Telomere Science Library

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Neuroprotection and safety profile of Astragalus membranaceus extract TA-65 in neonatal hypoxic-ischemic brain damage by activating mitochondrial telomerase reverse transcriptase: Evidence from in vitro and in vivo studies

Authors: Jiao Li, Zhi Fang, Jing Shi, Yi Feng, Haiting Liu, Hongju Chen Publication: Journal of Ethnopharmacology, Volume 351, 24 July 2025, 120073 Abstract Ethnopharmacological relevance: Astragalus membranaceus is one of the most widely applied traditional Chinese herbal medicines. TA-65 is an extract of Astragalus membranaceus; however, the protective effects...
Published 06/11/2025    Read More...

Shorter Telomere Length Linked to Increased Risk of Stroke, Dementia, Depression

A recent study published in Stroke found that shorter leukocyte telomere length (LTL) is linked to an increased risk of stroke, dementia, and late-life depression. Researchers analyzed data from over 356,000 UK Biobank participants and observed that individuals with the shortest LTL had an 8% higher risk of stroke, a...
Published 02/18/2025    Read More...

Beneficial Effects of Telomerase Activator (TA-65) Against Neurobiology

Authors: Yuan Yao, Maria Luz Fernandez Published: 01/27/2017, EC Nutrition Abstract The telomere activator-65 (TA-65), extracted from the Chinese herb Radis astragali, has been shown to have protective effects against a number of chronic conditions including insulin resistance, neural depression, cardiovascular disease and age-related macular degeneration among others. Telomeres are protective nucleotide repeats...
Published     Read More...