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Are short telomeres hallmarks of cancer recurrence?

Authors: Jerry W JW. Shay
Published: 12/23/2013, Clinical cancer research : an official journal of the American Association for Cancer Research


Exposure to radiation and some chemotherapeutic agents is associated with an increased risk of developing second cancers. Short telomeres are almost universally associated with malignant cancer progression. An unanswered question is whether inherited short telomeres or therapy-related telomere shortening is a biomarker of the development of second malignant neoplasms.

©2013 AACR
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