotes senescence and inhibits stem cell function.
DNA-Directed Polymerase Subunits Play a Vital Role in Human Telomeric Overhang Processing.
DNA-PKcs phosphorylates hnRNP-A1 to facilitate the RPA-to-POT1 switch and telomere capping after replication.
DNA-PKcs-interacting protein KIP binding to TRF2 is required for the maintenance of functional telomeres.
Do schizophrenia patients age early?
Do telomeres have a higher plasticity than thought? Results from the German Chronic Kidney Disease (GCKD) study as a high-risk population.
Does ligand symmetry play a role in the stabilization of DNA G-quadruplex host-guest complexes?
Does neuroticism make you old? Prospective associations between neuroticism and leukocyte telomere length.
Does Reproductive Investment Decrease Telomere Length in Menidia menidia?
Dominant Driving Forces in Human Telomere Quadruplex Binding-Induced Structural Alterations.
Dosage of the Abcg1-U2af1 region modifies locomotor and cognitive deficits observed in the Tc1 mouse model of Down syndrome.
Double faced role of human mesenchymal stem cells and their role challenges in cancer therapy.
Double-Blind, Placebo-Controlled, Randomized Clinical Trial Demonstrates Telomerase Activator TA-65® Decreases Immunosenescent CD8+CD28- T Cells in Humans
Downregulation of high mobility group box 1 modulates telomere homeostasis and increases the radiosensitivity of human breast cancer cells.
Downregulation of Rap1 promotes 5-fluorouracil-induced apoptosis in hepatocellular carcinoma cell line HepG2.
Downregulation of telomerase maintenance-related ACD expression in patients undergoing immunosuppresive therapy following kidney transplantation.
Drosophila Rif1 is an essential gene and controls late developmental events by direct interaction with PP1-87B.
Dual disruption of DNA repair and telomere maintenance for the treatment of head and neck cancer.
Dual roles for the telomeric repeats in chromosomally integrated human herpesvirus-6.
Dubowitz syndrome is a complex comprised of multiple, genetically distinct and phenotypically overlapping disorders.
Dynamics of rye telomeres in a wheat background during early meiosis.
Dysfunction of subtelomeric methylation and telomere length in gallstone disease and gallbladder cancer patients of North Central India.
Dyskeratosis congenita associated with leukoplakia of the tongue.
Dyskeratosis Congenita Without Oral Involvement: A Rare Hereditary Disease.
Dyskeratosis congenita.
Dyskerin expression in human fetal, adult and neoplastic intrahepatic bile ducts: correlations with cholangiocarcinoma aggressiveness.
Dyslipidemia and chronic inflammation markers are correlated with telomere length shortening in Cushing's syndrome.
Dysregulated physiological stress systems and accelerated cellular aging.
Dysregulation of shelterin factors coupled with telomere shortening in Philadelphia chromosome negative myeloproliferative neoplasms.
E-type cyclins modulate telomere integrity in mammalian male meiosis.
Early and recent psychosocial stress and telomere length in older adults.
Early cellular aging: salt and the telomeres.
Early senescence in heterozygous ABCA1 mutation skin fibroblasts: a gene dosage effect beyond HDL deficiency?
Early Telomerase Inactivation Accelerates Aging Independently of Telomere Length
Early telomerase inactivation accelerates aging independently of telomere length.
Early-Life Intelligence Predicts Midlife Biological Age.
Early-Life Telomere Dynamics Differ between the Sexes and Predict Growth in the Barn Swallow (Hirundo rustica).
Early-onset Evans syndrome, immunodeficiency, and premature immunosenescence associated with tripeptidyl-peptidase II deficiency.
Effect of a qigong intervention program on telomerase activity and psychological stress in abused Chinese women: a randomized, wait-list controlled trial.
Effect of chromosome tethering on nuclear organization in yeast.
Effect of cytotoxic chemotherapy on markers of molecular age in patients with breast cancer.
Effect of delayed graft function, acute rejection and chronic allograft dysfunction on kidney allograft telomere length in patients after transplantation: a prospective cohort study.
Effect of different immunosuppressive drugs on immune cells from young and old healthy persons.
Effect of estradiol during culture of bovine oocyte-granulosa cell complexes on the mitochondrial DNA copies of oocytes and telomere length of granulosa cells.
Effect of exposure to interleukin-21 at various time points on human natural killer cell culture.
Effect of intensive exercise in early adult life on telomere length in later life in men.
Effect of leukocyte telomere length on total and regional brain volumes in a large population-based cohort.
Effect of lipopolysaccharides on adipogenic potential and premature senescence of adipocyte progenitors.
Effect of obesity on telomere length: Systematic review and meta-analysis.
Effect of sedentary activity on telomere length may not be so straightforward.
Effect of telomerase inhibition on preclinical models of malignant rhabdoid tumor.
Effect of telomere length on prognosis in men with acute coronary syndrome.
Effect of telomere length on survival in patients with idiopathic pulmonary fibrosis: an observational cohort study with independent validation.
Effect of the anatomical site on telomere length and pref-1 gene expression in bovine adipose tissues.
Effect of Tianshengyuan-1 (TSY-1) on telomerase activity and hematopoietic recovery - in vitro, ex vivo, and in vivo studies.
Effect of vegetable consumption on the association between peripheral leucocyte telomere length and hypertension: a case-control study.
Effect of weight maintenance or gain in a 10 years period over telomere length, sirtuin 1 and 6 expression and carotid intima media thickness.
Effects of aging on renal function and regenerative capacity.
Effects of baicalin against UVA-induced photoaging in skin fibroblasts.
Effects of cigarette smoking and nicotine metabolite ratio on leukocyte telomere length.
Effects of four chemotherapeutic agents, bleomycin, etoposide, cisplatin, and cyclophosphamide, on DNA damage and telomeres in a mouse spermatogonial cell line.
Effects of Lifestyle Modification on Telomerase Gene Expression in Hypertensive Patients: A Pilot Trial of Stress Reduction and Health Education Programs in African Americans.
Effects of PCB126 and PCB153 on telomerase activity and telomere length in undifferentiated and differentiated HL-60 cells.
Effects of physical activity in telomere length: Systematic review and meta-analysis.
Effects of PTEN on the longevity of cultured human umbilical vein endothelial cells: the role of antioxidants.
Effects of smoking on human telomerase reverse transcriptase expression in the skin.
Efforts of the human immune system to maintain the peripheral CD8+ T cell compartment after childhood thymectomy.
Eimeria tenella: 14-3-3 protein interacts with telomerase.
Electrophoretic karyotyping of Hypsizygus marmoreus and evaluation of variation among its basidiospores.
Elevated levels of TRF2 induce telomeric ultrafine anaphase bridges and rapid telomere deletions.
Elevated plasma magnesium and calcium may be associated with shorter telomeres in older South Australian women.
Elevated transferrin saturation, health-related quality of life and telomere length.
Elg1, a central player in genome stability.
Elucidation of the DNA end-replication problem in Saccharomyces cerevisiae.
Emerging roles of ATRX in cancer.
Emerging roles of lncRNAs in senescence.
Emerging roles of MCPH1: expedition from primary microcephaly to cancer.
Emerging therapeutic approaches based on nanotechnology for the treatment of diseases associated with telomere dysfunction.
Emotions and family interactions in childhood: Associations with leukocyte telomere length emotions, family interactions, and telomere length.
End stage renal disease patients have a skewed T cell receptor Vβ repertoire.
Endocrine abnormalities in HIV-infected women are associated with peak viral load - the Children and Women: AntiRetrovirals and Markers of Aging (CARMA) Cohort.
Endoplasmic reticulum stress activates telomerase.
Endothelial cellular senescence is inhibited by liver X receptor activation with an additional mechanism for its atheroprotection in diabetes.
Enforced telomere elongation increases the sensitivity of human tumour cells to ionizing radiation.
Engineered minichromosomes in plants.
Engineering of plant chromosomes.
Enhanced antioxidant capacity and anti-ageing biomarkers after diet micronutrient supplementation.
Enhanced microglial pro-inflammatory response to lipopolysaccharide correlates with brain infiltration and blood-brain barrier dysregulation in a mouse model of telomere shortening.
Enhanced telomere rejuvenation in pluripotent cells reprogrammed via nuclear transfer relative to induced pluripotent stem cells.
Enzyme takes us a step closer to eternal youth
Epidemiological and Mendelian Randomization Studies of Dihydrotestosterone and Estradiol and Leukocyte Telomere Length in Men.
Epigenetic clock analyses of cellular senescence and ageing.
Epigenetic inheritance of telomere length obscures identification of causative PARN locus.
Epigenetic regulation of telomere maintenance.
Epigenetic reprogramming by somatic cell nuclear transfer: questions and potential solutions.
Epigenetics and Understanding the Impact of Social Determinants of Health.
Erk signaling is indispensable for genomic stability and self-renewal of mouse embryonic stem cells.
Erratum: identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activities.
Escape from telomere-driven crisis is DNA ligase III dependent.
Essential role for the TRF2 telomere protein in adult skin homeostasis.
Estimating telomere length from whole genome sequence data.
Ethanol-Associated Cardiomyocyte Apoptosis and Left Ventricular Dilation Are Unrelated to Changes in Myocardial Telomere Length in Rats.
Evaluating the physiological reserves of older patients with cancer: the value of potential biomarkers of aging?
Evaluation and clinical significance of the stomach age model for evaluating aging of the stomach-a multicenter study in China.
Evaluation Of An Oral Telomerase Activator For Early Age-related Macular Degeneration - A Pilot Study
Evaluation of an oral telomerase activator for early age-related macular degeneration - a pilot study.
Evaluation of Initial Telomere Length and Changes after Transplantation in Adult Double-Unit Cord Blood Transplant Recipients.
Evaluation of Quantitative Fluorescence in situ Hybridization for Relative Measurement of Telomere Length in Placental Mesenchymal Core Cells.
Evaluation of the mechanism of nucleoplasmic bridge formation due to premature telomere shortening in agricultural workers exposed to mixed pesticides: indication for further studies.
Evidence that Aging and Amyloid Promote Microglial Cell Senescence
Evidence that Aging and Amyloid Promote Microglial Cell Senescence
Evolution and phenotypic selection of cancer stem cells.
Evolution of the Telomere-Associated Protein POT1a in Arabidopsis thaliana Is Characterized by Positive Selection to Reinforce Protein-Protein Interaction.
exercise
Exercise attenuates the major hallmarks of aging.
Exercise-induced mitochondrial p53 repairs mtDNA mutations in mutator mice.
Exome sequencing identifies mutant TINF2 in a family with pulmonary fibrosis.
Exome sequencing links mutations in PARN and RTEL1 with familial pulmonary fibrosis and telomere shortening.
Exome Sequencing of Uterine Leiomyosarcomas Identifies Frequent Mutations in TP53, ATRX, and MED12.
Exosome-mediated transfer of microRNAs within the tumor microenvironment and neuroblastoma resistance to chemotherapy.
Expansion of Interstitial Telomeric Sequences in Yeast.
Experimental increase in telomere length leads to faster feather regeneration.
Experimentally increased reproductive effort alters telomere length in the blue tit (Cyanistes caeruleus).
Exploiting tumor cell senescence in anticancer therapy.
Expression of a pathogenic mutation of SOD1 sensitizes aprataxin-deficient cells and mice to oxidative stress and triggers hallmarks of premature ageing.
Expression of genes involved in DNA repair and telomere maintenance in the yeast Hansenula polymorpha DL1 under heat stress.
Expression of human protection of telomere 1 correlates with telomere length and radiosensitivity in the human laryngeal cancer Hep-2 cell line.
Expression of human telomerase reverse transcriptase mediates the senescence of mesenchymal stem cells through the PI3K/AKT signaling pathway.
Expression of phosphorylated Akt and hTERT is associated with prognosis of epithelial ovarian carcinoma.
Expression of Shelterin component POT1 is associated with decreased telomere length and immunity condition in humans with severe aplastic anemia.
Expression of targeted ribozyme against telomerase RNA causes altered expression of several other genes in tumor cells.
Expression of the genetic suppressor element 24.2 (GSE24.2) decreases DNA damage and oxidative stress in X-linked dyskeratosis congenita cells.
Expression of various protection of telomeres 1 variants is associated with telomere length and radiosensitivity in colon and gastric adenocarcinoma cells in vitro.
Expression profile of shelterin components in plasma cell disorders. Clinical significance of POT1 overexpression.
Extended fertility and longevity: the genetic and epigenetic link.
Extending the model of Arabidopsis telomere length and composition across Brassicaceae.
Extensive phenotyping of individuals at risk for familial interstitial pneumonia reveals clues to the pathogenesis of interstitial lung disease.
Extensive spreading of interstitial telomeric sites on the chromosomes of Characidium (Teleostei, Characiformes).
Extra-nuclear telomerase reverse transcriptase (TERT) regulates glucose transport in skeletal muscle cells.
Extra-telomeric functions of human telomerase: cancer, mitochondria and oxidative stress.
Extracting extra-telomeric phenotypes from telomerase mouse models.
Factors related to telomere length.
Familial myelodysplastic syndrome/acute leukemia syndromes: a review and utility for translational investigations.
Familial nonmedullary thyroid cancer: screening, clinical, molecular and genetic findings.
FANCJ promotes DNA synthesis through G-quadruplex structures.
Fertility of CMS wheat is restored by two Rf loci located on a recombined acrocentric chromosome.
Fine mapping of chromosome 5p15.33 based on a targeted deep sequencing and high density genotyping identifies novel lung cancer susceptibility loci.
Fine mapping of the lesion mimic and early senescence 1 (lmes1) in rice (Oryza sativa).
First evidence for (TTAGG)n telomeric sequence and sex chromosome post-reduction in Coleorrhyncha (Insecta, Hemiptera).
First Randomized, Double-Blind, Placebo-Controlled Study to Show Telomere Lengthening in Humans
FISH (Fluorescent in Situ Hybridization)
Fission yeast Cactin restricts telomere transcription and elongation by controlling Rap1 levels.
Fission yeast telomere-binding protein Taz1 is a functional but not a structural counterpart of human TRF1 and TRF2.
Flap endonuclease 1 is a promising candidate biomarker in gastric cancer and is involved in cell proliferation and apoptosis.
Flap Endonuclease 1 Limits Telomere Fragility on the Leading Strand.
Flow cytometry and FISH to measure the average length of telomeres (flow FISH)
Flow cytometry and FISH to measure the average length of telomeres (flow FISH)
Folate deficiency induces dysfunctional long and short telomeres; both states are associated with hypomethylation and DNA damage in human WIL2-NS cells.
Food supplementation with rice bran enzymatic extract prevents vascular apoptosis and atherogenesis in ApoE-/- mice.
Forced expression of Nanog or Esrrb preserves the ESC status in the absence of nucleostemin expression.
Forging a signature of in vivo senescence.
FoxO1 signaling plays a pivotal role in the cardiac telomere biology responses to calorie restriction.
Frailty and telomere length: cross-sectional analysis in 3537 older adults from the ESTHER cohort.
Frailty is associated with the epigenetic clock but not with telomere length in a German cohort.
Frequent somatic mutations of the telomerase reverse transcriptase promoter in ovarian clear cell carcinoma but not in other major types of gynaecological malignancy.
From cellular senescence to Alzheimer's disease: The role of telomere shortening.
From the authors.
Fully automated expansion and activation of clinical-grade natural killer cells for adoptive immunotherapy.
Functional analysis of sirtuin genes in multiple Plasmodium falciparum strains.
Functional analysis of the new barley gene HvKu80 indicates that it plays a key role in double-strand DNA break repair and telomere length regulation.
Functional annotation of the Ophiostoma novo-ulmi genome: insights into the phytopathogenicity of the fungal agent of Dutch elm disease.
Functional Assessment of Pharmacological Telomerase Activators in Human T Cells
Functional characterization of the TERRA transcriptome at damaged telomeres.
Functional Effect of Pim1 Depends upon Intracellular Localization in Human Cardiac Progenitor Cells.
Functional genomics in the study of mind-body therapies.
Functional Haplotypes of the hTERT Gene, Leukocyte Telomere Length Shortening, and the Risk of Peripheral Arterial Disease
Functional role of cellular senescence in biliary injury.
Functional Significance of Nuclear α Spectrin.
Functional variants in CYP1B1, KRAS and MTHFR genes are associated with shorter telomere length in postmenopausal women.
Functions of noncoding sequences in mammalian genomes.
Fungal Ku prevents permanent cell cycle arrest by suppressing DNA damage signaling at telomeres.
G-quadruplex (G4) motifs in the maize (Zea mays L.) genome are enriched at specific locations in thousands of genes coupled to energy status, hypoxia, low sugar, and nutrient deprivation.
G-Quadruplex binding enantiomers show chiral selective interactions with human telomere.
G-quadruplex conformation and dynamics are determined by loop length and sequence.
G-quadruplex ligand-induced DNA damage response coupled with telomere dysfunction and replication stress in glioma stem cells.
G-quadruplex-mediated regulation of telomere binding protein POT1 gene expression.
G-quadruplexes in viruses: function and potential therapeutic applications.
G-quadruplexes incorporating modified constituents: a review.
G-quadruplexes significantly stimulate Pif1 helicase-catalyzed duplex DNA unwinding.
Gap junction blockade induces apoptosis in human endometrial stromal cells.
Gastrokine 1 induces senescence and apoptosis through regulating telomere length in gastric cancer.
Gathering up meiotic telomeres: a novel function of the microtubule-organizing center.
Gender and telomere length: systematic review and meta-analysis.
Gene dosage reductions of Trf1 and/or Tin2 induce telomere DNA damage and lymphoma formation in aging mice.
Gene expression profiling of replicative and induced senescence.
Gene expression, telomere and cognitive deficit analysis as a function of Chornobyl radiation dose and age: from in utero to adulthood.
Generation and characterization of Ins1-cre-driver C57BL/6N for exclusive pancreatic beta cell-specific Cre-loxP recombination.
Genetic and epigenetic background and protein expression profiles in relation to telomerase activation in medullary thyroid carcinoma.
Genetic and epigenetic trends in telomere research: a novel way in immunoepigenetics.
Genetic and intermediate phenotypic susceptibility markers of gastric cancer in Hispanic Americans: a case-control study.
Genetic and molecular identification of three human TPP1 functions in telomerase action: recruitment, activation, and homeostasis set point regulation.
Genetic architecture of natural variation of telomere length in Arabidopsis thaliana.
Genetic Burden Analyses of Phenotypes Relevant to Aging in the Berlin Aging Study II (BASE-II).
Genetic characterization of acquired aplastic anemia by targeted sequencing.
Genetic clues to predicting life span
Genetic determinants of leucocyte telomere length in children: a neglected and challenging field.
Genetic determinants of telomere length and risk of common cancers: a Mendelian randomization study.
Genetic diversity of the KIR/HLA system and susceptibility to hepatitis C virus-related diseases.
Genetic Epidemiology Research on Adult Health and Aging (GERA) Study
Genetic Inactivation of ATRX Leads to a Decrease in the Amount of Telomeric Cohesin and Level of Telomere Transcription in Human Glioma Cells.
Genetic interactions between P elements involved in piRNA-mediated repression of hybrid dysgenesis in Drosophila melanogaster.
Genetic Polymorphism, Telomere Biology and Non-Small Lung Cancer Risk.
Genetic progression of pancreatic cancer.
Genetic variant near TERC influencing the risk of gliomas with older age at diagnosis in a Chinese population.
Genetic variants associated with longer telomere length are associated with increased lung cancer risk among never-smoking women in Asia: a report from the female lung cancer consortium in Asia.
Genetic variants in telomerase reverse transcriptase (TERT) and telomerase-associated protein 1 (TEP1) and the risk of male infertility.
Genetic variants in the TEP1 gene are associated with prostate cancer risk and recurrence.
Genetic variants within telomere-associated genes, leukocyte telomere length and the risk of acute coronary syndrome in Czech women.
Genetic variations in the TERT and CLPTM1L gene region and gastrointestinal stromal tumors risk.
genetics
Genetics of aging, progeria and lamin disorders.
Genetics of familial melanoma: 20 years after CDKN2A.
Genetics: dynamic cellular aging markers associated with major depression.
Genetics: telomere length and the metabolic syndrome-a causal link?
Genome instability: Targeted telomere insertion.
Genome Integrity in Aging: Human Syndromes, Mouse Models, and Therapeutic Options.
Genome organization and DNA methylation patterns of B chromosomes in the red fox and Chinese raccoon dogs.
Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study.
Genome-wide analysis of in vivo TRF1 binding to chromatin restricts its location exclusively to telomeric repeats.
Genome-wide array-CGH analysis reveals YRF1 gene copy number variation that modulates genetic stability in distillery yeasts.
Genome-wide association study identifies variants in casein kinase II (CSNK2A2) to be associated with leukocyte telomere length in a Punjabi Sikh diabetic cohort.
Genome-wide DNA methylation changes in skeletal muscle between young and middle-aged pigs.
Genome-wide mapping of yeast histone chaperone anti-silencing function 1 reveals its role in condensin binding with chromatin.
Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma.
Genomic and protein expression analysis reveals flap endonuclease 1 (FEN1) as a key biomarker in breast and ovarian cancer.
Genomic catastrophes frequently arise in esophageal adenocarcinoma and drive tumorigenesis.
Genomic characterization of variable surface antigens reveals a telomere position effect as a prerequisite for RNA interference-mediated silencing in Paramecium tetraurelia.
Genomic determinants of somatic copy number alterations across human cancers.
Genomic distribution and possible functional roles of putative G-quadruplex motifs in two subspecies of Oryza sativa.
Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition.
Genomic instability in newborn with short telomeres.
Genomic instability: Building bridges.
Genomic landscape of human, bat, and ex vivo DNA transposon integrations.
Genomic organization and molecular characterization of porcine cytomegalovirus.
Germ-line transmitted, chromosomally integrated HHV-6 and classical Hodgkin lymphoma.
Germline mutations in shelterin complex genes are associated with familial glioma.
Germline TERT promoter mutations are rare in familial melanoma.
Geron and TA Therapeutics Announce Presentation of New Data Supporting Utility of Their Small Molecule Telomerase Activator TAT0002; TAT0002 Selected as Lead Compound for HIV/AIDS Indication
Geron Increases Stake in TA Therapeutics Joint Venture
Gerontology: Will you still need me, will you still feed me?
Giant poly(A)-rich RNP aggregates form at terminal regions of avian lampbrush chromosomes.
Ginsenoside Rg1 prevents cognitive impairment and hippocampus senescence in a rat model of D-galactose-induced aging.
Glioma a downside of long telomeres.
Global expression profile of telomerase-associated genes in HeLa cells.
Global Gene Expression Profiling in Omental Adipose Tissue of Morbidly Obese Diabetic African Americans.
Glucose substitution prolongs maintenance of energy homeostasis and lifespan of telomere dysfunctional mice.
Glutathione S-transferase gene polymorphisms in celiac disease and their correlation with genomic instability phenotype.
Glycans are a novel biomarker of chronological and biological ages.
Glyceraldehyde 3-phosphate dehydrogenase-telomere association correlates with redox status in Trypanosoma cruzi.
Gradual telomere shortening and increasing chromosomal instability among PanIN grades and normal ductal epithelia with and without cancer in the pancreas.
Growing up or growing old? Cellular aging linked with testosterone reactivity to stress in youth.
Growth properties of cardiac stem cells are a novel biomarker of patients' outcome after coronary bypass surgery.
Hairpin Telomere Resolvases.
Haploinsufficiency for BRCA1 leads to cell-type-specific genomic instability and premature senescence.
HCT116 colonospheres shows elevated expression of hTERT and β-catenin protein - a short report.
Heart failure with preserved ejection fraction: molecular pathways of the aging myocardium.
Heat shock-induced dissociation of TRF2 from telomeres does not initiate a telomere-dependent DNA damage response.
Heat stress-induced Cup9-dependent transcriptional regulation of SIR2.
Height and bone mineral density are associated with naevus count supporting the importance of growth in melanoma susceptibility.
HeLa human cervical cancer cell migration is inhibited by treatment with dibutyryl-cAMP.
Hematopoietic stem cells are acutely sensitive to Acd shelterin gene inactivation.
Hepatopulmonary syndrome is a frequent cause of dyspnea in the short telomere disorders.
Heregulin, a new interactor of the telosome/shelterin complex in human telomeres.
Heregulin, a new regulator of telomere length in human cells.
Heritability of telomere length in a study of long-lived families.
Heterozygous RTEL1 mutations are associated with familial pulmonary fibrosis.
Heterozygous splice mutation in PIK3R1 causes human immunodeficiency with lymphoproliferation due to dominant activation of PI3K.
High frequency of p16 and p14 promoter hypermethylation and marked telomere instability in salivary gland tumors.
High incidence of activating TERT promoter mutations in meningiomas undergoing malignant progression.
High Mobility Group A2 protects cancer cells against telomere dysfunction.
High nutrient levels and TORC1 activity reduce cell viability following prolonged telomere dysfunction and cell cycle arrest.
High plasma folate is negatively associated with leukocyte telomere length in Framingham Offspring cohort.
High sodium intake is associated with short leukocyte telomere length in overweight and obese adolescents.
High telomerase is a hallmark of undifferentiated spermatogonia and is required for maintenance of male germline stem cells.
High tobacco consumption is causally associated with increased all-cause mortality in a general population sample of 55,568 individuals, but not with short telomeres: a Mendelian randomization study.
High-density array comparative genomic hybridization detects novel copy number alterations in gastric adenocarcinoma.
High-risk human papillomavirus infection associated with telomere elongation in patients with esophageal squamous cell carcinoma with poor prognosis.
Highlights from the AACR International Conference.
Highly sensitive detection of telomerase using a telomere-triggered isothermal exponential amplification-based DNAzyme biosensor.
Histone H3 N-terminal acetylation sites especially K14 are important for rDNA silencing and aging.
Histone modifications rather than the novel regional centromeres of Zymoseptoria tritici distinguish core and accessory chromosomes.
Histone variant H3.3 provides the heterochromatic H3 lysine 9 tri-methylation mark at telomeres.
HIV
HnRNP-like proteins as post-transcriptional regulators.
Holokinetic centromeres and efficient telomere healing enable rapid karyotype evolution.
Homocysteine accelerates senescence of endothelial cells via DNA hypomethylation of human telomerase reverse transcriptase.
Homocysteine Levels Are not Related to Telomere Length in Cord Blood Leukocytes of Newborns.
Hormetic effect of rotenone in primary human fibroblasts.
Hormone-brain-aging relationships, broadly reactive with imidazole-containing dipeptides: targeting of telomere attrition as an aging biomarker and dynamic telomerase activity flirting.
How does the body know how old it is? Introducing the epigenetic clock hypothesis.
How homologous recombination maintains telomere integrity.
How old do you feel? The role of age discrimination and biological aging in subjective age.
Hoyeraal-Hreidarsson syndrome caused by a germline mutation in the TEL patch of the telomere protein TPP1.
Hoyeraal-Hreidarsson Syndrome due to PARN Mutations: Fourteen Years of Follow-Up.
Hoyeraal-Hreidarsson syndrome with a DKC1 mutation identified by whole-exome sequencing.
Hoyeraal-Hreidarsson Syndrome: An Extremely Rare Dyskeratosis Congenita Phenotype.
Hrq1, a homolog of the human RecQ4 helicase, acts catalytically and structurally to promote genome integrity.
Hsa-miR-520d converts fibroblasts into CD105+ populations.
Hsp90 picks PIKKs via R2TP and Tel2.
HSV-1 remodels host telomeres to facilitate viral replication.
hTERT genetic variation in depression.
hTERT, BICD1 and chromosome 18 polymorphisms associated with telomere length affect kidney allograft function after transplantation.
Human CalDAG-GEFI gene (RASGRP2) mutation affects platelet function and causes severe bleeding.
Human cells lacking coilin and Cajal bodies are proficient in telomerase assembly, trafficking and telomere maintenance.
Human CST abundance determines recovery from diverse forms of DNA damage and replication stress.
Human dyskerin: beyond telomeres.
Human endometrial epithelial telomerase is important for epithelial proliferation and glandular formation with potential implications in endometriosis.
Human Genomics. Sleeping dogs of the genome.
Human leukocyte telomere length is associated with DNA methylation levels in multiple subtelomeric and imprinted loci.
Human longevity and variation in DNA damage response and repair: study of the contribution of sub-processes using competitive gene-set analysis.
Human Rap1 modulates TRF2 attraction to telomeric DNA.
Human RECQL1 participates in telomere maintenance.
Human regulator of telomere elongation helicase 1 (RTEL1) is required for the nuclear and cytoplasmic trafficking of pre-U2 RNA.
Human ribosomes from cells with reduced dyskerin levels are intrinsically altered in translation.
Human telomerase reverse transcriptase (hTERT) extends the lifespan of canine chondrocytes in vitro without inducing neoplastic transformation
Human telomerase reverse transcriptase (hTERT) extends the lifespan of canine chondrocytes in vitro without inducing neoplastic transformation
Human telomerase reverse transcriptase (hTERT) promotes cancer invasion by modulating cathepsin D via early growth response (EGR)-1.
Human telomerase reverse transcriptase binds to a pre-organized hTR in vivo exposing its template.
Human telomerase specialization for repeat synthesis by unique handling of primer-template duplex.
Human telomerase: biogenesis, trafficking, recruitment, and activation.
Human telomere biology: A contributory and interactive factor in aging, disease risks, and protection.
Human Telomere G-Quadruplexes with Five Repeats Accommodate 8-Oxo-7,8-dihydroguanine by Looping out the DNA Damage.
Human telomeres and telomere biology disorders.
Human telomeres that carry an integrated copy of human herpesvirus 6 are often short and unstable, facilitating release of the viral genome from the chromosome.
Human telomeric RNA G-quadruplex response to point mutation in the G-quartets.
Hyper-Acetylation of Histone H3K56 Limits Break-Induced Replication by Inhibiting Extensive Repair Synthesis.
Hypercholesterolemia induces oxidant stress that accelerates the ageing of hematopoietic stem cells.
Hypothesis testing of meiotic recombination rates from population genetic data.
Hypothesis: Paralog Formation from Progenitor Proteins and Paralog Mutagenesis Spur the Rapid Evolution of Telomere Binding Proteins.
Ideal body condition improves reproductive performance and influences genetic health in female mink.
Identification of a robust molecular marker for the detection of the stem rust resistance gene Sr45 in common wheat.
Identification of a Selective G1-Phase Benzimidazolone Inhibitor by a Senescence-Targeted Virtual Screen Using Artificial Neural Networks.
Identification of a telomeric DNA-binding protein in Eimeria tenella.
Identification of degenerate nuclei and development of a SCAR marker for Flammulina velutipes.
Identification of genes with altered expression in male and female Schlager hypertensive mice.
Identification of human TERT elements necessary for telomerase recruitment to telomeres.
Identification of non-coding RNAs associated with telomeres using a combination of enChIP and RNA sequencing.
Identification of novel interactors of human telomeric G-quadruplex DNA.
Identification of novel noncoding transcripts in telomerase-negative yeast using RNA-seq.
Identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activities.
Identification of novel therapeutic targets in the secretome of ionizing radiation‑induced senescent tumor cells.
Identification of proteins that form specific complexes with the highly conserved protein Translin in Schizosaccharomyces pombe.
Identification of telomere dysfunction in Friedreich ataxia.
Identification of TERRA locus unveils a telomere protection role through association to nearly all chromosomes.
Identification of TTAGGG-binding proteins in Neurospora crassa, a fungus with vertebrate-like telomere repeats.
Idiopathic aplastic anemia: diagnosis and classification.
If the cap fits, wear it: an overview of telomeric structures over evolution.
Imaging genomic elements in living cells using CRISPR/Cas9.
Immediate and delayed effects of growth conditions on ageing parameters in nestling zebra finches.
Immortalization of normal human mammary epithelial cells in two steps by direct targeting of senescence barriers does not require gross genomic alterations.
immune system
Immunological features of T cells induced by human telomerase reverse transcriptase-derived peptides in patients with hepatocellular carcinoma.
Immunotherapy of tumors with human telomerase reverse transcriptase immortalized human umbilical vein endothelial cells.
Impact of chemotherapy on telomere length in sporadic and familial breast cancer patients.
Impact of gender and menopausal status on relationships between biological aging, as indexed by telomere length, and aortic stiffness.
Impact of intrauterine tobacco exposure on fetal telomere length.
Impact of telomere length on survival in classic and variant hairy cell leukemia.
Impaired proliferative potential of bone marrow mesenchymal stromal cells in patients with myelodysplastic syndromes is associated with abnormal WNT signaling pathway.
Impaired telomerase activity hinders proliferation and in vitro transformation of Penaeus monodon lymphoid cells.
Impaired Telomere Maintenance and Decreased Canonical WNT Signaling but Normal Ribosome Biogenesis in Induced Pluripotent Stem Cells from X-Linked Dyskeratosis Congenita Patients.
Improving qPCR telomere length assays: Controlling for well position effects increases statistical power.
In colon cancer, normal colon tissue and blood cells have altered telomere lengths.
In every end there is a beginning--telomeres in male reproduction.
In silico characterization and analysis of RTBP1 and NgTRF1 protein through MD simulation and molecular docking - A comparative study.
In Silico Characterization and Analysis of RTBP1 and NgTRF1 Protein Through MD Simulation and Molecular Docking: A Comparative Study.
In situ localization of (GATA)n and (TTAGGG)n repeated DNAs and W sex chromosome differentiation in Parodontidae (Actinopterygii: Characiformes).
In situ normoxia enhances survival and proliferation rate of human adipose tissue-derived stromal cells without increasing the risk of tumourigenesis.
In the end it's a replication problem: What measuring telomere length can tell us about idiopathic pulmonary fibrosis.
In the end, what's the problem?
In vitro lifespan and senescence mechanisms of human nucleus pulposus chondrocytes.
In vivo analysis of a fluorescent SUMO fusion in transgenic Drosophila.
In vivo role of checkpoint kinase 2 in signaling telomere dysfunction.
Inactive C-terminal telomerase reverse transcriptase insertion splicing variants are dominant-negative inhibitors of telomerase.
Inconsistent inheritance of telomere length (TL): is offspring TL more strongly correlated with maternal or paternal TL?
Increase in rates of short telomeres predicts longevity in mammals
Increased attrition of leukocyte telomere length in young adults is associated with poorer cognitive function in midlife.
Increased body mass index, elevated C-reactive protein, and short telomere length.
Increased DNA damage and repair deficiency in granulosa cells are associated with ovarian aging in rhesus monkey.
Increased expression of stathmin and elongation factor 1α in precancerous nodules with telomere dysfunction in hepatitis B viral cirrhotic patients.
Increased expression of telomere-regulating genes in endurance athletes with long leukocyte telomeres.
Increased in vitro glial fibrillary acidic protein expression, telomerase activity, and telomere length after productive human immunodeficiency virus-1 infection in murine astrocytes.
Increased paired box transcription factor 8 has a survival function in glioma.
Increased sugar uptake promotes oncogenesis via EPAC/RAP1 and O-GlcNAc pathways.
Increased telomerase activity and comprehensive lifestyle changes: a pilot study
Increased telomerase activity and comprehensive lifestyle changes: a pilot study
Independent replication of a melanoma subtype gene signature and evaluation of its prognostic value and biological correlates in a population cohort.
Individual telomere length decay in patients with spondyloarthritis.
Indolo[3,2-c]quinoline G-quadruplex stabilizers: a structural analysis of binding to the human telomeric G-quadruplex.
Induced pluripotent stem cells as a model for telomeric abnormalities in ICF type I syndrome.
Induction of telomere dysfunction mediated by the telomerase substrate precursor 6-thio-2'-deoxyguanosine.
Infant-caregiver experiences alter telomere length in the brain.
Inflamm-ageing and Senescence in Gout: The Tale of an Old King's Disease.
Inflammation, But Not Telomere Length, Predicts Successful Ageing at Extreme Old Age: A Longitudinal Study of Semi-supercentenarians.
Inflammation, telomere length, and grip strength: a 10-year longitudinal study.
Inflammatory biomarkers and telomere length in women with polycystic ovary syndrome.
Influence of calorie reduction on DNA repair capacity of human peripheral blood mononuclear cells.
Influence of endothelial dysfunction on telomere length in subjects with metabolic syndrome: LIPGENE study.
Influence of mindfulness-based stress reduction (MBSR) on telomerase activity in women with breast cancer (BC).
Influence of the delivery modus on subpopulations and replication of lymphocytes in mothers and newborns.
Influence of the hTERT rs2736100 polymorphism on telomere length in gastric cancer.
Inherited bone marrow failure associated with germline mutation of ACD, the gene encoding telomere protein TPP1.
Inherited chromosomally integrated human herpesvirus 6 as a predisposing risk factor for the development of angina pectoris.
Inherited predisposition to acute myeloid leukemia.
Inhibiting Tankyrases sensitizes KRAS-mutant cancer cells to MEK inhibitors via FGFR2 feedback signaling.
Inhibition of human telomerase reverse transcriptase in vivo and in vitro for retroviral vector-based antisense oligonucleotide therapy in ovarian cancer.
Inhibition of RAP1 enhances corneal recovery following alkali injury.
Inhibition of telomerase activity by dominant-negative hTERT retards the growth of breast cancer cells.
Inhibition of telomerase activity by NME2: impact on metastasis suppression?
Inhibition of telomere recombination by inactivation of KEOPS subunit Cgi121 promotes cell longevity.
Inhibition of zygotic DNA repair: transcriptome analysis of the offspring in trout (Oncorhynchus mykiss).
Initiation of recombination suppression and PAR formation during the early stages of neo-sex chromosome differentiation in the Okinawa spiny rat, Tokudaia muenninki.
Inositol phosphate pathway controls transcription of telomeric expression sites in trypanosomes.
Inositol pyrophosphates mediate the DNA-PK/ATM-p53 cell death pathway by regulating CK2 phosphorylation of Tti1/Tel2.
Inositol pyrophosphates modulate cell cycle independently of alteration in telomere length.
Insomnia and Telomere Length in Older Adults.
Integrated genomic characterization of adrenocortical carcinoma.
Integrated pathway and epistasis analysis reveals interactive effect of genetic variants at TERF1 and AFAP1L2 loci on melanoma risk.
Integration of genomic information in the clinical management of HCC.
Integrative analysis of the microRNA-mRNA response to radiochemotherapy in primary head and neck squamous cell carcinoma cells.
Interaction between Bovine leukemia virus (BLV) infection and age on telomerase misregulation.
Interaction of G-quadruplexes in the full-length 3' human telomeric overhang.
Interaction of human telomeric G-quadruplex DNA with thymoquinone: a possible mechanism for thymoquinone anticancer effect.
Interactions of ruthenium complexes containing indoloquinoline moiety with human telomeric G-quadruplex DNA.
Interchromosomal homology searches drive directional ALT telomere movement and synapsis.
Intermittent high glucose implements stress-induced senescence in human vascular endothelial cells: role of superoxide production by NADPH oxidase.
Internalizing disorders and leukocyte telomere erosion: a prospective study of depression, generalized anxiety disorder and post-traumatic stress disorder.
Interorganelle interactions and inheritance patterns of nuclei and vacuoles in budding yeast meiosis.
Interplay between nonsense-mediated mRNA decay and DNA damage response pathways reveals that Stn1 and Ten1 are the key CST telomere-cap components.
Interstitial Lung Disease in Werner Syndrome: A Case Report of a 55-Year-Old Male Patient.
Intramolecular telomeric G-quadruplexes dramatically inhibit DNA synthesis by replicative and translesion polymerases, revealing their potential to lead to genetic change.
Intratumoral diversity of telomere length in individual neuroblastoma tumors.
Introgressive hybridization as a promoter of genome reshuffling in natural homoploid fish hybrids (Cyprinidae, Leuciscinae).
Inula Viscosa Extracts Induces Telomere Shortening and Apoptosis in Cancer Cells and Overcome Drug Resistance.
Investigating the functional implications of reinforcing feedback loops in transcriptional regulatory networks.
Involvement of interstitial telomeric sequences in two new cases of mosaicism for autosomal structural rearrangements.
Involvement of SRSF11 in cell cycle-specific recruitment of telomerase to telomeres at nuclear speckles.
Involvement of telomerase reverse transcriptase in heterochromatin maintenance.
Irreparable telomeric DNA damage and persistent DDR signalling as a shared causative mechanism of cellular senescence and ageing.
Is bipolar disorder associated with accelerating aging? A meta-analysis of telomere length studies.
Is childhood stress associated with shorter telomeres?
Is chronic asthma associated with shorter leukocyte telomere length at midlife?
Is Post-Traumatic Stress Disorder Associated with Premature Senescence? A Review of the Literature.
Is Senescence Reversible?
Is Southern blotting necessary to measure telomere length reproducibly? Authors' Response to: Commentary: The reliability of telomere length measurements.
Is telomeropathy the explanation for combined pulmonary fibrosis and emphysema syndrome?: report of a family with TERT mutation.
Isolation of chromatin from dysfunctional telomeres reveals an important role for Ring1b in NHEJ-mediated chromosome fusions.
Janus-faces of NME-oncoprotein interactions.
Karyological characterization of the endemic Iberian rock lizard, Iberolacerta monticola (Squamata, Lacertidae): insights into sex chromosome evolution.
Karyotype analysis and chromosomal distribution of repetitive DNA sequences of cucumis metuliferus using fluorescence in situ hybridization.
Karyotype rearrangements and telomere analysis in Myzuspersicae (Hemiptera, Aphididae) strains collected on Lavandula sp. plants.
Karyotypic diversity in seven Amazonian anurans in the genus Hypsiboas (family Hylidae).
Keeping 53BP1 out of focus in mitosis.
Keeping It in the Family: ATRX Loss Promotes Persistent Sister Telomere Cohesion in ALT Cancer Cells.
Keeping those telomeres short! an innovative intratumoral long-term drug delivery system.
Killer immunoglobulin-like receptor gene repertoire influences viral load of primary human cytomegalovirus infection in renal transplant patients.
Kinetochore assembly and heterochromatin formation occur autonomously in Schizosaccharomyces pombe.
Klotho Prevents NFκB Translocation and Protects Endothelial Cell From Senescence Induced by Uremia.
KML001, a telomere-targeting drug, sensitizes glioblastoma cells to temozolomide chemotherapy and radiotherapy through DNA damage and apoptosis.
Knockdown of telomeric repeat binding factor 2 enhances tumor radiosensitivity regardless of telomerase status.
L’OREAL-UNESCO Awards Honor UCSF Biologist for Pioneering Research in DNA Synthesis
Lack of activation of telomere maintenance mechanisms in human adipose stromal cells derived from fatty portion of lipoaspirates.
Lack of causal relationship between leukocyte telomere length and coronary heart disease.
Lack of major genome instability in tumors of p53 null rats.
Late-born intermittently fasted juvenile garden dormice use torpor to grow and fatten prior to hibernation: consequences for ageing processes.
Leiomyosarcoma with alternative lengthening of telomeres is associated with aggressive histologic features, loss of ATRX expression, and poor clinical outcome.
Leisure-Time Screen-Based Sedentary Behavior and Leukocyte Telomere Length: Implications for a New Leisure-Time Screen-Based Sedentary Behavior Mechanism.
Length-dependent processing of telomeres in the absence of telomerase.
Leucocyte Telomere Length and Risk of Cardiovascular Disease in a Cohort of 1,397 Danish Men and Women.
Leucocyte telomere length and risk of cardiovascular disease: systematic review and meta-analysis.
Leucocyte telomere length and risk of type 2 diabetes mellitus: new prospective cohort study and literature-based meta-analysis.
Leucocyte telomere length as marker for cardiovascular ageing.
Leucocyte telomere length in patients with sickle cell disease.
Leucocyte telomere shortening in relation to newly diagnosed type 2 diabetic patients with depression.
Leukocyte telomere length and age at menopause.
Leukocyte Telomere Length and Cancer Risk: A Dynamic Problem.
Leukocyte Telomere Length and Cardiovascular Disease in the Cardiovascular Health Study
Leukocyte telomere length and coronary artery calcium.
Leukocyte telomere length and diabetes status, duration, and control: the 1999-2002 National Health and Nutrition Examination Survey.
Leukocyte telomere length and hemostatic factors in a South African cohort: the SABPA Study.
Leukocyte telomere length and hippocampus volume: a meta-analysis.
Leukocyte telomere length and its association with mammographic density and proliferative diagnosis among women undergoing diagnostic image-guided breast biopsy.
Leukocyte telomere length and late-life depression.
Leukocyte telomere length and left ventricular function after acute ST-elevation myocardial infarction: data from the glycometabolic intervention as adjunct to primary coronary intervention in ST elevation myocardial infarction (GIPS-III) trial.
Leukocyte telomere length and mortality in the National Health and Nutrition Examination Survey, 1999-2002.
Leukocyte telomere length and prevalence of age-related diseases in semisupercentenarians, centenarians and centenarians' offspring.
Leukocyte Telomere Length and Risks of Incident Coronary Heart Disease and Mortality in a Racially Diverse Population of Postmenopausal Women.
Leukocyte telomere length associates with prospective mortality independent of immune-related parameters and known genetic markers.
Leukocyte telomere length dynamics in women and men: menopause vs age effects.
Leukocyte Telomere Length in Alzheimer's Disease Patients with a Different Rate of Progression.
Leukocyte telomere length in mastocytosis: correlations with depression and perceived stress.
Leukocyte telomere length in patients with schizophrenia: A meta-analysis.
Leukocyte telomere length in relation to pancreatic cancer risk: a prospective study.
Leukocyte Telomere Length in Young Adults Born Preterm: Support for Accelerated Biological Ageing.
Leukocyte telomere length is associated with advanced age-related macular degeneration in the Han Chinese population.
Leukocyte Telomere Length is Associated With Serum Vitamin B12 and Homocysteine Levels in Older Adults With the Presence of Systemic Inflammation.
Leukocyte telomere length is not associated with mortality in older men.
Leukocyte telomere length is preserved with aging in endurance exercise-trained adults and related to maximal aerobic capacity.
Leukocyte telomere length is preserved with aging in endurance exercise-trained adults and related to maximal aerobic capacity.
Leukocyte telomere length is related to appendicular lean mass: cross-sectional data from the Berlin Aging Study II (BASE-II).
Leukocyte telomere length variation due to DNA extraction method.
Leukocyte telomere length-related rs621559 and rs398652 genetic variants influence risk of HBV-related hepatocellular carcinoma.
Leukocyte telomere length: a novel biomarker to predict the prognosis of glioma patients.
Leukocyte telomere shortening in grown-up patients with congenital heart disease.
Leukocytes of Exceptionally Old Persons Display Ultra-short Telomeres
Leukoencephalopathy with calcifications and cysts: a purely neurological disorder distinct from coats plus.
Leukoencephalopathy, cerebral calcifications and cysts: a family study.
Level of macroautophagy drives senescent keratinocytes into cell death or neoplastic evasion.
Li-Fraumeni syndrome: cancer risk assessment and clinical management.
Life-Long Implications of Developmental Exposure to Environmental Stressors: New Perspectives.
Lifelong leukocyte telomere dynamics and survival in a free-living mammal.
lifestyle
Lifestyle change may reduce aging, disease
LINE-1 induces hTERT and ensures telomere maintenance in tumour cell lines.
Linking ATM Promoter Methylation to Cell Cycle Protein Expression in Brain Tumor Patients: Cellular Molecular Triangle Correlation in ATM Territory.
Links between nucleolar activity, rDNA stability, aneuploidy and chronological aging in the yeast Saccharomyces cerevisiae.
Liposome-Adenoviral hTERT-siRNA Knockdown in Fibroblasts from Keloids Reduce Telomere Length and Fibroblast Growth.
Liver failure due to hepatic angiosarcoma in an adolescent with dyskeratosis congenita.
LMP1 mediates multinuclearity through downregulation of shelterin proteins and formation of telomeric aggregates.
Local and regional chromatin silencing in Candida glabrata: consequences for adhesion and the response to stress.
Locational diversity of alpha satellite DNA and intergeneric hybridization aspects in the Nomascus and Hylobates genera of small apes.
Locus-specific control of DNA resection and suppression of subtelomeric VSG recombination by HAT3 in the African trypanosome.
Log (TG)/HDL-C ratio as a predictor of decreased islet beta cell function in patients with type 2 diabetes: 6-year cohort study.
Long G2 accumulates recombination intermediates and disturbs chromosome segregation at dysfunction telomere in Schizosaccharomyces pombe.
Long leukocyte telomere length at diagnosis is a risk factor for dementia progression in idiopathic parkinsonism.
Long noncoding RNAs in aging and age-related diseases.
Long noncoding RNAs(lncRNAs) and the molecular hallmarks of aging.
Long tails, short telomeres: Dyskeratosis congenita.
Long telomere length and a TERT-CLPTM1 locus polymorphism association with melanoma risk.
Long telomeres are associated with clonality in wild populations of the fissiparous starfish Coscinasterias tenuispina.
Long-term in vitro expansion of human adipose-derived stem cells showed low risk of tumourigenicity.
Long-term quiescent fibroblast cells transit into senescence.
Longer genotypically-estimated leukocyte telomere length is associated with increased adult glioma risk.
Longer telomere length in COPD patients with α1-antitrypsin deficiency independent of lung function.
Longer telomeres are associated with cancer risk in MMR-proficient hereditary non-polyposis colorectal cancer.
Longer telomeres in chronic, moderate, unconjugated hyperbilirubinaemia: insights from a human study on Gilbert's Syndrome.
longevity
Longitudinal association of telomere length and obesity indices in an intervention study with a Mediterranean diet: the PREDIMED-NAVARRA trial.
Longitudinal Associations Between Metabolic Syndrome Components and Telomere Shortening.
Longitudinal changes in leukocyte telomere length and mortality in humans.
Longitudinal changes of telomere length and epigenetic age related to traumatic stress and post-traumatic stress disorder.
Longitudinal Telomere Erosion in Lymphocyte Subsets of Patients with Atherosclerotic Peripheral Arterial Disease (PAD).
Longitudinal telomere length shortening and cognitive and physical decline in later life: The Lothian Birth Cohorts 1936 and 1921.
Loop flexibility in human telomeric quadruplex small-molecule complexes.
Loss of ATRX Suppresses Resolution of Telomere Cohesion to Control Recombination in ALT Cancer Cells.
Loss of DAXX and ATRX are associated with chromosome instability and reduced survival of patients with pancreatic neuroendocrine tumors.
Loss of lager specific genes and subtelomeric regions define two different Saccharomyces cerevisiae lineages for Saccharomyces pastorianus Group I and II strains.
Loss of lamin B1 results in prolongation of S phase and decondensation of chromosome territories.
Loss of the Set2 histone methyltransferase increases cellular lifespan in yeast cells.
Low Birth Weight in MZ Twins Discordant for Birth Weight is Associated with Shorter Telomere Length and lower IQ, but not Anxiety/Depression in Later Life.
Low vitamin D levels predict clinical features of schizophrenia.
Lower Extremity Muscular Strength and Leukocyte Telomere Length: Implications of Muscular Strength in Attenuating Age-Related Chronic Disease.
Lower placental telomere length may be attributed to maternal residential traffic exposure; a twin study.
Lung transplantation in telomerase mutation carriers with pulmonary fibrosis.
Lymphocyte telomere length is long in BRCA1 and BRCA2 mutation carriers regardless of cancer-affected status.
MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection.
Mainstream News
Maintenance of heterochromatin boundary and nucleosome composition at promoters by the Asf1 histone chaperone and SWR1-C chromatin remodeler in Saccharomyces cerevisiae.
Major depressive disorder and accelerated cellular aging: results from a large psychiatric cohort study.
Making Cells Live Forever in Quest for Cures
MALDI-Mass Spectrometric Imaging Revealing Hypoxia-Driven Lipids and Proteins in a Breast Tumor Model.
Mammalian E-type cyclins control chromosome pairing, telomere stability and CDK2 localization in male meiosis.
Mammalian polymerase θ promotes alternative NHEJ and suppresses recombination.
Mapping centromeres of microchromosomes in the zebra finch (Taeniopygia guttata) using half-tetrad analysis.
Mapping the conformation of a client protein through the Hsp70 functional cycle.
Markers of cellular senescence. Telomere shortening as a marker of cellular senescence.
Maternal and genetic factors determine early life telomere length.
Maternal effects underlie ageing costs of growth in the zebra finch (Taeniopygia guttata).
Maternal estriol concentrations in early gestation predict infant telomere length.
Maternal Folate Concentration in Early Pregnancy and Newborn Telomere Length.
Maternal Smoke Exposure Impairs the Long-Term Fertility of Female Offspring in a Murine Model.
Maternal Telomere Length and Risk of Down Syndrome: Epidemiological Impact of Smokeless Chewing Tobacco and Oral Contraceptive on Segregation of Chromosome 21.
Maternal telomere length inheritance in the king penguin.
Mathematical model of alternative mechanism of telomere length maintenance.
Mating-type switching by chromosomal inversion in methylotrophic yeasts suggests an origin for the three-locus Saccharomyces cerevisiae system.
Measurement of telomere length: a new assay using QuantiGene chemistry on a Luminex platform.
Measuring telomere length and telomere dynamics in evolutionary biology and ecology.
Mechanism and regulation of rapid telomere prophase movements in mouse meiotic chromosomes.
Mechanism of race-dependent platelet activation through the protease-activated receptor-4 and Gq signaling axis.
Mechanisms and clinical applications of chromosomal instability in lymphoid malignancy.
Mechanisms of development of multimorbidity in the elderly.
Mediterranean diet and leukocyte telomere length in a multi-ethnic elderly population.
Mediterranean diet and telomere length in high cardiovascular risk subjects from the PREDIMED-NAVARRA study.
Mediterranean diet and telomere length in Nurses' Health Study: population based cohort study.
Mediterranean diet and telomere length.
Meiosis-specific cohesin mediates homolog recognition in mouse spermatocytes.
Meiotic chromosome movements in plants, a puppet show?
Meiotic cohesin STAG3 is required for chromosome axis formation and sister chromatid cohesion.
Melanoma of non-sun exposed skin in a man with previous prostate cancer: recognition of a recently confirmed association.
Mendelian randomization studies in coronary artery disease.
Mesenchymal stem cells of different origin: Comparative evaluation of proliferative capacity, telomere length and pluripotency marker expression.
Mesenchymal stem cells-based therapy as a potential treatment in neurodegenerative disorders: is the escape from senescence an answer?
Mesenchymal stem cells, cancer challenges and new directions.
Meta-analysis of Telomere Length in Alzheimer's Disease.
Metabolic dysfunction consistent with premature aging results from deletion of Pim kinases.
Metabolic profiles of biological aging in American Indians: the Strong Heart Family Study.
Metabolic Syndrome
Metabolism of DNA secondary structures at the eukaryotic replication fork.
Metabolomics profiling reveals novel markers for leukocyte telomere length.
Metformin improves putative longevity effectors in peripheral mononuclear cells from subjects with prediabetes. A randomized controlled trial.
Method for monitoring deletions in the aflatoxin biosynthesis gene cluster of Aspergillus flavus with multiplex PCR.
Methylated TRF2 associates with the nuclear matrix and serves as a potential biomarker for cellular senescence.
Mice with Pulmonary Fibrosis Driven by Telomere Dysfunction.
Microarray analysis of 50 patients reveals the critical chromosomal regions responsible for 1p36 deletion syndrome-related complications.
Microenvironmental regulation of telomerase isoforms in human embryonic stem cells.
Microparticles Impair Hypotensive Cerebrovasodilation and Cause Hippocampal Neuronal Cell Injury after Traumatic Brain Injury.
MicroRNA-34 Family and Its Role in Cardiovascular Disease.
MicroRNA-dependent regulation of telomere maintenance mechanisms: a field as much unexplored as potentially promising.
MicroRNAs as Mediators of the Ageing Process.
Migration and stress during reproduction govern telomere dynamics in a seabird.
Mindfulness-based cancer recovery and supportive-expressive therapy maintain telomere length relative to controls in distressed breast cancer survivors.
Mindfulness: the untapped innate catalyst for healing, happiness and health.
Minding the body: psychotherapy and cancer survival.
Minichromosomes and artificial chromosomes in Arabidopsis.
Minishelterins separate telomere length regulation and end protection in fission yeast.
miR-155 drives telomere fragility in human breast cancer by targeting TRF1.
Mir-23a induces telomere dysfunction and cellular senescence by inhibiting TRF2 expression.
miR-34 is associated with poor prognosis of patients with gallbladder cancer through regulating telomere length in tumor stem cells.
miR-34a induces cellular senescence via modulation of telomerase activity in human hepatocellular carcinoma by targeting FoxM1/c-Myc pathway.
miR-512-5p suppresses tumor growth by targeting hTERT in telomerase positive head and neck squamous cell carcinoma in vitro and in vivo.
Mitochondrial Aging: Focus on Mitochondrial DNA Damage in Atherosclerosis - A Mini-Review.
Mitochondrial genome regulates mitotic fidelity by maintaining centrosomal homeostasis.
Mitochondrial metabolic failure in telomere attrition-provoked aging of bone marrow mesenchymal stem cells.
Mitochondrial retrograde signaling inhibits the survival during prolong S/G2 arrest in Saccharomyces cerevisiae.
Mitosis inhibits DNA double-strand break repair to guard against telomere fusions.
Mitosis, double strand break repair, and telomeres: a view from the end: how telomeres and the DNA damage response cooperate during mitosis to maintain genome stability.
Mitotic stability of small supernumerary marker chromosomes depends on their shape and telomeres - a long term in vitro study.
Mixed Integer Linear Programming based machine learning approach identifies regulators of telomerase in yeast.
Mode-specific physical activity and leukocyte telomere length among U.S. adults: Implications of running on cellular aging.
Modelling the regulation of telomere length: the effects of telomerase and G-quadruplex stabilising drugs.
Models to explore genetics of human aging.
Moderate and intense exercise lifestyles attenuate the effects of aging on telomere length and the survival and composition of T cell subpopulations.
Modern genome editing meets telomeres: the many functions of TPP1.
Molecular and biological hallmarks of ageing.
Molecular and physical characterization of the complex pericentromeric heterochromatin of the vole species Microtus thomasi.
Molecular aspects of renal senescence.
Molecular basis of telomere dysfunction in human genetic diseases.
Molecular biomarkers for chronological age in animal ecology.
Molecular cytogenetic analyses of Epinephelus bruneus and Epinephelus moara (Perciformes, Epinephelidae).
Molecular Cytogenetic Analysis of Deschampsia antarctica Desv. (Poaceae), Maritime Antarctic.
Molecular cytogenetic characterization of the dioecious Cannabis sativa with an XY chromosome sex determination system.
Molecular dynamics and principal components of potassium binding with human telomeric intra-molecular G-quadruplex.
Molecular inhibition of telomerase recruitment using designer peptides: an in silico approach.
Molecular mechanism of endothelial and vascular aging: implications for cardiovascular disease.
Molecular mechanisms of activity and derepression of alternative lengthening of telomeres.
Molecular mechanisms of ageing and related diseases.
Molecular mechanisms of homologous chromosome pairing and segregation in plants.
Molecular profiling of liver tumors: classification and clinical translation for decision making.
Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma.
Molecular recognition in complexes of TRF proteins with telomeric DNA.
Molecular Recognition of Parallel DNA Quadruplex d(TTAGGGT)4 by Mitoxantrone: Binding with 1:2 Stoichiometry Leading to Thermal Stabilization and Telomerase Inhibition.
Molecular responses in the telomere-mitochondrial axis of ageing in the elderly: a candidate gene approach.
Molecular signatures of major depression.
Molecular targeting of TRF2 suppresses the growth and tumorigenesis of glioblastoma stem cells.
MoMyb1 is required for asexual development and tissue-specific infection in the rice blast fungus Magnaporthe oryzae.
Monitoring the DNA Damage Response at Dysfunctional Telomeres.
Mono-allelic VSG expression by RNA polymerase I in Trypanosoma brucei: expression site control from both ends?
Monosomy 1p36 - a multifaceted and still enigmatic syndrome: four clinically diverse cases with shared white matter abnormalities.
Morphological and Functional Characteristic of Senescent Cancer Cells.
Mother-offspring and nest-mate resemblance but no heritability in early-life telomere length in white-throated dippers.
Mouse BRWD1 is critical for spermatid postmeiotic transcription and female meiotic chromosome stability.
Mouse CCDC79 (TERB1) is a meiosis-specific telomere associated protein.
Mouse models of telomere dysfunction phenocopy skeletal changes found in human age-related osteoporosis.
Movement-Based Behaviors and Leukocyte Telomere Length among US Adults.
Mre11 and Blm-Dependent Formation of ALT-Like Telomeres in Ku-Deficient Ustilago maydis.
Mre11-Sae2 and RPA Collaborate to Prevent Palindromic Gene Amplification.
mRNA deadenylation and telomere disease.
MST-312 Alters Telomere Dynamics, Gene Expression Profiles and Growth in Human Breast Cancer Cells.
Multifunctional cytomegalovirus (CMV)-specific CD8(+) T cells are not restricted by telomere-related senescence in young or old adults.
Multifunctional role of ATM/Tel1 kinase in genome stability: from the DNA damage response to telomere maintenance.
Multiple facets of TPP1 in telomere maintenance.
Multiple measures of adiposity are associated with mean leukocyte telomere length in the northern Finland birth cohort 1966.
Multiple Mechanisms Contribute to the Cell Growth Defects Imparted by Human Telomerase Insertion in Fingers Domain Mutations Associated with Premature Aging Diseases.
Multiple Pathways Control the Reactivation of Telomerase in HTLV-I-Associated Leukemia.
Multiplex ligation-dependent probe amplification to subtelomeric rearrangements in idiopathic intellectual disability in Colombia.
MUS81-EME2 promotes replication fork restart.
Mutational analysis of telomere complex genes in Indian population with acquired aplastic anemia.
Mutational landscape of yeast mutator strains.
Mutations in POT1 predispose to familial cutaneous malignant melanoma.
Mutations in TERT promoter and FGFR3 and telomere length in bladder cancer.
Mutations of the RTEL1 Helicase in a Hoyeraal-Hreidarsson Syndrome Patient Highlight the Importance of the ARCH Domain.
Myocardial ischemia and reperfusion leads to transient CD8 immune deficiency and accelerated immunosenescence in CMV-seropositive patients.
NAC selectively inhibit cancer telomerase activity: A higher redox homeostasis threshold exists in cancer cells.
Naïve T-cells in myelodysplastic syndrome display intrinsic human telomerase reverse transcriptase (hTERT) deficiency
Nanoparticle-mediated decrease of lamin B1 pools promotes a TRF protein-based adaptive response in cultured cells.
Nanopore detection of 8-oxoguanine in the human telomere repeat sequence.
Neighborhood characteristics and leukocyte telomere length: the Multi-Ethnic Study of Atherosclerosis.
Neil2-null Mice Accumulate Oxidized DNA Bases in the Transcriptionally Active Sequences of the Genome and Are Susceptible to Innate Inflammation.
Nestling telomere shortening, but not telomere length, reflects developmental stress and predicts survival in wild birds.
Neurobiology
Neuroendocrine and viral correlates of premature immunosenescence.
New asthma biomarkers: shorter telomeres, longer disease?
New genetic markers for male infertility.
New insights in amyloid beta interactions with human telomerase.
New insights into nucleolar structure and function.
New Study Observes the Impact of Telomerase Activation on Metabolic and Cardiovascular Health Markers
New surprises from an old favourite: The emergence of telomerase as a key player in the regulation of cancer stemness.
New use for an old reagent: Cell cycle analysis of DNA content using flow cytometry in formamide treated cells.
Nijmegen breakage syndrome fibroblasts expressing the C-terminal truncated NBN(p70) protein undergo p38/MK2-dependent premature senescence.
No association between blood telomere length and longitudinally assessed diet or adiposity in a young adult Filipino population.
No association between mean telomere length and life stress observed in a 30 year birth cohort.
No DDRama at chromosome ends: TRF2 takes centre stage.
No difference in the rate of change in telomere length or telomerase activity in HIV-infected patients after three years of darunavir/ritonavir with and without nucleoside analogues in the MONET trial.
No impact of lentiviral transduction on hematopoietic stem/progenitor cell telomere length or gene expression in the rhesus macaque model.
No Interstitial Telomeres on Autosomes but Remarkable Amplification of Telomeric Repeats on the W Sex Chromosome in the Sand Lizard (Lacerta agilis).
No strong correlations between serum cytokine levels, CMV serostatus and hand-grip strength in older subjects in the Berlin BASE-II cohort.
Noisy silence: non-coding RNA and heterochromatin formation at repetitive elements.
Non-coding RNAs: biological functions and applications.
Non-radioactive assay methods for the assessment of telomerase activity and telomere length.
Non-small cell lung cancer is susceptible to induction of DNA damage responses and inhibition of angiogenesis by telomere overhang oligonucleotides.
Noncanonical DNA secondary structures as drug targets: the prospect of the i-motif.
Noncanonical functions of telomerase: implications in telomerase-targeted cancer therapies.
Noncovalent interactions with SUMO and ubiquitin orchestrate distinct functions of the SLX4 complex in genome maintenance.
Nondestructive estimation of growth year in ginseng cultivars using the means of mathematical modeling on the basis of allometry.
Nonsense mutations in the shelterin complex genes ACD and TERF2IP in familial melanoma.
Nonsupportive parenting affects telomere length in young adulthood among African Americans: mediation through substance use.
NoRC silences rRNA genes, telomeres, and centromeres.
Normal and aging hair biology and structure 'aging and hair'.
Normal telomere length maintenance in Saccharomyces cerevisiae requires nuclear import of the ever shorter telomeres 1 (Est1) protein via the importin alpha pathway.
Not all biofluids are created equal: chewing over salivary diagnostics and the epigenome.
Not All DDRs Are Created Equal: Non-Canonical DNA Damage Responses.
Not merely quiescent: telomeres in quiescent HSCs.
Novel anticancer strategy aimed at targeting shelterin complexes by the induction of structural changes in telomeric DNA: hitting two birds with one stone.
Novel delivery system for T-oligo using a nanocomplex formed with an alpha helical peptide for melanoma therapy.
Novel function of the Fanconi anemia group J or RECQ1 helicase to disrupt protein-DNA complexes in a replication protein A-stimulated manner.
Novel H3K4me3 marks are enriched at human- and chimpanzee-specific cytogenetic structures.
Novel neuroendocrine and metabolic mechanism provides the patented platform for important rejuvenation therapies: targeted therapy of telomere attrition and lifestyle changes of telomerase activity with the timing of neuron-specific imidazole-containing d
Novel RNA- and FMRP-binding protein TRF2-S regulates axonal mRNA transport and presynaptic plasticity.
Novel telomere-anchored PCR approach for studying sexual stage telomeres in Aspergillus nidulans.
Nr0b1 is a negative regulator of Zscan4c in mouse embryonic stem cells.
NSC746364, a G-quadruplex-stabilizing agent, suppresses cell growth of A549 human lung cancer cells through activation of the ATR/Chk1-dependent pathway.
Nuclear bodies: new insights into assembly/dynamics and disease relevance.
Nuclear deformability and telomere dynamics are regulated by cell geometric constraints.
Nuclear pore complex evolution: a trypanosome Mlp analogue functions in chromosomal segregation but lacks transcriptional barrier activity.
Nuclear translocation of telomerase reverse transcriptase is a critical process in lymphatic metastasis of nasopharyngeal carcinoma.
Nuclear-cytoskeletal linkages facilitate cross talk between the nucleus and intercellular adhesions.
Nuclear-receptor-mediated telomere insertion leads to genome instability in ALT cancers.
Nuclease delivery: versatile functions of SLX4/FANCP in genome maintenance.
Nucleolar organization, ribosomal DNA array stability, and acrocentric chromosome integrity are linked to telomere function.
Nucleomorph and plastid genome sequences of the chlorarachniophyte Lotharella oceanica: convergent reductive evolution and frequent recombination in nucleomorph-bearing algae.
Nucleoplasmic bridges and acrocentric chromosome associations as early markers of exposure to low levels of ionising radiation in occupationally exposed hospital workers.
Nucleostemin rejuvenates cardiac progenitor cells and antagonizes myocardial aging.
Nucleotide sequences of an important functional gene hnRNPA2/B1 from Ailuropoda melanoleuca and Ursus thibetanus mupinensis and its potential value in phylogenetic study.
Number of Children and Telomere Length in Women: A Prospective, Longitudinal Evaluation.
NuRD-ZNF827 recruitment to telomeres creates a molecular scaffold for homologous recombination.
Nutrients, foods, dietary patterns and telomere length: Update of epidemiological studies and randomized trials.
Nutrigenomic programming of cardiovascular and metabolic diseases.
Nutriomes and personalised nutrition for DNA damage prevention, telomere integrity maintenance and cancer growth control.
Nutrition and lifestyle in healthy aging: the telomerase challenge.
Nutritional programming of coenzyme Q: potential for prevention and intervention?
Obesity and inflammation markers in relation to leukocyte telomere length in a cross-sectional study of persons with Barrett's esophagus.
Occurrence of Rabl-like telomere clustering in the holocentric chromosomes of the peach potato aphid Myzus persicae (Hemiptera; Aphididae).
Oligonucleotides and G-quadruplex stabilizers: targeting telomeres and telomerase in cancer therapy.
Olive Oil and the Hallmarks of Aging.
On being the right size: increased body size is associated with reduced telomere length under natural conditions.
On cross-sectional associations of leukocyte telomere length with cardiac systolic, diastolic and vascular function: the Asklepios study.
On telomeres long and short.
On the origin of Robertsonian fusions in nature: evidence of telomere shortening in wild house mice.
On the road with WRAP53β: guardian of Cajal bodies and genome integrity.
Opposite Effects of Early-Life Competition and Developmental Telomere Attrition on Cognitive Biases in Juvenile European Starlings.
Optimized Virtual Screening Workflow for the Identification of Novel G-Quadruplex Ligands.
Oral squamous cancer cell exploits hnRNP A1 to regulate cell cycle and proliferation.
Organic Pollutants and Telomere Length: A New Facet of Carcinogenesis.
Organismal stress, telomeres and life histories.
Organization, stability, and expression of the genome.
Organohalogenated contaminants in white-tailed eagle (Haliaeetus albicilla) nestlings: An assessment of relationships to immunoglobulin levels, telomeres and oxidative stress.
Osteo-/odontogenic differentiation of induced mesenchymal stem cells generated through epithelial-mesenchyme transition of cultured human keratinocytes.
Osteoarthritis and telomere shortening.
Osteoarthritis: SIRT6 prevents chondrocyte senescence and DNA damage.
osteoporosis
Over-expression of telomere binding factors (TRF1 & TRF2) in renal cell carcinoma and their inhibition by using SiRNA induce apoptosis, reduce cell proliferation and migration invitro.
Overexpression and promoter mutation of the TERT gene in malignant pleural mesothelioma.
Overexpression of human telomerase reverse transcriptase C-terminal polypeptide sensitizes HeLa cells to 5-fluorouracil‑induced growth inhibition and apoptosis.
Overexpression of Telomerase Reverse Transcriptase Induces Autism-like Excitatory Phenotypes in Mice.
Oxidative damage impact on aging and age-related diseases: drug targeting of telomere attrition and dynamic telomerase activity flirting with imidazole-containing dipeptides.
Oxidative damage in the progression of chronic liver disease to hepatocellular carcinoma: an intricate pathway.
Oxidative stress and its significant roles in neurodegenerative diseases and cancer.
Oxidative stress induces persistent telomeric DNA damage responsible for nuclear morphology change in mammalian cells.
Oxidative stress inhibits the proliferation, induces premature senescence and promotes a catabolic phenotype in human nucleus pulposus intervertebral disc cells.
Oxidative Stress-Mediated Skeletal Muscle Degeneration: Molecules, Mechanisms, and Therapies.
Oxidative stress, telomere shortening, and DNA methylation in relation to low-to-moderate occupational exposure to welding fumes.
P. berghei telomerase subunit TERT is essential for parasite survival.
p53 and hereditary cancer.
p53 pathway activation by telomere attrition in X-DC primary fibroblasts occurs in the absence of ribosome biogenesis failure and as a consequence of DNA damage.
p53-Dependent Senescence in Mesenchymal Stem Cells under Chronic Normoxia Is Potentiated by Low-Dose γ-Irradiation.
PAI-1-regulated extracellular proteolysis governs senescence and survival in Klotho mice.
Parental age effects on odor sensitivity in healthy subjects and schizophrenia patients.
Parental care influences leukocyte telomere length with gender specificity in parents and offsprings.
Parental influence on systemic sclerosis.
Paroxysmal nocturnal haemoglobinuria phenotype cells and leucocyte subset telomere length in childhood acquired aplastic anaemia.
Paroxysmal nocturnal hemoglobinuria and telomere length predicts response to immunosuppressive therapy in pediatric aplastic anemia.
PARP Inhibitor PJ34 Suppresses Osteogenic Differentiation in Mouse Mesenchymal Stem Cells by Modulating BMP-2 Signaling Pathway.
Partial knockdown of TRF2 increase radiosensitivity of human mesenchymal stem cells.
Paternal age and telomere length in twins: the germ stem cell selection paradigm.
Pathogenesis and molecular biology of a transmissible tumor in the Tasmanian devil.
Pathogenesis from the reactivation of chromosomally integrated human herpesvirus type 6: facts rather than fiction.
Pathogenesis of polycystic ovary syndrome: multifactorial assessment from the foetal stage to menopause.
Patients with multiple sclerosis show increased oxidative stress markers and somatic telomere length shortening.
Pattern of change in telomere length: possible predictor of cancer.
Patterns of rDNA and telomeric sequences diversification: contribution to repetitive DNA organization in Phyllostomidae bats.
PBMC telomerase activity, but not leukocyte telomere length, correlates with hippocampal volume in major depression.
PCDH10 Interacts With hTERT and Negatively Regulates Telomerase Activity.
Pediatric End-Stage Failing Hearts Demonstrate Increased Cardiac Stem Cells.
Perceived stress and telomere length: A systematic review, meta-analysis, and methodologic considerations for advancing the field.
Perifosine as a potential novel anti-telomerase therapy.
Perinatal complications and aging indicators by midlife.
Perinuclear tethers license telomeric DSBs for a broad kinesin- and NPC-dependent DNA repair process.
Peripheral blood leukocyte telomere length and mortality among 64,637 individuals from the general population.
Peripheral blood lymphocyte telomere length as a predictor of response to immunosuppressive therapy in childhood aplastic anemia.
Peripheral blood telomere content is greater in patients with endometriosis than in controls.
Peripheral telomere length and hippocampal volume in adolescents with major depressive disorder.
Persistent telomere cohesion triggers a prolonged anaphase.
Personalized evolutionary hypothesis in genomics and auxiliary lymph node through diverse subtelomeric signal profile.
Pessimistic orientation in relation to telomere length in older men: the VA normative aging study.
Pesticide Use and Relative Leukocyte Telomere Length in the Agricultural Health Study.
PGC-1α Modulates Telomere Function and DNA Damage in Protecting against Aging-Related Chronic Diseases.
Pharmacodynamics of telomerase inhibition and telomere shortening by noncytotoxic suramin.
Pharmacological activation of Rap1 antagonizes the endothelial barrier disruption induced by exotoxins ExoS and ExoT of Pseudomonas aeruginosa.
Pharmacological intervention strategies for affecting telomerase activity: Future prospects to treat cancer and degenerative disease
Phosphorylation of CDK2 at threonine 160 regulates meiotic pachytene and diplotene progression in mice.
Phys Ed: How Exercising Keeps Your Cells Young
Phys Ed: How Exercising Keeps Your Cells Young
Physical activity and telomere length in early stage breast cancer survivors.
Physical Activity, Physical Fitness, and Leukocyte Telomere Length: The Cardiovascular Health Study.
Physical Exercise Alleviates Health Defects, Symptoms, and Biomarkers in Schizophrenia Spectrum Disorder.
Physical Exercise Prevents Cellular Senescence in Circulating Leukocytes and in the Vessel Wall
Physical mapping of the 5S and 18S rDNA in ten species of Hypostomus Lacépède 1803 (Siluriformes: Loricariidae): evolutionary tendencies in the genus.
Pif1 regulates telomere length by preferentially removing telomerase from long telomere ends.
PinX1 is up-regulated and associated with poor patients' survival in gliomas.
PinX1, a telomere repeat-binding factor 1 (TRF1)-interacting protein, maintains telomere integrity by modulating TRF1 homeostasis, the process in which human telomerase reverse Transcriptase (hTERT) plays dual roles.
Placental membrane aging and HMGB1 signaling associated with human parturition.
Placental telomere length and risk of placental abruption.
Placental telomere length decreases with gestational age and is influenced by parity: a study of third trimester live-born twins.
Placental telomere shortening in stillbirth: a sign of premature senescence?
Plant alkaloid chelerythrine induced aggregation of human telomere sequence--a unique mode of association between a small molecule and a quadruplex.
Plasma irisin levels predict telomere length in healthy adults.
Plasma micronutrient levels and telomere length in children.
Plasma vitamin D biomarkers and leukocyte telomere length in men.
Platinum(II) phenanthroimidazole G-quadruplex ligand induces selective telomere shortening in A549 cancer cells.
PLCε mediated sustained signaling pathways.
Plumbagin alters telomere dynamics, induces DNA damage and cell death in human brain tumour cells.
PML induces compaction, TRF2 depletion and DNA damage signaling at telomeres and promotes their alternative lengthening.
PML is required for telomere stability in non-neoplastic human cells.
Polo-like Kinase 1 (Plk1) Up-regulates Telomerase Activity by Affecting Human Telomerase Reverse Transcriptase (hTERT) Stability.
Poly (ADP-ribose) polymerase 3 (PARP3), a potential repressor of telomerase activity.
Poly(A)-specific ribonuclease (PARN) mediates 3'-end maturation of the telomerase RNA component.
Poly(A)-specific ribonuclease deficiency impacts telomere biology and causes dyskeratosis congenita.
Poly(ADP-ribose)-binding promotes Exo1 damage recruitment and suppresses its nuclease activities.
Polychlorinated Biphenyls and Leukocyte Telomere Length: An Analysis of NHANES 1999-2002.
Polymerase I and transcript release factor (PTRF) regulates adipocyte differentiation and determines adipose tissue expandability.
Polymerase η suppresses telomere defects induced by DNA damaging agents.
Polymerases ε and ∂ repair dysfunctional telomeres facilitated by salt.
Polymorphisms within the Telomerase Reverse Transcriptase gene (TERT) in four breeds of dogs selected for difference in lifespan and cancer susceptibility.
Polysaccharides from medicinal herbs as potential therapeutics for aging and age-related neurodegeneration.
Pontin functions as an essential coactivator for Oct4-dependent lincRNA expression in mouse embryonic stem cells.
Poor prognosis of constitutive γ-H2AX expressing triple-negative breast cancers is associated with telomere length.
Population-specific association of genes for telomere-associated proteins with longevity in an Italian population.
Positive association of long telomeres with the invasive capacity of hepatocellular carcinoma cells.
Possible Benefit of Dietary Carnosine towards Depressive Disorders.
Possible technical and biological explanations for the 'parental telomere length inheritance discrepancy' enigma.
Posttranslational marks control architectural and functional plasticity of the nuclear pore complex basket.
POT1 loss-of-function variants predispose to familial melanoma.
POT1: a genetic link for familial glioma.
POT1a and components of CST engage telomerase and regulate its activity in Arabidopsis.
Pot1a prevents telomere dysfunction and ATM-dependent neuronal loss.
Potent Human Telomerase Inhibitors: Molecular Dynamic Simulations, Multiple Pharmacophore-Based Virtual Screening, and Biochemical Assays.
Potential of Telomerase in Age-Related Macular Degeneration-Involvement of Senescence, DNA Damage Response and Autophagy and a Key Role of PGC-1α
Potential Risks in the Paradigm of Basic to Translational Research: A Critical Evaluation of qPCR Telomere Size Techniques.
Preanalytical Conditions and DNA Isolation Methods Affect Telomere Length Quantification in Whole Blood.
Prediagnostic Obesity and Physical Inactivity Are Associated with Shorter Telomere Length in Prostate Stromal Cells.
Prediagnostic telomere length and risk of B-cell lymphoma-Results from the EPIC cohort study.
Predicting clinical outcome in feline oral squamous cell carcinoma: tumour initiating cells, telomeres and telomerase.
Predicting Risk at the End of the End: Telomere G-tail as a Biomarker.
Predictive and prognostic molecular markers for cholangiocarcinoma in Han Chinese population.
Predisposition to pediatric and hematologic cancers: a moving target.
Prelamin A accumulation and stress conditions induce impaired Oct-1 activity and autophagy in prematurely aged human mesenchymal stem cell.
Prelamin A accumulation in endothelial cells induces premature senescence and functional impairment.
Premature cardiac senescence in DahlS.Z-Lepr(fa)/Lepr(fa) rats as a new animal model of metabolic syndrome.
Premature senescence of T-cell subsets in axial spondyloarthritis.
Prenatal detection and characterization of a psu idic(8)(p23.3) which likely derived from nonallelic homologous recombination between two MYOM2-repeats.
Prenatal stress and newborn telomere length.
Prenatal undernutrition and leukocyte telomere length in late adulthood: the Dutch famine birth cohort study.
Prevalence of FA-D2 rare complementation group of Fanconi anemia in Serbia.
Preventing clonal evolutionary processes in cancer: Insights from mathematical models.
Prevention effects ameliorate the prospective association between nonsupportive parenting and diminished telomere length.
Prevention of Neointimal Hyperplasia by Local Application of Lentiviral Vectors Encoding Pin1 shRNA in Pluronic F127.
Primary Cytomegalovirus Infection Significantly Impacts Circulating T Cells in Kidney Transplant Recipients.
Pro-apoptotic and anti-proliferative effects of 3,3'-diindolylmethane in nasopharyngeal carcinoma cells via downregulation of telomerase activity.
Pro12Ala polymorphism of the PPARγ2 gene interacts with a mediterranean diet to prevent telomere shortening in the PREDIMED-NAVARRA randomized trial.
Processing by MRE11 is involved in the sensitivity of subtelomeric regions to DNA double-strand breaks.
Processing of semen by density gradient centrifugation selects spermatozoa with longer telomeres for assisted reproduction techniques.
Profile of Daniel E. Gottschling.
Profound parental bias associated with chromosome 14 acquired uniparental disomy indicates targeting of an imprinted locus.
Progerin reduces LAP2α-telomere association in Hutchinson-Gilford progeria.
Prognostic impact of telomere maintenance gene polymorphisms in hepatocellular carcinoma patients: some issues need to be clarified.
Prognostic impact of telomere maintenance gene polymorphisms on hepatocellular carcinoma patients with chronic hepatitis B.
Prognostic quality of activating TERT promoter mutations in glioblastoma: interaction with the rs2853669 polymorphism and patient age at diagnosis.
Prognostic significance of telomere maintenance mechanisms in pediatric high-grade gliomas.
Prognostic value of telomere function in gastric cancers with and without microsatellite instability.
Programmed Cell Death Genes Are Linked to Elevated Creatine Kinase Levels in Unhealthy Male Nonagenarians.
Prolonged expansion of human nucleus pulposus cells expressing human telomerase reverse transcriptase mediated by lentiviral vector.
Promoter polymorphism in the serotonin transporter (5-HTT) gene is significantly associated with leukocyte telomere length in Han Chinese.
Prospective coronary heart disease screening in asymptomatic Hodgkin lymphoma patients using coronary computed tomography angiography: results and risk factor analysis.
Prospective study of telomere length and LINE-1 methylation in peripheral blood cells: the role of B vitamins supplementation.
Prostaglandin E2 promotes features of replicative senescence in chronically activated human CD8+ T cells.
Prostaglandin E2 reduces the release and infectivity of new cell-free virions and cell-to-cell HIV-1 transfer.
Prostate stromal cell telomere shortening is associated with risk of prostate cancer in the placebo arm of the Prostate Cancer Prevention Trial.
Protective effects of ginsenoside Rg1 on aging Sca-1⁺ hematopoietic cells.
Protein phosphatase 1 recruitment by Rif1 regulates DNA replication origin firing by counteracting DDK activity.
Protein profiling reveals consequences of lifestyle choices on predicted biological aging.
Proteins induced by telomere dysfunction are associated with human IgA nephropathy.
Proteomic and microRNA data clarifying the effects of telomere shortening on cancer cells.
Proteomics of yeast telomerase identified Cdc48-Npl4-Ufd1 and Ufd4 as regulators of Est1 and telomere length.
Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1.
Protocol for a systematic review of the association between chronic stress during the life course and telomere length.
Psychiatric disorders and leukocyte telomere length: Underlying mechanisms linking mental illness with cellular aging.
Psychosomatic medicine in the 21st century: understanding mechanisms and barriers to utilization.
PTOP and TRF1 help enhance the radio resistance in breast cancer cell.
Publications
Pulmonary fibrosis associated with TINF2 gene mutation: is somatic reversion required?
Pulmonary fibrosis in dyskeratosis congenita: report of 2 cases.
Pure 9p trisomy derived from a terminal balanced unreciprocal translocation.
Putting Off the Inevitable.
Q-FISH measurement of hepatocyte telomere lengths in donor liver and graft after pediatric living-donor liver transplantation: donor age affects telomere length sustainability.
Q&A: End-game winner.
QnAs with Cynthia J. Burrows.
Quality control: Genome maintenance in pluripotent stem cells.
Quantitative Fitness Analysis Identifies exo1∆ and Other Suppressors or Enhancers of Telomere Defects in Schizosaccharomyces pombe.
Quantitative fluorescence in situ hybridization measurement of telomere length in skin with/without sun exposure or actinic keratosis.
Quantitative telomerase enzyme activity determination using droplet digital PCR with single cell resolution.
Quantitative trait association study for mean telomere length in the South Asian genomes.
Questioning causal involvement of telomeres in aging.
Quiescence-induced LncRNAs trigger H4K20 trimethylation and transcriptional silencing.
Race-Ethnicity, Poverty, Urban Stressors, and Telomere Length in a Detroit Community-based Sample.
Race-related health disparities and biological aging: does rate of telomere shortening differ across blacks and whites?
Race, Ethnicity, Psychosocial Factors, and Telomere Length in a Multicenter Setting.
Rad51-dependent aberrant chromosome structures at telomeres and ribosomal DNA activate the spindle assembly checkpoint.
Rad59-facilitated acquisition of Y' elements by short telomeres delays the onset of senescence.
Radiation hybrid map of buffalo chromosome 7 detects a telomeric inversion compared to cattle chromosome 6.
Radiation Sensitivity and Radiation Necrosis in the Short Telomere Syndromes.
Radiation-induced telomere length variations in normal and in Nijmegen Breakage Syndrome cells.
RAP1 GTPase overexpression is associated with cervical intraepithelial neoplasia.
Rap1 induces cytokine production in pro-inflammatory macrophages through NFκB signaling and is highly expressed in human atherosclerotic lesions.
Rap1 is indispensable for TRF2 function in etoposide-induced DNA damage response in gastric cancer cell line.
Rap1 signaling in endothelial barrier control.
RAP1-mediated MEK/ERK pathway defects in Kabuki syndrome.
Rapid analysis of chromosome aberrations in mouse B lymphocytes by PNA-FISH.
Rapid growth accelerates telomere attrition in a transgenic fish.
Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1.
Rare missense variants in POT1 predispose to familial cutaneous malignant melanoma.
Rare variants in RTEL1 are associated with familial interstitial pneumonia.
Rasa3 controls megakaryocyte Rap1 activation, integrin signaling and differentiation into proplatelet.
Rate of telomere shortening and cardiovascular damage: a longitudinal study in the 1946 British Birth Cohort.
Rate of telomere shortening and metabolic and cardiovascular risk factors: a longitudinal study in the 1934-44 Helsinki Birth Cohort Study.
Rationale and design of RETAIN study: Rosuvastatin Effect on Telomere-telomerase system in Acute coronary syndrome patients undergoing percutaneous coronary Intervention.
RE: Germline Mutations in Shelterin Complex Genes Are Associated With Familial Glioma.
Re: Telomere Homeostasis is Compromised in Spermatocytes from Patients with Idiopathic Infertility.
Re: Telomere length as a risk factor for hereditary prostate cancer.
Re: telomere length influences cancer cell differentiation in vivo.
RE: The Effect on Melanoma Risk of Genes Previously Associated With Telomere Length.
Reactive oxygen species contribute to dysfunction of bone marrow hematopoietic stem cells in aged C57BL/6 J mice.
Reactive oxygen species promotes cellular senescence in normal human epidermal keratinocytes through epigenetic regulation of p16(INK4a.).
Real-Time Evolution of a Subtelomeric Gene Family in Candida albicans.
Real-Time, Quantitative Lighting-up Detection of Telomerase in Urines of Bladder Cancer Patients by AIEgens.
Recognition and binding of human telomeric G-quadruplex DNA by unfolding protein 1.
Recognition of chelerythrine to human telomeric DNA and RNA G-quadruplexes.
Recombination-independent mechanisms and pairing of homologous chromosomes during meiosis in plants.
Recombineering linear BACs.
Recombinogenic telomeres in diploid Sorex granarius (Soricidae, Eulipotyphla) fibroblast cells.
Reconstructing the in vivo dynamics of hematopoietic stem cells from telomere length distributions.
Reconstruction of canine diffuse large B-cell lymphoma gene regulatory network: detection of functional modules and hub genes.
Recovering complete mitochondrial genome sequences from RNA-Seq: A case study of Polytomella non-photosynthetic green algae.
RecQ helicases and PARP1 team up in maintaining genome integrity.
RecQ-core of BLM unfolds telomeric G-quadruplex in the absence of ATP.
RECQ1 interacts with FEN-1 and promotes binding of FEN-1 to telomeric chromatin.
Recurrent TERT promoter mutations identified in a large-scale study of multiple tumour types are associated with increased TERT expression and telomerase activation.
Red blood cell distribution width: A simple parameter with multiple clinical applications.
Red blood cells open promising avenues for longitudinal studies of ageing in laboratory, non-model and wild animals.
Red light interferes in UVA-induced photoaging of human skin fibroblast cells.
Reduced fetal telomere length in gestational diabetes.
Reduced T-Cell Thymic Export Reflected by sj-TREC in Patients with Coronary Artery Disease.
Reduced telomere length in neurodegenerative disorders may suggest shared biology.
Reduced telomere length in subjects with dementia and diabetes mellitus type 2 is independent of apolipoprotein E4 genotype.
Reduced telomere length is not associated with early signs of vascular aging in young men born after intrauterine growth restriction: a paradox?
Regulation of Elg1 activity by phosphorylation.
Regulation of Ku-DNA association by Yku70 C-terminal tail and SUMO modification.
Regulation of Telomere Length Requires a Conserved N-Terminal Domain of Rif2 in Saccharomyces cerevisiae.
Regulation of telomeric i-motif stability by 5-methylcytosine and 5-hydroxymethylcytosine modification.
Regulator of telomere elongation helicase 1 (RTEL1) rs6010620 polymorphism contribute to increased risk of glioma.
Regulatory effects of WRAP53 on radiosensitivity of laryngeal squamous cell carcinoma cells.
Relationship between Initial Telomere Length, Initial Telomerase Activity, Age, and Replicative Capacity of Nucleus Pulposus Chondrocytes in Human Intervertebral Discs: What Is a Predictor of Replicative Potential?
Relationship between leukocyte telomere length and personality traits in healthy subjects.
Relationship between leukocyte telomere length, telomerase activity, and hippocampal volume in early aging.
Relationship Between Mean Leucocyte Telomere Length and Measures of Allostatic Load in US Reproductive-Aged Women, NHANES 1999-2002.
Relationships of pulmonary function, inflammation, and T-cell activation and senescence in an HIV-infected cohort.
Relative Leukocyte Telomere Length, Hematological Parameters and Anemia - Data from the Berlin Aging Study II (BASE-II).
Relative telomere length is associated with a functional polymorphism in the monoamine oxidase A gene in a South American sample.
Relevance of telomere/telomerase system impairment in early stage chronic lymphocytic leukemia.
Religion, spirituality, and health: a review and update.
Religious Involvement and Telomere Length in Women Family Caregivers.
Renal phenotype of young and old telomerase-deficient mice.
Repair of DNA double-strand breaks by templated nucleotide sequence insertions derived from distant regions of the genome.
Repair of O6-methylguanine adducts in human telomeric G-quadruplex DNA by O6-alkylguanine-DNA alkyltransferase.
Repeated stressors in adulthood increase the rate of biological ageing.
Replicating through telomeres: a means to an end.
Replication intermediates of the linear mitochondrial DNA of Candida parapsilosis suggest a common recombination based mechanism for yeast mitochondria.
Replication of the results of genome-wide and candidate gene association studies on telomere length in a Korean population.
Replication Stress and Telomere Dysfunction Are Present in Cultured Human Embryonic Stem Cells.
Reply to Drury and Theall: No evidence of population stratification.
Reply: telomerase makes connections between pulmonary fibrosis and emphysema.
Reply: To PMID 23907815.
Repression of hTERT transcription by the introduction of chromosome 3 into human oral squamous cell carcinoma.
Reproducibility of Telomere Length Assessment--An International Collaborative Study.
Reproducibility of telomere length assessment: an international collaborative study.
Reproducibility of telomere length assessment: Authors' Response to Damjan Krstajic and Ljubomir Buturovic.
Reproducibility of telomere length assessment.
Reprogramming suppresses premature senescence phenotypes of Werner syndrome cells and maintains chromosomal stability over long-term culture.
Reprogramming the genetic code: The emerging role of ribosomal frameshifting in regulating cellular gene expression.
Requirement of the FATC domain of protein kinase Tel1 for localization to DNA ends and target protein recognition.
Resistance training enhances insulin suppression of endogenous glucose production in elderly women.
Resistance training improves skeletal muscle insulin sensitivity in elderly offspring of overweight and obese mothers.
Resolution of telomere associations by TRF1 cleavage in mouse embryonic stem cells.
Response to androgen therapy in patients with dyskeratosis congenita.
Response.
Response.
Responses to telomere erosion in plants.
Retroviral insertional mutagenesis in telomerase-immortalized hepatocytes identifies RIPK4 as novel tumor suppressor in human hepatocarcinogenesis.
Revealing the pathogenic and aging-related mechanisms of the enigmatic idiopathic pulmonary fibrosis. an integral model.
Reverse Your Aging Process
Reversibility of Defective Hematopoiesis Caused by Telomere Shortening in Telomerase Knockout Mice.
Reversible transformation and de-differentiation of human cells derived from induced pluripotent stem cell teratomas.
Review of poly (ADP-ribose) polymerase (PARP) mechanisms of action and rationale for targeting in cancer and other diseases.
RFPL3 and CBP synergistically upregulate hTERT activity and promote lung cancer growth.
RHPS4 G-quadruplex ligand induces anti-proliferative effects in brain tumor cells.
Ribosomal DNA clusters and telomeric (TTAGG)n repeats in blue butterflies (Lepidoptera, Lycaenidae) with low and high chromosome numbers.
Ribosomes in the balance: structural equilibrium ensures translational fidelity and proper gene expression.
Riccardin D, a macrocyclic bisbibenzy, inhibits human breast cancer growth through the suppression of telomerase activity.
Rif1 controls DNA replication by directing Protein Phosphatase 1 to reverse Cdc7-mediated phosphorylation of the MCM complex.
Rif1 controls DNA replication timing in yeast through the PP1 phosphatase Glc7.
Rif1 Is Required for Resolution of Ultrafine DNA Bridges in Anaphase to Ensure Genomic Stability.
Rif1 maintains telomere length homeostasis of ESCs by mediating heterochromatin silencing.
Rif1 regulates initiation timing of late replication origins throughout the S. cerevisiae genome.
RIF1: a novel regulatory factor for DNA replication and DNA damage response signaling.
Risk of multiple myeloma is associated with polymorphisms within telomerase genes and telomere length.
RNAi-assisted genome evolution in Saccharomyces cerevisiae for complex phenotype engineering.
RNaseH1 regulates TERRA-telomeric DNA hybrids and telomere maintenance in ALT tumour cells.
RNF4 interacts with both SUMO and nucleosomes to promote the DNA damage response.
Robust DNA Damage Response and Elevated Reactive Oxygen Species in TINF2-Mutated Dyskeratosis Congenita Cells.
Role for telomerase in pulmonary hypertension.
Role of arterial telomere dysfunction in hypertension: relative contributions of telomere shortening and telomere uncapping.
Role of Sirt3 in mitochondrial biogenesis and developmental competence of human in vitro matured oocytes.
Role of telomere length in interindividual variation in cardiovascular protection in hypertensive patients.
Role of telomeres in vascular senescence
Role of TERRA in the regulation of telomere length.
Role of Tet proteins in enhancer activity and telomere elongation.
Role of Zscan4 in secondary murine iPSC derivation mediated by protein extracts of ESC or iPSC.
Roles for Histone Acetylation in Regulation of Telomere Elongation and Two-cell State in Mouse ES Cells.
RPA prevents G-rich structure formation at lagging-strand telomeres to allow maintenance of chromosome ends.
RPA-1 from Leishmania amazonensis (LaRPA-1) structurally differs from other eukaryote RPA-1 and interacts with telomeric DNA via its N-terminal OB-fold domain.
RTEL1: functions of a disease-associated helicase.
Saccharomyces cerevisiae Rif1 cooperates with MRX-Sae2 in promoting DNA-end resection.
Salivary Telomere Length and Lung Function in Adolescents Born Very Preterm: A Prospective Multicenter Study.
Sarcoid-derived fibroblasts: links between genomic instability, energy metabolism and senescence.
Satellite DNA in Plants: More than Just Rubbish.
Seasonal variation of peripheral blood leukocyte telomere length in Costa Rica: A population-based observational study.
Secretory Breast Carcinoma: A Histopathologic and Genomic Spectrum Characterized by a Joint Specific ETV6-NTRK3 Gene Fusion.
Select aging biomarkers based on telomere length and chronological age to build a biological age equation.
Select neurocognitive impairment in HIV-infected women: associations with HIV viral load, hepatitis C virus, and depression, but not leukocyte telomere length.
Selected Studies & White Papers
Selective increase in subtelomeric DNA methylation: an epigenetic biomarker for malignant glioma.
Selective protection of zidovudine-induced DNA-damage by the antioxidants WR-1065 and tempol.
senescence
Senescence and apoptosis block hematopoietic activation of quiescent hematopoietic stem cells with short telomeres.
Senescence associated secretory phenotype profile from primary lung mice fibroblasts depends on the senescence induction stimuli.
Senescence effects of Angelica sinensis polysaccharides on human acute myelogenous leukemia stem and progenitor cells.
Senescence in the wild: Insights from a long-term study on Seychelles warblers.
Senescence is involved in the pathogenesis of chronic obstructive pulmonary disease through effects on telomeres and the anti-aging molecule fibroblast growth factor 23.
Senescence-associated secretory phenotype and its possible role in chronic obstructive pulmonary disease.
Senescence-Induced Oxidative Stress Causes Endothelial Dysfunction.
Senescent cells: SASPected drivers of age-related pathologies.
Separation of Quadruplex Polymorphism in DNA Sequences by Reversed-Phase Chromatography.
Sequence analysis of the PIP5K locus in Eimeria maxima provides further evidence for eimerian genome plasticity and segmental organization.
Sequence variation in telomerase reverse transcriptase (TERT) as a determinant of risk of cardiovascular disease: the Atherosclerosis Risk in Communities (ARIC) study.
SET1A Cooperates With CUDR to Promote Liver Cancer Growth and Hepatocyte-like Stem Cell Malignant Transformation Epigenetically.
Set5 and Set1 cooperate to repress gene expression at telomeres and retrotransposons.
Setting the trajectory: racial disparities in newborn telomere length.
Seventy years after the siege of Leningrad: does early life famine still affect cardiovascular risk and aging?
Sex determination in Madagascar geckos of the genus Paroedura (Squamata: Gekkonidae): are differentiated sex chromosomes indeed so evolutionary stable?
Sex difference in leukocyte telomere length is ablated in opposite-sex co-twins.
Sex- and season-dependent differences in telomere length and telomerase activity in the leaves of ash and willow.
Sex-dependent effects of nutrition on telomere dynamics in zebra finches (Taeniopygia guttata).
Sex-Specific Association between Longitudinal Changes in Adiposity, FTO rs9939609 Polymorphism, and Leukocyte Telomere Length.
Sgs1 and Sae2 promote telomere replication by limiting accumulation of ssDNA.
Shading the TRF2 recruiting function: a new horizon in drug development.
Shared environmental factors associated with telomere length maintenance in elderly male twins
Shelterin proteins and cancer.
Shifts in rDNA levels act as a genome buffer promoting chromosome homeostasis.
Short and long telomeres increase risk of amnestic mild cognitive impairment.
Short communication: Ovine leukocyte telomere length is associated with variation in the cortisol response to systemic bacterial endotoxin challenge.
Short homologies efficiently generate detectable homologous recombination events.
Short Leukocyte Telomere Length Is Associated With Cardioembolic Stroke Risk in Patients With Atrial Fibrillation.
Short leukocyte telomere length is associated with obesity in American Indians: the Strong Heart Family study.
Short leukocyte telomere length predicts incidence and progression of carotid atherosclerosis in American Indians: the Strong Heart Family Study.
Short leukocyte telomere length predicts poor prognosis and indicates altered immune functions in colorectal cancer patients.
Short leukocyte telomere length predicts risk of diabetes in american indians: the strong heart family study.
Short Peptides and Telomere Length Regulator Hormone Irisin.
Short telomere length in peripheral blood leukocyte predicts poor prognosis and indicates an immunosuppressive phenotype in gastric cancer patients.
Short telomere length is associated with arterial aging in patients with type 2 diabetes mellitus.
Short telomeres and chromosome instability prior to histologic malignant progression and cytogenetic aneuploidy in papillary urothelial neoplasms.
Short Telomeres in Key Tissues Initiate Local and Systemic Aging in Zebrafish.
Short telomeres in pulmonary fibrosis: from genetics to clinical significance.
Short telomeres, telomeropathy, and subclinical extrapulmonary organ damage in patients with interstitial lung disease.
Short telomeres: a repeat offender in IPF.
Shortened leukocyte telomere length in patients with schizophrenia is related to disease status.
Shortened telomere in unremitted schizophrenia.
Shortened telomere length in patients with depression: A meta-analytic study.
Shortened telomere length in white matter oligodendrocytes in major depression: potential role of oxidative stress.
Shortened Telomere Length Is Associated with Increased Risk of Cancer: A Meta-Analysis
Shortened telomere length is associated with paroxysmal atrial fibrillation among cardiovascular patients enrolled in the Intermountain Heart Collaborative Study.
Shortened Telomeres in Families With a Propensity to Autism.
Shorter Ends, Faster End? Leukocyte Telomere Length and Mortality Among Older Taiwanese.
Shorter leukocyte telomere length is associated with adverse COVID-19 outcomes: A cohort study in UK Biobank
Shorter leukocyte telomere length is independently associated with poor survival in patients with bladder cancer.
Shorter telomere length in peripheral blood leukocytes is associated with childhood autism.
Shorter telomere length is linked to brain atrophy and white matter hyperintensities.
Shorter telomere length predicts poorer immunological recovery in virologically suppressed HIV-1-infected patients treated with combined antiretroviral therapy.
Shorter telomere lengths in patients with severe COVID-19 disease
Shorter telomeres correlate with an increase in the number of uniparental disomies in patients with chronic lymphocytic leukemia.
Shorter telomeres in peripheral blood mononuclear cells from older persons with sarcopenia: results from an exploratory study.
Shorter telomeres with high telomerase activity are associated with raised allostatic load and impoverished psychosocial resources.
Significance of telomere capture in myelodysplastic syndromes.
Silencing is noisy: population and cell level noise in telomere-adjacent genes is dependent on telomere position and sir2.
Silkworm HP1a transcriptionally enhances highly expressed euchromatic genes via association with their transcription start sites.
Simultaneous copy number losses within multiple subtelomeric regions in early-onset type 2 diabetes mellitus.
Simultaneous quantification of alternatively spliced transcripts in a single droplet digital PCR reaction.
Single-cell telomere-length quantification couples telomere length to meristem activity and stem cell development in Arabidopsis.
Single-molecule analysis of thymine dimer-containing G-quadruplexes formed from the human telomere sequence.
Single-molecule investigation of G-quadruplex folds of the human telomere sequence in a protein nanocavity.
Single-molecule real-time detection of telomerase extension activity.
Single-strand DNA-binding protein SSB1 facilitates TERT recruitment to telomeres and maintains telomere G-overhangs.
SIRT1 ameliorates age-related senescence of mesenchymal stem cells via modulating telomere shelterin.
SIRT1 is necessary for proficient telomere elongation and genomic stability of induced pluripotent stem cells.
SIRT1: role in cardiovascular biology.
SIRT6 protein deacetylase interacts with MYH DNA glycosylase, APE1 endonuclease, and Rad9-Rad1-Hus1 checkpoint clamp.
Skeletal muscle ceramide species in men with abdominal obesity.
Skeletal muscle telomere length in healthy, experienced, endurance runners
Skeletal muscle telomere length in healthy, experienced, endurance runners
Skin pentosidine and telomere length do not covary with age in a long-lived seabird.
Sleep
SLX4 contributes to telomere preservation and regulated processing of telomeric joint molecule intermediates.
Smaller and larger deletions of the Williams Beuren syndrome region implicate genes involved in mild facial phenotype, epilepsy and autistic traits.
SMARCAL1 maintains telomere integrity during DNA replication.
SMARCAL1 Resolves Replication Stress at ALT Telomeres.
SMC1B is present in mammalian somatic cells and interacts with mitotic cohesin proteins.
Smg6/Est1 licenses embryonic stem cell differentiation via nonsense-mediated mRNA decay.
Smoking accelerates aging of the small airway epithelium.
Smoking and perceived stress in relation to short salivary telomere length among caregivers of children with disabilities.
Smoking habits and leukocyte telomere length dynamics among older adults: Results from the ESTHER cohort.
Social disadvantage, genetic sensitivity, and children's telomere length.
Social isolation shortens telomeres in African Grey parrots (Psittacus erithacus erithacus).
Social stressors associated with age-related T lymphocyte percentages in older US adults: Evidence from the US Health and Retirement Study
Social support sources matter: Increased cellular aging among adults with unsupportive spouses.
Socioecological variables predict telomere length in wild spotted hyenas.
Soda and cell aging: associations between sugar-sweetened beverage consumption and leukocyte telomere length in healthy adults from the National Health and Nutrition Examination Surveys.
Soluble CD163 is associated with shortened telomere length in HIV-infected patients.
Solution structure of telomere binding domain of AtTRB2 derived from Arabidopsis thaliana.
Somatic mutations found in the healthy blood compartment of a 115-yr-old woman demonstrate oligoclonal hematopoiesis.
Somatic mutations identify a subgroup of aplastic anemia patients who progress to myelodysplastic syndrome.
Somatotrope GHRH/GH/IGF-1 axis at the crossroads between immunosenescence and frailty.
SORBS2 transcription is activated by telomere position effect-over long distance upon telomere shortening in muscle cells from patients with facioscapulohumeral dystrophy.
Spatial distribution of centromeres and telomeres at interphase varies among Brachypodium species.
Spatial organization of bacterial chromosomes.
Spatial reorganization of telomeres in long-lived quiescent cells.
Specific alkylation of human telomere repeat sequences by a tandem-hairpin motif of pyrrole-imidazole polyamides with indole-seco-CBI.
Specific features in linear and spatial organizations of pericentromeric heterochromatin regions in polytene chromosomes of the closely related species Drosophila virilis and D. kanekoi (Diptera: Drosophilidae).
Specific genomic aberrations predict survival, but low mutation rate in cancer hot spots, in clear cell renal cell carcinoma.
Specific Localization of the Drosophila Telomere Transposon Proteins and RNAs, Give Insight in Their Behavior, Control and Telomere Biology in This Organism.
Spectroscopic investigation on the interaction of copper porphyrazines and phthalocyanine with human telomeric G-quadruplex DNA.
Sperm telomere length is positively associated with the quality of early embryonic development.
Spermatozoa telomeres determine telomere length in early embryos and offspring.
Spontaneous tumor development in bone marrow-rescued DNA-PKcs(3A/3A) mice due to dysfunction of telomere leading strand deprotection.
Sports and Exercise at Different Ages and Leukocyte Telomere Length in Later Life--Data from the Berlin Aging Study II (BASE-II).
Spring loading a pre-cleavage intermediate for hairpin telomere formation.
Stabilization of mini-chromosome segregation during mitotic growth by overexpression of YCR041W and its application to chromosome engineering in Saccharomyces cerevisiae.
Stable cellular senescence is associated with persistent DDR activation.
Stand up for health--avoiding sedentary behaviour might lengthen your telomeres: secondary outcomes from a physical activity RCT in older people.
Standardization and safety of alveolar bone-derived stem cell isolation.
Star-shaped tetraspermine enhances cellular uptake and cytotoxicity of T-oligo in prostate cancer cells.
Starting with a handicap: effects of asynchronous hatching on growth rate, oxidative stress and telomere dynamics in free-living great tits.
State Institution "National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine" - research activities and scientific advance in 2013.
State Institution "National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine" - research activities and scientific advance in 2014.
Stem and progenitor cell division kinetics during postnatal mouse mammary gland development.
stem cell
Stem cell senescence. Effects of REAC technology on telomerase-independent and telomerase-dependent pathways.
Stem cells and aberrant signaling of molecular systems in skin aging.
Stn1 is critical for telomere maintenance and long-term viability of somatic human cells.
Stochastic simulations of normal aging and Werner's syndrome.
Strand exchange of telomeric DNA catalyzed by the Werner syndrome protein (WRN) is specifically stimulated by TRF2.
Streptococcus pneumoniae ClpL modulates adherence to A549 human lung cells through Rap1/Rac1 activation.
stress
Stress and telomere shortening among central Indian conservation refugees.
Stress exposure in early post-natal life reduces telomere length: an experimental demonstration in a long-lived seabird.
Stress induced premature senescence: a new culprit in ovarian tumorigenesis?
Stress induced telomere shortening: longer life with less mutations?
Stress responsive biochemical anabolic/catabolic ratio and telomere length in older adults.
Stress signaling from human mammary epithelial cells contributes to phenotypes of mammographic density.
Stressful life events and leukocyte telomere attrition in adulthood: a prospective population-based cohort study.
Stromal cell-derived factor 1 as a biomarker of heart failure and mortality risk.
Strong association between long and heterogeneous telomere length in blood lymphocytes and bladder cancer risk in Egyptian.
Structural alterations of skeletal muscle in copd.
Structural and biophysical characterization of murine rif1 C terminus reveals high specificity for DNA cruciform structures.
Structural and numerical changes of chromosome X in patients with esophageal atresia.
Structural basis for phosphorylation-dependent recruitment of Tel2 to Hsp90 by Pih1.
Structural Basis of Telomerase Inhibition by the Highly Specific BIBR1532.
Structural chromosome abnormalities, increased DNA strand breaks and DNA strand break repair deficiency in dermal fibroblasts from old female human donors.
Structural Features of the Telomerase RNA Gene in the Naked Mole Rat Heterocephalus glaber.
Structural Insight into the interaction of Flavonoids with Human Telomeric Sequence.
Structure of Est3 reveals a bimodal surface with differential roles in telomere replication.
Structure of human Bloom's syndrome helicase in complex with ADP and duplex DNA.
Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions.
Structure of the Rad50 DNA double-strand break repair protein in complex with DNA.
Studies on non-covalent interaction of coumarin attached pyrimidine and 1-methyl indole 1,2,3 triazole analogues with intermolecular telomeric G-quadruplex DNA using ESI-MS and spectroscopy.
Study of the association of total and differential white blood cell counts with geriatric conditions, cardio-vascular diseases, seric IL-6 levels and telomere length.
Study on the Dynamic Biological Characteristics of Sca-1(+) Hematopoietic Stem and Progenitor Cell Senescence.
Study Template Page
Subclinical carotid atherosclerosis and early vascular aging from long-term low-dose ionizing radiation exposure: a genetic, telomere, and vascular ultrasound study in cardiac catheterization laboratory staff.
Substantial telomere shortening in the substantia nigra of telomerase-deficient mice does not increase susceptibility to MPTP-induced dopamine depletion.
Substrate specificity of the MUS81-EME2 structure selective endonuclease.
Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase.
Subtelomeric CTCF and cohesin binding site organization using improved subtelomere assemblies and a novel annotation pipeline.
Subtelomeric demethylation deregulated hTERT expression, telomerase activity, and telomere length in four nasopharyngeal carcinoma cell lines.
Subtelomeric p53 binding prevents accumulation of DNA damage at human telomeres.
Successful treatment with rituximab and mycophenolate mofetil of refractory autoimmune hemolytic anemia post-hematopoietic stem cell transplant for dyskeratosis congenita due to TINF2 mutation.
SUMOylation regulates telomere length by targeting the shelterin subunit Tpz1(Tpp1) to modulate shelterin-Stn1 interaction in fission yeast.
Super DNAging-New insights into DNA integrity, genome stability and telomeres in the oldest old.
Suppression of OsKu80 results in defects in developmental growth and increased telomere length in rice (Oryza sativa L.).
Suppression of OsRAD51D results in defects in reproductive development in rice (Oryza sativa L.).
Suppression of PinX1 resulted in telomere dysfunction and enhanced radiosensitivity in osteosarcoma cell lines.
Suppression of subtelomeric VSG switching by Trypanosoma brucei TRF requires its TTAGGG repeat-binding activity.
Suppression of telomere-binding protein TPP1 resulted in telomere dysfunction and enhanced radiation sensitivity in telomerase-negative osteosarcoma cell line.
Suppression of the alternative lengthening of telomere pathway by the chromatin remodelling factor ATRX.
Suppression of the DHX9 helicase induces premature senescence in human diploid fibroblasts in a p53-dependent manner.
Suppressor of Ty homolog-5, a novel tumor-specific human telomerase reverse transcriptase promoter-binding protein and activator in colon cancer cells.
Surface Enhanced Raman Scattering Based in Situ Hybridization Strategy for Telomere Length Assessment.
SVA retrotransposon insertion-associated deletion represents a novel mutational mechanism underlying large genomic copy number changes with non-recurrent breakpoints.
Synaptonemal complex extension from clustered telomeres mediates full-length chromosome pairing in Schmidtea mediterranea.
Synergetic Effects of PARP Inhibitor AZD2281 and Cisplatin in Oral Squamous Cell Carcinoma in Vitro and in Vivo.
Synergistic tumor suppression by combined inhibition of telomerase and CDKN1A.
Synthesis and Evaluation of DNA Based Quantum Dot Fluorescence In Situ Hybridization (FISH) Probe for Telomere Detection.
Synthetic cytotoxicity: digenic interactions with TEL1/ATM mutations reveal sensitivity to low doses of camptothecin.
Systematic review of the association between chronic social stress and telomere length: A life course perspective.
T cells and their cytokines in persistent stimulation of the immune system.
T-cell ageing in end-stage renal disease patients: Assessment and clinical relevance.
T-oligo as an anticancer agent in colorectal cancer.
TALEN gene knockouts reveal no requirement for the conserved human shelterin protein Rap1 in telomere protection and length regulation.
Tandem repeats and G-rich sequences are enriched at human CNV breakpoints.
Tankyrase 1 polymorphism associated with an increased risk in developing non-small cell lung cancer in a Chinese population: a proof-of-principle study.
Tankyrase inhibition impairs directional migration and invasion of lung cancer cells by affecting microtubule dynamics and polarity signals.
Tankyrase inhibitors as therapeutic targets for cancer.
Tankyrases: structure, function and therapeutic implications in cancer.
Targeted DNA damage at individual telomeres disrupts their integrity and triggers cell death.
Targeted next-generation sequencing of cancer genes identified frequent TP53 and ATRX mutations in leiomyosarcoma.
Targeted therapies: DNA polymerase θ-a new target for synthetic lethality?
Targeting BRCA1 and BRCA2 Deficiencies with G-Quadruplex-Interacting Compounds.
Targeting cathepsin B by cycloastragenol enhances antitumor immunity of CD8 T cells via inhibiting MHC-I degradation
Targeting DNA-PKcs and telomerase in brain tumour cells.
Targeting G-Quadruplex DNA Structures by EMICORON Has a Strong Antitumor Efficacy against Advanced Models of Human Colon Cancer.
Targeting homologous recombination and telomerase in Barrett's adenocarcinoma: impact on telomere maintenance, genomic instability and tumor growth.
Targeting of DNA Damage Signaling Pathway Induced Senescence and Reduced Migration of Cancer cells.
Targeting of P-Element Reporters to Heterochromatic Domains by Transposable Element 1360 in Drosophila melanogaster.
Targeting telomere maintenance mechanisms in cancer therapy.
Tcstv1 and Tcstv3 elongate telomeres of mouse ES cells.
Teenage acne and cancer risk in US women: A prospective cohort study.
Tel1ATM dictates the replication timing of short yeast telomeres.
Telomerase abrogates aneuploidy-induced telomere replication stress, senescence and cell depletion.
Telomerase activates transcription of cyclin D1 gene through the interaction with NOL1.
Telomerase Activating Supplements
telomerase activation
Telomerase activation after recruitment in fission yeast.
Telomerase activation by genomic rearrangements in high-risk neuroblastoma.
Telomerase activation: a potential key modulator for human healthspan and longevity.
Telomerase activity analyzed with TRAP in situ provides additional information in effusions remaining equivocal after immunocytochemistry and hyaluronan analysis.
Telomerase activity and telomere length in Daphnia.
Telomerase Activity and Telomere Length in Human Benign Prostatic Hyperplasia Stem-like Cells and Their Progeny Implies the Existence of Distinct Basal and Luminal Cell Lineages.
Telomerase activity and telomere length in male germ cells.
Telomerase Activity in Articular Chondrocytes Is Lost after Puberty.
Telomerase activity in the various regions of mouse brain: non-radioactive telomerase repeat amplification protocol (TRAP) assay.
Telomerase activity is more significant for predicting the outcome of IVF treatment than telomere length in granulosa cells.
Telomerase activity-independent function of telomerase reverse transcriptase is involved in acrylamide-induced neuron damage.
Telomerase as a "stemness" enzyme.
Telomerase as a cancer target. Development of new molecules.
Telomerase Deficiency Causes Alveolar Stem Cell Senescence-associated Low-grade Inflammation in Lungs.
Telomerase deficiency delays renal recovery in mice after ischemia-reperfusion injury by impairing autophagy.
Telomerase dysregulation in the hippocampus of a rat model of depression: normalization by lithium.
Telomerase enzymatic component hTERT shortens long telomeres in human cells.
Telomerase expression confers cardioprotection in the adult mouse heart after acute myocardial infarction.
Telomerase expression in amyotrophic lateral sclerosis (ALS) patients.
Telomerase functions beyond telomere maintenance in primary cutaneous T-cell lymphoma.
Telomerase Gene (hTERT) and Survival: Results From Two Swedish Cohorts of Older Adults.
Telomerase gene mutations and telomere length shortening in patients with idiopathic pulmonary fibrosis in a Chinese population.
Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer
Telomerase gene therapy rescues telomere length, bone marrow aplasia, and survival in mice with aplastic anemia.
Telomerase induction in T cells: A cure for aging and disease?
Telomerase inhibition abolishes the tumorigenicity of pediatric ependymoma tumor-initiating cells.
Telomerase inhibition decreases alpha-fetoprotein expression and secretion by hepatocellular carcinoma cell lines: in vitro and in vivo study.
Telomerase inhibitor Imetelstat (GRN163L) limits the lifespan of human pancreatic cancer cells.
Telomerase is not an oncogene
Telomerase is Not an Oncogene
Telomerase lost?
Telomerase mutations in smokers with severe emphysema
Telomerase mutations in smokers with severe emphysema.
Telomerase promoter mutations in cancer: an emerging molecular biomarker?
Telomerase protects werner syndrome lineage-specific stem cells from premature aging.
Telomerase redux: ready for prime time?
Telomerase regulates MYC-driven oncogenesis independent of its reverse transcriptase activity.
Telomerase Reverse Transcriptase (TERT) Gene Variations and Susceptibility of Colorectal Cancer.
Telomerase Reverse Transcriptase and Peroxisome Proliferator-Activated Receptor γ Co-Activator-1α Cooperate to Protect Cells from DNA Damage and Mitochondrial Dysfunction in Vascular Senescence.
Telomerase Reverse Transcriptase Delays Aging in Cancer-Resistant Mice
Telomerase Reverse Transcriptase Delays Aging in Cancer-Resistant Mice
Telomerase reverse transcriptase expression protects transformed human cells against DNA-damaging agents, and increases tolerance to chromosomal instability.
Telomerase reverse transcriptase has an extratelomeric function in somatic cell reprogramming.
Telomerase reverse transcriptase in the regulation of gene expression.
Telomerase reverse transcriptase moonlights: Therapeutic targets beyond telomerase.
Telomerase reverses epidermal hair follicle stem cell defects and loss of long-term survival associated with critically short telomeres
Telomerase reverses epidermal hair follicle stem cell defects and loss of long-term survival associated with critically short telomeres
Telomerase RNA stem terminus element affects template boundary element function, telomere sequence, and shelterin binding.
Telomerase RNA TLC1 shuttling to the cytoplasm requires mRNA export factors and is important for telomere maintenance.
Telomerase structure.
Telomerase Therapeutics for Degenerative Diseases
Telomerase variant A279T induces telomere dysfunction and inhibits non-canonical telomerase activity in esophageal carcinomas.
Telomerase-based approaches to enhance immunity to viruses during ageing
Telomerase-based approaches to enhance immunity to viruses during ageing
Telomerase-Based Pharmacologic Enhancement of Antiviral Function of Human CD8+ T Lymphocytes1
Telomerase-dependent and independent telomere maintenance and its clinical implications in medullary thyroid carcinoma.
Telomerase-mediated telomere elongation from human blastocysts to embryonic stem cells.
Telomerase, hTERT and splice variants in patients with myelodysplastic syndromes.
Telomere 1 (POT1) gene expression and its association with telomerase activity in colorectal tumor samples with different pathological features.
Telomere analysis to predict chronic lymphocytic leukemia outcome: a STELA test to change clinical practice?
Telomere and adaptive immunity
Telomere and telomerase biology.
Telomere and telomerase in chronic liver disease and hepatocarcinoma.
Telomere and telomerase in stem cells
TELOMERE AND TELOMERASE MODULATION BY BERGAMOT POLYPHENOLIC FRACTION IN EXPERIMENTAL PHOTOAGEING IN HUMAN KERATINOCYTES.
Telomere and telomerase stability in human diseases and cancer.
Telomere Athenaeum
Telomere Athenaeum
Telomere Athenaeum for A4M Members
Telomere attrition and candidate gene mutations preceding monosomy 7 in aplastic anemia.
Telomere attrition and restoration in the normal teleost Oryzias latipes are linked to growth rate and telomerase activity at each life stage.
Telomere Attrition in Human Lens Epithelial Cells Associated with Oxidative Stress Provide a New Therapeutic Target for the Treatment, Dissolving and Prevention of Cataract with N-Acetylcarnosine Lubricant Eye Drops. Kinetic, Pharmacological and Activity-
Telomere biology in stem cells and reprogramming.
Telomere biology: Rationale for diagnostics and therapeutics in cancer.
Telomere Chromatin Condensation Assay (TCCA): a novel approach to study structural telomere integrity.
Telomere content and risk of second malignant neoplasm in survivors of childhood cancer: a report from the Childhood Cancer Survivor Study.
Telomere distribution pattern and synapsis initiation during spermatogenesis in zebrafish.
Telomere dynamics and aging.
Telomere dynamics during aging in polygenic left ventricular hypertrophy.
Telomere dynamics in parasitic great spotted cuckoos and their magpie hosts.
Telomere dynamics in patients with del (5q) MDS before and under treatment with lenalidomide.
Telomere dynamics in the lower plant Physcomitrella patens.
Telomere dynamics in wild brown trout: effects of compensatory growth and early growth investment.
Telomere dynamics may link stress exposure and ageing across generations.
Telomere dysfunction accurately predicts clinical outcome in chronic lymphocytic leukaemia, even in patients with early stage disease.
Telomere Dysfunction and Cell Senescence in Chronic Lung Diseases: Therapeutic Potential.
Telomere dysfunction and chromothripsis.
Telomere dysfunction and hematologic disorders.
Telomere dysfunction causes alveolar stem cell failure.
Telomere dysfunction drives aberrant hematopoietic differentiation and myelodysplastic syndrome
Telomere dysfunction drives aberrant hematopoietic differentiation and myelodysplastic syndrome.
Telomere dysfunction in hypertension
Telomere dysfunction in peripheral blood lymphocytes from patients with primary sclerosing cholangitis and inflammatory bowel disease.
Telomere dysfunction in peripheral blood mononuclear cells from patients with primary biliary cirrhosis.
Telomere dysfunction reduces microglial numbers without fully inducing an aging phenotype.
Telomere dysfunction suppresses multiple endocrine neoplasia in mice.
Telomere Dysfunction-Induced DNA Damage Drives Myelodysplastic Syndrome.
Telomere Dysfunction, Chromosomal Instability and Cancer.
Telomere Dysfunction: A Potential Cancer Predisposition Factor
Telomere elongation and naive pluripotent stem cells achieved from telomerase haplo-insufficient cells by somatic cell nuclear transfer.
Telomere elongation chooses TERRA ALTernatives.
Telomere elongation facilitated by trichostatin a in cloned embryos and pigs by somatic cell nuclear transfer.
Telomere elongation in parthenogenetic stem cells.
Telomere extension by telomerase and ALT generates variant repeats by mechanistically distinct processes.
Telomere Fragment Induced Amnion Cell Senescence: A Contributor to Parturition?
Telomere functions grounding on TERRA firma.
Telomere fusion threshold identifies a poor prognostic subset of breast cancer patients.
Telomere G-Quadruplex as a Potential Target to Accelerate Telomere Shortening by Expanding the Incomplete End-Replication of Telomere DNA.
Telomere G-tail Length is a Promising Biomarker Related to White Matter Lesions and Endothelial Dysfunction in Patients With Cardiovascular Risk: A Cross-sectional Study.
Telomere homeostasis in mammalian germ cells: a review.
Telomere homeostasis in trophoblasts and in cord blood cells from pregnancies complicated with preeclampsia.
Telomere homeostasis is compromised in spermatocytes from patients with idiopathic infertility.
Telomere instability in papillary bladder urothelial carcinomas: Comparison with grading and risk of recurrence.
telomere length
Telomere length - a cellular aging marker for depression and Post-traumatic Stress Disorder.
Telomere length abnormalities and telomerase RNA component expression in gastroenteropancreatic neuroendocrine tumors.
Telomere length alterations unique to invasive lobular carcinoma.
Telomere length analysis and preterm infant health: the importance of assay design in the search for novel biomarkers.
Telomere length analysis in Cushing's syndrome.
Telomere length and age-at-menopause in the US.
Telomere length and aneuploidy: clinical and biological insights into human preimplantation embryos.
Telomere length and common disease: study design and analytical challenges.
Telomere length and cortisol reactivity in children of depressed mothers.
Telomere length and hypothalamic-pituitary-adrenal axis response to stress in elderly adults.
Telomere length and mortality following a diagnosis of ovarian cancer.
Telomere Length and Mortality: A Study of Leukocytes in Elderly Danish Twins
Telomere Length and Mortality: A Study of Leukocytes in Elderly Danish Twins
Telomere length and outcomes in ischaemic heart failure: data from the COntrolled ROsuvastatin multiNAtional Trial in Heart Failure (CORONA).
Telomere length and Parkinson's disease in men: a nested case-control study.
Telomere length and periodontal attachment loss: a prospective cohort study.
Telomere length and polyunsaturated fatty acids.
Telomere length and recurrence risk after curative resection in patients with early-stage non-small-cell lung cancer: a prospective cohort study.
Telomere length and replicative aging in human vascular tissues
Telomere Length and Risk of Incident Cancer and Cancer Mortality
Telomere length and survival in IPF patients - Reply.
Telomere length and survival in IPF patients.
Telomere length and telomerase activity during oocyte maturation and early embryo development in mammalian species.
Telomere length and telomerase activity in bovine pre-implantation embryos in vitro.
Telomere length and telomerase activity in non-small cell lung cancer prognosis: clinical usefulness of a specific telomere status.
Telomere length and telomerase expression in pituitary tumors.
Telomere length and telomerase in a well-characterized sample of individuals with major depressive disorder compared to controls.
Telomere length and telomere repeating factors: Cellular markers for post-traumatic stress disorder-like model.
Telomere length and the clinical phenotype of frailty in older adults undergoing cardiac surgery.
Telomere length and the risk of atrial fibrillation: insights into the role of biological versus chronological aging.
Telomere length and the risk of cutaneous melanoma and non-melanoma skin cancer: a review of the literature and meta-analysis.
Telomere length as a biomarker for adiposity changes after a multidisciplinary intervention in overweight/obese adolescents: the EVASYON study.
Telomere length as a marker of cellular aging is associated with prevalence and progression of metabolic syndrome.
Telomere length as a marker of sleep loss and sleep disturbances: a potential link between sleep and cellular senescence.
Telomere length as a predictor of response to Pioglitazone in patients with unremitted depression: a preliminary study.
Telomere Length as a Prognostic Factor for Overall Survival in Colorectal Cancer Patients.
Telomere length as a risk factor for hereditary prostate cancer.
Telomere length at diagnosis of chronic phase chronic myeloid leukemia (CML-CP) identifies a subgroup with favourable prognostic parameters and molecular response according to the ELN criteria after 12 months of treatment with nilotinib.
Telomere length attrition and chronic periodontitis: an ARIC Study nested case-control study.
Telomere length differences between subcutaneous and visceral adipose tissue in humans.
Telomere length in bipolar disorder and lithium response.
Telomere length in blood cells is related to the chronicity, severity, and recurrence rate of schizophrenia.
Telomere length in Chernobyl accident recovery workers in the late period after the disaster.
Telomere length in children environmentally exposed to low-to-moderate levels of lead.
Telomere length in circulating leukocytes is associated with lung function and disease.
Telomere length in circulating lymphocytes: Association with chromosomal aberrations.
Telomere Length in Different Tissues of Elderly Patients
Telomere length in early childhood: Early life risk factors and association with carotid intima-media thickness in later childhood.
Telomere length in hematopoietic stem cell transplantation for severe aplastic anemia: is it ready for "prime time"?
Telomere length in human blastocysts.
Telomere length in human natural killer cell subsets
Telomere length in inherited bone marrow failure syndromes.
Telomere length in interstitial lung diseases.
Telomere length in non-neoplastic colonic mucosa in ulcerative colitis (UC) and its relationship to the severe clinical phenotypes.
Telomere length in non-neoplastic gastric mucosa and its relationship to H. pylori infection, degree of gastritis, and NSAID use.
Telomere length in Parkinson's disease: A meta-analysis.
Telomere length in peripheral blood leukocytes and lung cancer risk: a large case-control study in Caucasians.
Telomere length in peripheral blood leukocytes is associated with risk of colorectal cancer in Chinese population.
Telomere Length in Peripheral Blood Leukocytes Is Associated with Severity of Biliary Atresia.
Telomere Length in Peripheral Blood Mononuclear Cells of Patients on Chronic Hemodialysis Is Related With Telomerase Activity and Treatment Duration.
Telomere length in peripheral leukocytes is associated with immune cell tumor infiltration and prognosis in colorectal cancer patients.
Telomere length in the two extremes of abnormal fetal growth and the programming effect of maternal arterial hypertension.
Telomere length in white blood cell DNA and lung cancer: a pooled analysis of three prospective cohorts.
Telomere length increase after weight loss induced by bariatric surgery: results from a 10 years prospective study.
Telomere length is a novel predictive biomarker of sensitivity to anti-EGFR therapy in metastatic colorectal cancer.
Telomere length is a prognostic biomarker in elderly advanced ovarian cancer patients: a multicenter GINECO study.
Telomere length is associated with decline in grip strength in older persons aged 65 years and over.
Telomere length is associated with oppositional defiant behavior and maternal clinical depression in Latino preschool children.
Telomere length is associated with sleep duration but not sleep quality in adults with human immunodeficiency virus.
Telomere length is highly inherited and associated with hyperactivity-impulsivity in children with attention deficit/hyperactivity disorder.
Telomere length is inversely correlated with urinary stress hormone levels in healthy controls but not in un-medicated depressed individuals - Preliminary findings.
Telomere length is not associated with frailty in older Chinese elderly: Cross-sectional and longitudinal analysis.
Telomere Length Is Not Related to Established Cardiovascular Risk Factors but Does Correlate with Red and White Blood Cell Counts in a German Blood Donor Population.
Telomere length is paternally inherited and is associated with parental lifespan
Telomere length kinetics assay (TELKA) sorts the telomere length maintenance (tlm) mutants into functional groups.
Telomere length linked to emphysema risk
Telomere length loss due to smoking and metabolic traits.
Telomere Length Maintenance and Cardio-Metabolic Disease Prevention Through Exercise Training.
Telomere length maintenance, shortening, and lengthening.
Telomere length measurement on the Roche LightCycler 480 Platform.
Telomere Length Measurements in Leukocyte Subsets by Automated Multicolor Flow-FISH
Telomere Length of Human Adult Bronchial Epithelium and Bronchogenic Squamous Cell Carcinoma Measured Using Tissue Quantitative Fluorescence in situ Hybridization.
Telomere length of recipients and living kidney donors and chronic graft dysfunction in kidney transplants.
Telomere length of tumor tissues and survival in patients with early stage non-small cell lung cancer.
Telomere length predicts cardiovascular disease.
Telomere length predicts progression and overall survival in chronic lymphocytic leukemia: data from the UK LRF CLL4 trial.
Telomere length predicts survival independent of genetic influences
Telomere length regulation in budding yeasts.
Telomere length reprogramming in embryos and stem cells.
Telomere Length Shortening and Alzheimer Disease--A Mendelian Randomization Study.
Telomere length shows no association with BRCA1 and BRCA2 mutation status.
Telomere Length Trajectory and Its Determinants in Persons with Coronary Artery Disease: Longitudinal Findings from the Heart and Soul Study
Telomere length variability is related to symptoms and cognition in schizophrenia.
Telomere length variation: A potential new telomere biomarker for lung cancer risk.
Telomere length variations in aging and age-related diseases.
Telomere length varies by DNA extraction method: implications for epidemiologic research--response.
Telomere length varies by DNA extraction method: implications for epidemiologic research-letter.
Telomere length, cardiovascular risk and arteriosclerosis in human kidneys: an observational cohort study.
Telomere length, cardiovascular risk and arteriosclerosis in human kidneys: an observational cohort study.
Telomere length, family history, and paternal age in schizophrenia.
Telomere length, genetic variants and gastric cancer risk in a Chinese population.
Telomere length, genetic variants and risk of squamous cell carcinoma of the head and neck in Southeast Chinese.
Telomere length, stem cells and aging
Telomere length, stem cells and aging
Telomere length, telomerase expression, and oxidative stress in lead smelters.
Telomere length: a review of methods for measurement.
Telomere lengthening after three weeks of an intensive insight meditation retreat.
Telomere lengths at birth in trisomies 18 and 21 measured by Q-FISH.
Telomere longitudinal shortening as a biomarker for dementia status of adults with Down syndrome.
Telomere maintenance and the etiology of adult glioma.
Telomere maintenance as a target for drug discovery.
Telomere Maintenance Is a Critical Determinant in the Physiopathology of Pulmonary Hypertension.
Telomere maintenance mechanisms in cancer: clinical implications.
Telomere maintenance through recruitment of internal genomic regions.
Telomere mean length in patients with diabetic retinopathy.
Telomere measurement by quantitative PCR
Telomere measurement in individuals occupationally exposed to pesticide mixtures in tobacco fields.
Telomere position effect: regulation of gene expression with progressive telomere shortening over long distances.
Telomere profiles and tumor-associated macrophages with different immune signatures affect prognosis in glioblastoma.
Telomere protein Rap1 is a charge resistant scaffolding protein in chromosomal bouquet formation.
Telomere Q-PNA-FISH--reliable results from stochastic signals.
Telomere recombination and the ALT pathway: a therapeutic perspective for cancer.
Telomere recombination preferentially occurs at short telomeres in telomerase-null type II survivors.
Telomere regulation during ageing and tumorigenesis of the grey mouse lemur.
Telomere regulation during the cell cycle in fission yeast.
Telomere regulation in pluripotent stem cells.
Telomere repeat binding proteins are functional components of Arabidopsis telomeres and interact with telomerase.
Telomere Repeat-Binding Factor 2 Is Responsible for the Telomere Attachment to the Nuclear Membrane.
Telomere repeats and macronuclear DNA organization in the soil ciliate Kahliella matisi (Ciliophora, Hypotricha).
Telomere reverse transcriptase (TERT) rs2735940 increases cancer risk.
Telomere Science Library Resources
Telomere Science Podcasts
Telomere Science Presentations
Telomere Science Videos
Telomere shortening and aging
Telomere shortening and aging
Telomere shortening and Alzheimer's disease.
Telomere shortening and immune activity in war veterans with posttraumatic stress disorder.
Telomere shortening and increased oxidative stress are restricted to venous tissue in patients with varicose veins: A merely local disease?
Telomere shortening and telomerase activity in ischaemic cardiomyopathy patients - Potential markers of ventricular arrhythmia.
Telomere shortening and telomere position effect in mild ring 17 syndrome.
Telomere shortening as genetic risk factor of liver cirrhosis.
Telomere shortening associated with increased genomic complexity in chronic lymphocytic leukemia.
Telomere shortening correlates to dysplasia but not to DNA aneuploidy in longstanding ulcerative colitis.
Telomere shortening correlates with accelerated replicative senescence of bronchial fibroblasts in asthma.
Telomere Shortening in Blood Leukocytes of Patients with Chronic Obstructive Pulmonary Disease.
Telomere shortening in breast cancer correlates with the pathological features of tumor progression.
Telomere shortening in Down syndrome patients--when does it start?
Telomere shortening in elderly individuals with mild cognitive impairment may be attenuated with ω-3 fatty acid supplementation: a randomized controlled pilot study.
Telomere shortening in enterocytes of patients with uncontrolled acute intestinal graft-versus-host disease.
Telomere shortening in intra uterine growth restriction placentas.
Telomere shortening in leukocyte subpopulations in depression.
Telomere shortening in mucosa surrounding the tumor: biosensor of field cancerization and prognostic marker of mucosal failure in head and neck squamous cell carcinoma.
Telomere shortening in neurological disorders: an abundance of unanswered questions.
Telomere shortening in sleep apnea syndrome
Telomere shortening in the colonial coral Acropora digitifera during development.
Telomere shortening is associated with genetic anticipation in Chinese Von Hippel-Lindau disease families.
Telomere shortening over 6 years is associated with increased subclinical carotid vascular damage and worse cardiovascular prognosis in the general population.
Telomere shortening unrelated to smoking, body weight, physical activity, and alcohol intake: 4,576 general population individuals with repeat measurements 10 years apart.
Telomere shortening: a biological marker of sporadic colorectal cancer with normal expression of p53 and mismatch repair proteins.
Telomere shortening: a diagnostic tool and therapeutic target for cardiovascular disease?
Telomere shortening: a new prognostic factor for cardiovascular disease post-radiation exposure.
Telomere stability and development of ctc1 mutants are rescued by inhibition of EJ recombination pathways in a telomerase-dependent manner.
Telomere targeting with a novel G-quadruplex-interactive ligand BRACO-19 induces T-loop disassembly and telomerase displacement in human glioblastoma cells.
Telomere-associated factor expression in replicative senescence of human embryonic lung fibroblasts.
Telomere-associated proteins add deoxynucleotides to terminal proteins during replication of the telomeres of linear chromosomes and plasmids in Streptomyces.
Telomere-binding protein regulates the chromosome ends through the interaction with histone deacetylases in Arabidopsis thaliana.
Telomere-centric genome repatterning determines recurring chromosome number reductions during the evolution of eukaryotes.
Telomere-dependent genomic integrity: evolution of the fusion-bridge-breakage cycle concept.
Telomere-dependent senescent phenotype of lens epithelial cells as a biological marker of aging and cataractogenesis
Telomere-independent ageing in the longest-lived non-colonial animal, Arctica islandica.
Telomere-independent functions of telomerase in nuclei, cytoplasm, and mitochondria
Telomere-length dependent T-cell clonal expansion: A model linking ageing to COVID-19 T-cell lymphopenia and mortality
Telomere-mediated chromosomal truncation in Aspergillus oryzae.
Telomere-regulating genes and the telomere interactome in familial cancers.
Telomeres and centromeres have interchangeable roles in promoting meiotic spindle formation.
Telomeres and diseases.
Telomeres and essential hypertension.
Telomeres and Female Reproductive Aging.
Telomeres and telomerase in T cells of tumor immunity.
Telomeres and Telomerase in the Radiation Response: Implications for Instability, Reprograming, and Carcinogenesis.
Telomeres and telomerase: understanding basic structure and potential new therapeutic strategies targeting it in the treatment of cancer.
Telomeres and their role in aging and longevity.
Telomeres are elongated in rats exposed to moderate altitude.
Telomeres are partly shielded from ultraviolet-induced damage and proficient for nucleotide excision repair of photoproducts.
Telomeres are shorter in placentas from pregnancies with uncontrolled diabetes.
Telomeres as Therapeutic Targets in Heart Disease
Telomeres in Disease
Telomeres in lung diseases.
Telomeres in molecular epidemiology studies.
Telomeres open a window on stem cell division.
Telomeres shorten in response to oxidative stress in mouse skeletal muscle fibers.
Telomeres shorten more slowly in slow-aging wild animals than in fast-aging ones.
Telomeres Tell Future in Aplastic Anemia
Telomeres, atherosclerosis, and human longevity: a causal hypothesis.
Telomeres, cardiovascular aging, and potential intervention for cellular senescence.
Telomeres, early-life stress and mental illness.
Telomeres, telomerase and colorectal cancer.
Telomeres: Cancer to Human Aging
Telomeres: Cancer to Human Aging
Telomeric 1p36.3 deletion and Ki-67 expression in B-Non-Hodgkin's Lymphoma patients associated with chronic hepatitis C virus infection.
Telomeric aging: mitotic clock or stress indicator?
Telomeric attrition with age and temperature in Eastern mosquitofish (Gambusia holbrooki).
Telomeric DNA length in cerebral gray and white matter is associated with longevity in individuals aged 70 years or older
Telomeric G-quadruplex architecture and interactions with potential drugs.
Telomeric G-quadruplex-forming DNA fragments induce TLR9-mediated and LL-37-regulated invasion in breast cancer cells in vitro.
Telomeric g-tail length and hospitalization for cardiovascular events in hemodialysis patients.
Telomeric noncoding RNA: telomeric repeat-containing RNA in telomere biology.
Telomeric ORFs (TLOs) in Candida spp. Encode mediator subunits that regulate distinct virulence traits.
Telomeric ORFS in Candida albicans: does mediator tail wag the yeast?
Telomeric overhang length determines structural dynamics and accessibility to telomerase and ALT-associated proteins.
Telomeric Repeat Containing RNA (TERRA): Aging and Cancer.
Telomeric repeat silencing in germ cells is essential for early development in Drosophila.
Telomeric repeat-containing RNA (TERRA) and telomerase are components of telomeres during mammalian gametogenesis.
Telomeric repeat-containing RNA (TERRA) constitutes a nucleoprotein component of extracellular inflammatory exosomes.
Telomeric repeat-containing RNA TERRA: a noncoding RNA connecting telomere biology to genome integrity.
Telomeric repeat-containing RNA/G-quadruplex-forming sequences cause genome-wide alteration of gene expression in human cancer cells in vivo.
Telomeric repeats act as nucleosome-disfavouring sequences in vivo.
Telomeric transcriptome from Chironomus riparius (Diptera), a species with noncanonical telomeres.
Telomeric transcripts stimulate telomere recombination to suppress senescence in cells lacking telomerase.
Telomeropathies: an emerging spectrum of disorder with important implications for patients with interstitial lung disease.
TeloPIN: a database of telomeric proteins interaction network in mammalian cells.
TeloTool: a new tool for telomere length measurement from terminal restriction fragment analysis with improved probe intensity correction.
TERF1 and TERF2 downregulate telomere length in cognitive deficit at the late period after low-dose exposure.
Terminal 18q deletions are stabilized by neotelomeres.
TERRA and the state of the telomere.
TERRA mimicking ssRNAs prevail over the DNA substrate for telomerase in vitro due to interactions with the alternative binding site.
TERRA-reinforced association of LSD1 with MRE11 promotes processing of uncapped telomeres.
TERT Polymorphism rs2736100-C Is Associated with EGFR Mutation-Positive Non-Small Cell Lung Cancer.
TERT Polymorphism rs2853669 Influences on Lung Cancer Risk in the Korean Population.
TERT polymorphisms rs2853669 and rs7726159 influence on prostate cancer risk in Russian population.
TERT promoter hotspot mutations are recurrent in myxoid liposarcomas but rare in other soft tissue sarcoma entities.
TERT promoter mutation as an early genetic event activating telomerase in follicular thyroid adenoma (FTA) and atypical FTA.
TERT promoter mutations and long telomere length predict poor survival and radiotherapy resistance in gliomas.
TERT promoter mutations and telomere length in adult malignant gliomas and recurrences.
TERT promoter mutations are a rare event in gastrointestinal stromal tumors.
TERT promoter mutations are frequent and show association with MED12 mutations in phyllodes tumors of the breast.
TERT promoter mutations are frequent in atypical fibroxanthomas and pleomorphic dermal sarcomas.
TERT promoter mutations in clear cell renal cell carcinoma.
TERT promoter mutations in primary liver tumors.
Testosterone Antagonizes Doxorubicin-Induced Senescence of Cardiomyocytes.
Tetrahymena Pot2 is a developmentally regulated paralog of Pot1 that localizes to chromosome breakage sites but not to telomeres.
The 3' overhangs at Tetrahymena thermophila telomeres are packaged by four proteins, Pot1a, Tpt1, Pat1, and Pat2.
The 68-kDa telomeric repeat binding factor 1 (TRF1)-associated protein (TAP68) interacts with and recruits TRF1 to the spindle pole during mitosis.
The 9-1-1 checkpoint clamp coordinates resection at DNA double strand breaks.
The 9-1-1 checkpoint clamp stimulates DNA resection by Dna2-Sgs1 and Exo1.
The activating TERT promoter mutation C228T is recurrent in subsets of adrenal tumors.
The age- and shorter telomere-dependent TERT promoter mutation in follicular thyroid cell-derived carcinomas.
The antiaging activity and cerebral protection of rapamycin at micro-doses.
The Arabidopsis thaliana homolog of the helicase RTEL1 plays multiple roles in preserving genome stability.
The architecture and evolution of cancer neochromosomes.
The ARPE-19 cell line: mortality status and utility in macular degeneration research.
The assessment of CD146-based cell sorting and telomere length analysis for establishing the identity of mesenchymal stem cells in human umbilical cord.
The association between depression and leukocyte telomere length: a meta-analysis.
The association between global DNA methylation and telomere length in a longitudinal study of boilermakers.
The association between leukocyte telomere length and cigarette smoking, dietary and physical variables, and risk of prostate cancer
The association between leukocyte telomere length and cigarette smoking, dietary and physical variables, and risk of prostate cancer
The association between leukocyte telomere length and mitochondrial DNA copy number in pregnant women: a pilot study.
The association between leukocyte telomere lengths and sleep instability based on cardiopulmonary coupling analysis.
The Association Between Physical Activity in Leisure Time and Leukocyte Telomere Length
The Association between Telomere Length and Cancer Prognosis: Evidence from a Meta-Analysis.
The association between telomere length and cancer risk in population studies.
The Association of Early and Recent Psychosocial Life Stress With Leukocyte Telomere Length.
The association of telomere length with colorectal cancer differs by the age of cancer onset.
The association of telomere length with family violence and disruption.
The asymmetry of telomere replication contributes to replicative senescence heterogeneity.
The Axis Of Aging
The basic N-terminal domain of TRF2 limits recombination endonuclease action at human telomeres.
The biliary epithelium gives rise to liver progenitor cells.
The biology of satellite cells and telomeres in human skeletal muscle: effects of aging and physical activity
The C-terminal extension of human RTEL1, mutated in Hoyeraal-Hreidarsson syndrome, contains harmonin-N-like domains.
The C3G/Rap1 pathway promotes secretion of MMP-2 and MMP-9 and is involved in serous ovarian cancer metastasis.
The CDC13-STN1-TEN1 complex stimulates Pol α activity by promoting RNA priming and primase-to-polymerase switch.
The Cell Adhesion Molecule Necl-4/CADM4 Serves as a Novel Regulator for Contact Inhibition of Cell Movement and Proliferation.
The changes of leukocyte telomere length and telomerase activity after sitagliptin intervention in newly diagnosed type 2 diabetes.
The changing landscape of idiopathic pulmonary fibrosis.
The child is father of the man, and mother of the woman.
The Chromatin and Transcriptional Landscape of Native Saccharomyces cerevisiae Telomeres and Subtelomeric Domains.
The circadian rhythm controls telomeres and telomerase activity.
The co-expression of telomerase and ALT pathway in human breast cancer tissues.
The complex role of SIRT6 in carcinogenesis.
The correlation between peripheral leukocyte telomere length and indicators of cardiovascular aging.
The correlation between telomerase activity and Bax/Bcl-2 ratio in valproic acid-treated MCF-7 breast cancer cell line.
The Ctf18RFC clamp loader is essential for telomere stability in telomerase-negative and mre11 mutant alleles.
The cutting edges in DNA repair, licensing, and fidelity: DNA and RNA repair nucleases sculpt DNA to measure twice, cut once.
The Daxx/Atrx Complex Protects Tandem Repetitive Elements during DNA Hypomethylation by Promoting H3K9 Trimethylation.
The detox strategy in smoking comprising nutraceutical formulas of non-hydrolyzed carnosine or carcinine used to protect human health.
The development of lasting impairments: a mild pediatric brain injury alters gene expression, dendritic morphology, and synaptic connectivity in the prefrontal cortex of rats.
The diagnosis and treatment of dyskeratosis congenita: a review.
The diet as a cause of human prostate cancer.
The differential processing of telomeres in response to increased telomeric transcription and RNA-DNA hybrid accumulation.
The dissection of meiotic chromosome movement in mice using an in vivo electroporation technique.
The diversity of karyotypes and genomes within section Syllinum of the Genus Linum (Linaceae) revealed by molecular cytogenetic markers and RAPD analysis.
The DNA methylation inhibitor induces telomere dysfunction and apoptosis of leukemia cells that is attenuated by telomerase over-expression.
The DNA structure and sequence preferences of WRN underlie its function in telomeric recombination events.
The DNA-binding domain of yeast Rap1 interacts with double-stranded DNA in multiple binding modes.
The draft assembly of the radically organized Stylonychia lemnae macronuclear genome.
The effect of chemotherapeutic agents on telomere length maintenance in breast cancer cell lines.
The Effect of Polymorphisms in DNA Repair Genes and Carcinogen Metabolizers on Leukocyte Telomere Length: A Cohort of Healthy Spanish Smokers.
The effect on melanoma risk of genes previously associated with telomere length.
The effects of chemotherapy with bleomycin, etoposide, and cis-platinum on telomeres in rat male germ cells.
The effects of erythropoietin signaling on telomerase regulation in non-erythroid malignant and non-malignant cells.
The effects of telomere shortening on cancer cells: a network model of proteomic and microRNA analysis.
The enzymes of human diphosphoinositol polyphosphate metabolism.
The ERCC1 and ERCC4 (XPF) genes and gene products.
The FEN1 E359K germline mutation disrupts the FEN1-WRN interaction and FEN1 GEN activity, causing aneuploidy-associated cancers.
The final countdown.
The First Documented Age Reversal in a Mammal: Harvard University Study shows Telomerase Activation Helps Reverse the Aging Process
The Fun30 chromatin remodeler Fft3 controls nuclear organization and chromatin structure of insulators and subtelomeres in fission yeast.
The functional polymorphism rs73598374:G>A (p.Asp8Asn) of the ADA gene is associated with telomerase activity and leukocyte telomere length.
The G-quadruplex-stabilising agent RHPS4 induces telomeric dysfunction and enhances radiosensitivity in glioblastoma cells.
The genetic basis of idiopathic pulmonary fibrosis.
The genomic landscape of mantle cell lymphoma is related to the epigenetically determined chromatin state of normal B cells.
The GG genotype of telomerase reverse transcriptase at genetic locus rs2736100 is associated with human atherosclerosis risk in the Han Chinese population.
The heritability of leucocyte telomere length dynamics.
The histone demethylase activity of Rph1 is not essential for its role in the transcriptional response to nutrient signaling.
The history of sleep apnea is associated with shorter leukocyte telomere length: the Helsinki Birth Cohort Study.
The Hmr and Lhr hybrid incompatibility genes suppress a broad range of heterochromatic repeats.
The hnRNP A1 homolog Hrb87F/Hrp36 is important for telomere maintenance in Drosophila melanogaster.
The HSP90 inhibitor alvespimycin enhances the potency of telomerase inhibition by imetelstat in human osteosarcoma.
The human telomere sequence, (TTAGGG)4, in the absence and presence of cosolutes: a spectroscopic investigation.
The identification of two regulatory ESCC susceptibility genetic variants in the TERT-CLPTM1L loci.
The Impact of Age and Sex in DLBCL: Systems Biology Analyses Identify Distinct Molecular Changes and Signaling Networks.
The impact of early nutrition on the ageing trajectory.
The Impact of Immunosenescence on Pulmonary Disease.
The importance of early life studies of telomere attrition.
The impracticality of biomedical rejuvenation therapies: translational and pharmacological barriers.
The Influence of Alcohol Consumption, Cigarette Smoking, and Physical Activity on Leukocyte Telomere Length.
The Influence of Energetic Factors on Biomarkers of Postmenopausal Breast Cancer Risk.
The influence of oxidative stress induced by iron on telomere length.
The influence of the telomere-telomerase system on diabetes mellitus and its vascular complications.
The inhibitory effect of helenalin on telomerase activity is attributed to the alkylation of the CYS445 residue: evidence from QM/MM simulations.
The Insertion in Fingers Domain in Human Telomerase Can Mediate Enzyme Processivity and Telomerase Recruitment to Telomeres in a TPP1-Dependent Manner.
The interaction between stressful life events and leukocyte telomere length is associated with PTSD.
The Ku heterodimer: function in DNA repair and beyond.
The Ku subunit of telomerase binds Sir4 to recruit telomerase to lengthen telomeres in S. cerevisiae.
The landscape of transposable elements in the finished genome of the fungal wheat pathogen Mycosphaerella graminicola.
The leukemia-associated Rho guanine nucleotide exchange factor LARG is required for efficient replication stress signaling.
The lighthouse at the end of the chromosome.
The load of short telomeres is increased and associated with lifetime number of depressive episodes in bipolar II disorder
The Long and Short of It: The Role of Telomeres in Fetal Origins of Adult Disease
The long and short of telomere length and diabetes.
The long reach of telomeres.
The long-term impact of adverse caregiving environments on epigenetic modifications and telomeres.
The master switchers in the aging of cardiovascular system, reverse senescence by microRNA signatures; as highly conserved molecules.
The mating type-like loci of Candida glabrata.
The methylating agent streptozotocin induces persistent telomere dysfunction in mammalian cells.
The missing LINC: a mammalian KASH-domain protein coupling meiotic chromosomes to the cytoskeleton.
The mitochondrial lncRNA ASncmtRNA-2 is induced in aging and replicative senescence in Endothelial Cells.
The MNS16A polymorphism in the TERT gene in peri-centenarians from the Han Chinese population.
The Molecular Genetics of the Telomere Biology Disorders.
The molecular mechanism of ligand unbinding from the human telomeric G-quadruplex by steered molecular dynamics and umbrella sampling simulations.
The Molecular Signature of HIV-1-Associated Lipomatosis Reveals Differential Involvement of Brown and Beige/Brite Adipocyte Cell Lineages.
The molecular topography of silenced chromatin in Saccharomyces cerevisiae.
The mTOR pathway is necessary for survival of mice with short telomeres
The N-terminal domain of human DNA helicase Rtel1 contains a redox active iron-sulfur cluster.
The N-terminus and Tudor domains of Sgf29 are important for its heterochromatin boundary formation function.
The NEIL glycosylases remove oxidized guanine lesions from telomeric and promoter quadruplex DNA structures.
The non-reverse transcriptase activity of the human telomerase reverse transcriptase promotes tumor progression (review).
The OB-fold domain 1 of human POT1 recognizes both telomeric and non-telomeric DNA motifs.
The onset of heat-induced testicular calcification in mice: involvement of the telomeric locus on chromosome 1.
The paradox of longer sperm telomeres in older men's testes: a birth-cohort effect caused by transgenerational telomere erosion in the female germline.
The physical map of wheat chromosome 5DS revealed gene duplications and small rearrangements.
The Pif1 family helicase Pfh1 facilitates telomere replication and has an RPA-dependent role during telomere lengthening.
The pif1 helicase, a negative regulator of telomerase, acts preferentially at long telomeres.
The PML-associated protein DEK regulates the balance of H3.3 loading on chromatin and is important for telomere integrity.
The presence of telomere fusion in sporadic colon cancer independently of disease stage, TP53/KRAS mutation status, mean telomere length, and telomerase activity.
The principal role of Ku in telomere length maintenance is promotion of Est1 association with telomeres.
The promoter activation at the end of terminally truncated chromosome in Drosophila melanogaster.
The proper splicing of RNAi factors is critical for pericentric heterochromatin assembly in fission yeast.
The putative Leishmania telomerase RNA (LeishTER) undergoes trans-splicing and contains a conserved template sequence.
The radiomimetic compound streptonigrin induces persistent telomere dysfunction in mammalian cells.
The rate of leukocyte telomere shortening predicts mortality from cardiovascular disease in elderly men
The recognition of the role of telomeres in cell biology dates back to the 1930s. Introduction.
The relationship between COPD and lung cancer.
The relationship between inflammatory biomarkers and telomere length in an occupational prospective cohort study.
The Relationship Between Perceived Stress and Telomere Length: A Meta-analysis.
The relationship between telomere length and beekeeping among Malaysians.
The relationship between telomere length and clinicopathologic characteristics in colorectal cancers among Tunisian patients.
The relationship between the nucleolus and cancer: Current evidence and emerging paradigms.
The relationship of telomere length to baseline corticosterone levels in nestlings of an altricial passerine bird in natural populations.
The replicometer is broken: telomeres activate cellular senescence in response to genotoxic stresses.
The role of childhood trauma in bipolar disorders.
The role of double-strand break repair pathways at functional and dysfunctional telomeres.
The role of Exo1p exonuclease in DNA end resection to generate gene conversion tracts in Saccharomyces cerevisiae.
The Role of Genome Instability in Frailty: Mitochondria versus Nucleus.
The role of post-translational modifications in fine-tuning BLM helicase function during DNA repair.
The role of quantitative mass spectrometry in the discovery of pancreatic cancer biomarkers for translational science.
The role of RecQ helicases in non-homologous end-joining.
The role of telomerase protein TERT in Alzheimer's disease and in tau-related pathology in vitro.
The role of telomeres and telomerase in hematologic malignancies and hematopoietic stem cell transplantation.
The Role of Telomeres and Telomerase Reverse Transcriptase Isoforms in Pluripotency Induction and Maintenance.
The role of telomeres and vitamin D in cellular aging and age-related diseases.
The role of telomeres in liver disease.
The role of telomeres in predicting individual radiosensitivity of patients with cancer in the era of personalized radiotherapy.
The role of the TERC-63G>A and TERT-1327C>T telomerase polymorphisms in the study of men with acute coronary syndrome.
The roles of DNA damage-dependent signals and MAPK cascades in tributyltin-induced germline apoptosis in Caenorhabditis elegans.
The SAGA histone deubiquitinase module controls yeast replicative lifespan via Sir2 interaction.
The secreted protein S100A7 (psoriasin) is induced by telomere dysfunction in human keratinocytes independently of a DNA damage response and cell cycle regulators.
The senescent microenvironment promotes the emergence of heterogeneous cancer stem-like cells.
The shelterin component TPP1 is a binding partner and substrate for the deubiquitinating enzyme USP7.
The Shelterin TIN2 Subunit Mediates Recruitment of Telomerase to Telomeres.
The short and long telomere syndromes: paired paradigms for molecular medicine.
The splicing factor U2AF65 stabilizes TRF1 protein by inhibiting its ubiquitin-dependent proteolysis.
The structure and DNA-binding properties of Mgm101 from a yeast with a linear mitochondrial genome.
The structure of Rap1 in complex with RIAM reveals specificity determinants and recruitment mechanism.
The structure, function and evolution of proteins that bind DNA and RNA.
The study on telomere length for age estimation in a Thai population.
The subtelomeric region is important for chromosome recognition and pairing during meiosis.
The tap-tpg gene pair on the linear plasmid functions to maintain a linear topology of the chromosome in Streptomyces rochei.
The telomerase activator TA-65 protects from cigarette smoke-induced small airway remodeling in mice through extra-telomeric effects
The Telomerase Activator, TA-65®, Elongates Short Telomeres and Increases Healthspan of Adult/Old Mice without Increasing Cancer Incidence
The telomerase essential N-terminal domain promotes DNA synthesis by stabilizing short RNA-DNA hybrids.
The telomerase inhibitor imetelstat alone, and in combination with trastuzumab, decreases the cancer stem cell population and self-renewal of HER2+ breast cancer cells.
The telomere bouquet regulates meiotic centromere assembly.
The telomere profile distinguishes two classes of genetically distinct cutaneous squamous cell carcinomas.
The telomere-telomerase axis and the heart
The telomere/telomerase binding factor PinX1 regulates paclitaxel sensitivity depending on spindle assembly checkpoint in human cervical squamous cell carcinomas.
The telomeric protein Pot1 from Schizosaccharomyces pombe binds ssDNA in two modes with differing 3' end availability.
The Telomeric Protein TRF2 Regulates Angiogenesis by Binding and Activating the PDGFRβ Promoter.
The telomeric sync model of speciation: species-wide telomere erosion triggers cycles of transposon-mediated genomic rearrangements, which underlie the saltatory appearance of nonadaptive characters.
The tenacious recognition of yeast telomere sequence by Cdc13 is fully exerted by a single OB-fold domain.
The TERT promoter SNP rs2853669 decreases E2F1 transcription factor binding and increases mortality and recurrence risks in liver cancer.
The theory of bipolar disorder as an illness of accelerated aging: implications for clinical care and research.
The topoisomerase II catalytic inhibitor ICRF-193 preferentially targets telomeres that are capped by TRF2.
The transcription factor Rap1p is required for tolerance to cell-wall perturbing agents and for cell-wall maintenance in Saccharomyces cerevisiae.
The TRF1-binding protein TERB1 promotes chromosome movement and telomere rigidity in meiosis.
The unfolded protein response and cellular senescence. A review in the theme: cellular mechanisms of endoplasmic reticulum stress signaling in health and disease.
The use of telomere length as a predictive biomarker for injury prognosis in juvenile rats following a concussion/mild traumatic brain injury.
The use of transformed IMR90 cell model to identify the potential extra-telomeric effects of hTERT in cell migration and DNA damage response.
The wide-ranging clinical implications of the short telomere syndromes.
The wrapping loop and Rap1 C-terminal (RCT) domain of yeast Rap1 modulate access to different DNA binding modes.
The yeast Cyc8-Tup1 complex cooperates with Hda1p and Rpd3p histone deacetylases to robustly repress transcription of the subtelomeric FLO1 gene.
Therapeutic inhibition of TRF1 impairs the growth of p53-deficient K-RasG12V-induced lung cancer by induction of telomeric DNA damage.
Therapeutic targeting of replicative immortality.
Therapeutics That Can Potentially Replicate or Augment the Anti-Aging Effects of Physical Exercise
Three-dimensional architecture of tandem repeats in chicken interphase nucleus.
Three-dimensional quantitative imaging of telomeres in buccal cells identifies mild, moderate, and severe Alzheimer's disease patients.
Three-dimensional telomere architecture of esophageal squamous cell carcinoma: comparison of tumor and normal epithelial cells.
Three-dimensional telomere dynamics in follicular thyroid cancer.
Thymocytes maintain immune activity through telomere elongation in rats under hypoxic conditions.
Tired telomeres: Poor global sleep quality, perceived stress, and telomere length in immune cell subsets in obese men and women.
Tissue formation and tissue engineering through host cell recruitment or a potential injectable cell-based biocomposite with replicative potential: Molecular mechanisms controlling cellular senescence and the involvement of controlled transient telomerase
Tls1 regulates splicing of shelterin components to control telomeric heterochromatin assembly and telomere length.
TNKS1BP1 functions in DNA double-strand break repair though facilitating DNA-PKcs autophosphorylation dependent on PARP-1.
Tobacco smoke-induced lung fibrosis and emphysema.
Toll-like receptor 9 signaling delays neutrophil apoptosis by increasing transcription of Mcl-1.
Toll-like receptor 9 signaling regulates tissue factor and tissue factor pathway inhibitor expression in human endothelial cells and coagulation in mice.
TopoIIα prevents telomere fragility and formation of ultra thin DNA bridges during mitosis through TRF1-dependent binding to telomeres.
Topoisomerase I plays a critical role in suppressing genome instability at a highly transcribed G-quadruplex-forming sequence.
Topoisomerase II inhibition suppresses the proliferation of telomerase-negative cancers.
Total body irradiation causes long-term mouse BM injury via induction of HSC premature senescence in an Ink4a- and Arf-independent manner.
Toward a molecular classification of colorectal cancer: the role of telomere length.
Toward the design of a catalytic metallodrug: selective cleavage of G-quadruplex telomeric DNA by an anticancer copper-acridine-ATCUN complex.
Towards a molecular classification of colorectal cancer.
Towards a piRNA prediction using multiple kernel fusion and support vector machine.
TPP1 Blocks an ATR-Mediated Resection Mechanism at Telomeres.
Tpz1-Ccq1 and Tpz1-Poz1 interactions within fission yeast shelterin modulate Ccq1 Thr93 phosphorylation and telomerase recruitment.
Tpz1TPP1 SUMOylation reveals evolutionary conservation of SUMO-dependent Stn1 telomere association.
Traffic noise exposure affects telomere length in nestling house sparrows.
Transcription factor genes essential for cell proliferation and replicative lifespan in budding yeast.
Transcription factor Sp1 prevents TRF2(ΔBΔM)-induced premature senescence in human diploid fibroblasts.
Transcription of tandemly repetitive DNA: functional roles.
Transcriptional outcome of telomere signalling.
Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer.
Transgenerational Developmental Programming of Ovarian Reserve.
Transient bursts of Zscan4 expression are accompanied by the rapid derepression of heterochromatin in mouse embryonic stem cells.
Transient delivery of modified mRNA encoding TERT rapidly extends telomeres in human cells.
Transient delivery of modified mRNA encoding TERT rapidly extends telomeres in human cells.
Transient induction of telomerase expression mediates senescence and reduces tumorigenesis in primary fibroblasts
Transposon regulation in Drosophila: piRNA-producing P elements facilitate repression of hybrid dysgenesis by a P element that encodes a repressor polypeptide.
Trastuzumab increases the sensitivity of HER2-amplified human gastric cancer cells to oxaliplatin and cisplatin by affecting the expression of telomere-associated proteins.
Treatment of dyskeratosis congenita-associated pulmonary fibrosis with danazol.
TRF1 and TRF2 binding to telomeres is modulated by nucleosomal organization.
TRF1 and TRF2 differentially modulate Rad51-mediated telomeric and nontelomeric displacement loop formation in vitro.
TRF1 and TRF2 use different mechanisms to find telomeric DNA but share a novel mechanism to search for protein partners at telomeres.
TRF1 ensures the centromeric function of Aurora-B and proper chromosome segregation.
TRF1 negotiates TTAGGG repeat-associated replication problems by recruiting the BLM helicase and the TPP1/POT1 repressor of ATR signaling.
TRF2 and lamin A/C interact to facilitate the functional organization of chromosome ends.
TRF2 recruits RTEL1 to telomeres in S phase to promote t-loop unwinding.
TRF2-Mediated Control of Telomere DNA Topology as a Mechanism for Chromosome-End Protection.
TRF2-mediated stabilization of hREST4 is critical for the differentiation and maintenance of neural progenitors.
TRF2-tethered TIN2 can mediate telomere protection by TPP1/POT1.
Triage biodosimetry using centromeric/telomeric PNA probes and Giemsa staining to score dicentrics or excess fragments in non-stimulated lymphocyte prematurely condensed chromosomes.
Triallelic and epigenetic-like inheritance in human disorders of telomerase.
Triplex intermediates in folding of human telomeric quadruplexes probed by microsecond-scale molecular dynamics simulations.
Trypanosoma brucei TIF2 suppresses VSG switching by maintaining subtelomere integrity.
Tryptophan-Dependent Control of Colony Formation After DNA Damage via Sea3-Regulated TORC1 Signaling in Saccharomyces cerevisiae.
Tumor viruses and replicative immortality--avoiding the telomere hurdle.
Tumor-Induced Senescent T Cells with Suppressor Function: A Potential Form of Tumor Immune Evasion
Tumour suppressors and cellular senescence.
Turning telomerase into a Jekyll and Hyde case?
Two distinct promoter architectures centered on dynamic nucleosomes control ribosomal protein gene transcription.
Two routes to senescence revealed by real-time analysis of telomerase-negative single lineages.
Two-step mechanism involving active-site conformational changes regulates human telomerase DNA binding.
U-shaped association between telomere length and esophageal squamous cell carcinoma risk: a case-control study in Chinese population.
Ultra-sensitive detection of Plasmodium falciparum by amplification of multi-copy subtelomeric targets.
Uncategorized
Understanding Idiopathic Interstitial Pneumonia: A Gene-Based Review of Stressed Lungs.
Unicellular eukaryotes as models in cell and molecular biology: critical appraisal of their past and future value.
Unique aspect of Tibetan medicine.
Unique C. elegans telomeric overhang structures reveal the evolutionarily conserved properties of telomeric DNA.
Unraveling the pathogenesis of Hoyeraal-Hreidarsson syndrome, a complex telomere biology disorder.
Up-regulating telomerase and tumor suppressors: focusing on anti-aging interventions at the population level.
Update in genetic susceptibility in melanoma.
Uremia-associated immunological aging is stably imprinted in the T-cell system and not reversed by kidney transplantation.
Uremia-Associated Premature Ageing Of T Cells Does Not Predict Infectious Complications After Renal Transplantation.
Using amino-labeled nucleotide probes for simultaneous single molecule RNA-DNA FISH.
Using Centromere Mediated Genome Elimination to Elucidate the Functional Redundancy of Candidate Telomere Binding Proteins in Arabidopsis thaliana.
Utilizing murine inducible telomerase alleles in the studies of tissue degeneration/regeneration and cancer.
Variable telomere length across post-mortem human brain regions and specific reduction in the hippocampus of major depressive disorder.
Variants in TERT influencing telomere length are associated with paranoid schizophrenia risk.
Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk.
Variation in early-life telomere dynamics in a long-lived bird: links to environmental conditions and survival.
Variation of DNA methylation in candidate age-related targets on the mitochondrial-telomere axis in cord blood and placenta.
Variations in exon-2 of SBDS gene and its association with aplastic anemia.
Variations in telomere maintenance and the role of telomerase inhibition in gastrointestinal cancer.
Various Mechanistic Pathways Representing the Aging Process Are Altered in COPD.
Vascular Smooth Muscle Cell Senescence Promotes Atherosclerosis and Features of Plaque Vulnerability.
VIH2 Regulates the Synthesis of Inositol Pyrophosphate InsP8 and Jasmonate-Dependent Defenses in Arabidopsis.
Visfatin/Nampt induces telomere damage and senescence in human endothelial cells.
vision
Visual detection of telomerase activity with a tunable dynamic range by using a gold nanoparticle probe-based hybridization protection strategy.
Visualization and quantitative analysis of extrachromosomal telomere-repeat DNA in individual human cells by Halo-FISH.
Visualization of Telomere Integrity and Function In Vitro and In Vivo Using Immunofluorescence Techniques.
Voltammetric characterization of human telomeric G-quadruplex: A label free method for anticancer drug detection.
Water-soluble isoindolo[2,1-a]quinoxalin-6-imines: in vitro antiproliferative activity and molecular mechanism(s) of action.
Weight loss associated with bariatric surgery does not restore short telomere length of severe obese patients after 1 year.
Werner Syndrome-specific induced pluripotent stem cells: recovery of telomere function by reprogramming.
What determines ageing of the transplanted liver?
Where You Live May Make You Old: The Association between Perceived Poor Neighborhood Quality and Leukocyte Telomere Length.
Whole exome sequencing in an Indian family links Coats plus syndrome and dextrocardia with a homozygous novel CTC1 and a rare HES7 variation.
Whole Genome Sequencing Reveals a Chromosome 9p Deletion Causing DOCK8 Deficiency in an Adult Diagnosed with Hyper IgE Syndrome Who Developed Progressive Multifocal Leukoencephalopathy.
Whole-Body Induced Cell Turnover: A Proposed Intervention for Age-Related Damage and Associated Pathology.
Whole-exome sequencing identifies somatic ATRX mutations in pheochromocytomas and paragangliomas.
Widespread telomere instability in prostatic lesions.
Wild sex in zebrafish: loss of the natural sex determinant in domesticated strains.
Will knowing my telomere length really improve my life?
Within the genome, long telomeres are more informative than short telomeres with respect to fitness components in a long-lived seabird.
Without children is required for Stat-mediated zfh1 transcription and for germline stem cell differentiation.
Work-Related Exhaustion and Telomere Length: A Population-Based Study
WRN loss induces switching of telomerase-independent mechanisms of telomere elongation.
WRN translocation from nucleolus to nucleoplasm is regulated by SIRT1 and required for DNA repair and the development of chemoresistance.
X-linked dyskeratosis congenita presenting in adulthood with photodamaged skin and epiphora.
XAV939 promotes apoptosis in a neuroblastoma cell line via telomere shortening.
XRCC3 is a promising target to improve the radiotherapy effect of esophageal squamous cell carcinoma.
Zinc finger protein 637 protects cells against oxidative stress-induced premature senescence by mTERT-mediated telomerase activity and telomere maintenance.
ZSCAN4 and TRF1: A functionally indirect interaction in cancer cells independent of telomerase activity.
Zscan4 interacts directly with human Rap1 in cancer cells regardless of telomerase status.
β-cell telomere attrition in diabetes: inverse correlation between HbA1c and telomere length.
γH2AX foci on apparently intact mitotic chromosomes: not signatures of misrejoining events but signals of unresolved DNA damage.
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