Telomere Science Library

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about the Nobel-Prize Winning Science of Telomere Biology

Telomerase Activating Supplements

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Owing to a dramatic increase in average life expectancy and the Family Planning program of the 1970s - 1990s, China is rapidly becoming an aging society. Therefore, the investigation of healthspan-extending drugs becomes more urgent. Astragalus membranaceus (Huangqi) is a major medicinal herb that has been commonly used in many herbal formulations in the practice of traditional Chinese medicine (TCM) to treat a wide variety of diseases and body disorders, or...
Published 12/01/2017    Read More...
Salvador L, Singaravelu G, Harley CB, Flom P, Suram A, Raffaele JM. TA-65 is a dietary supplement based on an improved formulation of a small molecule telomerase activator that was discovered in a systematic screening of natural product extracts from traditional Chinese medicines. This study summarizes the findings on telomere length...
Published 03/30/2016    Read More...
Telomere attrition and corresponding cellular senescence of the retinal pigment epithelium contribute to the changes of age-related macular degeneration. Activation of the enzyme telomerase can add telomeric DNA to retinal pigment epithelium chromosomal ends and has been proposed as a treatment for age-related macular degeneration. We report the use of a small molecule, oral telomerase activator (TA)-65 in early macular degeneration. This study, focusing on early macular degeneration, provides a...
Published 01/28/2016    Read More...
By T.A. Sciences ®Harley CB, Liu W, Blasco MA, Vera E, Andrews WH, Briggs LA, Raffaele JM. Rejuvenation Research. February 14, 2011 (1): 45-56. This one year human study showed improvements in telomere length and immune system biomarkers for people taking TA-65® capsules. The study confirmed TA-65®'s previously noted health effects...
Published 02/14/2011    Read More...
By T.A. Sciences ® | 14th November 2013 An observational study published in the October 2013 issue of Rejuvenation Research reports on observed changes in metabolic and cardiovascular health markers in people who took TA-65MD® nutritional supplements for one year. Read More...
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By T.A. Sciences ® Molgora B, Bateman R., Sweeney G., Finger D., Dimler T., Effros R.B., Valenzuela H.F., Cells Journal. 2013 January 14: ISSN 2073-4409 This human study demonstrates that TA-65MD® nutritional supplements increase telomerase activity and proliferation in human CD4 and CD8 T cells. It highlights the importance of Telomerase...
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By T.A. Sciences ® de Jesus BB, Schneeberger K, Vera E, Tegera A, Harley CB, Blasco MA. Aging Cell. 2011 August; 10(4): 604-621. This animal study looked at the effects of TA-65® and confirmed their mechanism of action, long-term effects, and safety. Study Model: To confirm mechanism of action (through Telomerase Activation),...
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By T.A. Sciences ® In the largest and most diverse study of aging to date, telomere length is being analyzed as a marker for age-related conditions. This genomic project, Genetic Epidemiology Research on Adult Health and Aging (GERA), aims to increase understanding of the genetic basis for a host of...
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By T.A. Sciences ® Jaskelioff M., Muller F.L., Paik J.H., Thomas E., Jiang S., Adams A.C., Sahin E., Kost-Alimova M., Protopopov A., Cadiñanos J., Horner J.W., Maratos-Flier E., Depinho R.A. Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice. Nature. 2011;469(7328):102-106. According to a study published in the January 2011 issue of...
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